| Alternative splicing determines the intracellular localization of the novel nuclear protein Nop 30 and its interaction with the splicing factor SRp30c . ^^^ Interaction studies in yeast , in vitro protein interaction assays , and co immunoprecipitations demonstrated that Nop 30 multimerizes and binds to the RS domain of SRp30c but not to other splicing factors tested . ^^^ |