| Interacting proteins: Q16653 and Q13224 |
Pubmed |
SVM Score :0.0 |
| The authors show that glutamate applied to the synaptic region of the MoG mimics the depolarisation of the chemical input and can also block spike transmission from the GFs . ^^^ Glutamate has no effect on the presynaptic GF , and the effects in the MoG are maintained in the presence of cadmium , indicating that the glutamate is acting directly on the MoG . ^^^ Immunocytochemical staining shows that , whereas some synaptic profiles impinging on the MoG contain pleomorphic agranular vesicles and are immunoreactive to GABA and not glutamate ( as previously reported ) , there are at least as many other profiles that contain round , agranular vesicles and that are immunoreactive to glutamate and not to GABA . ^^^ |
|
| Interacting proteins: Q16653 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Therefore , we examined whether riluzole , an inhibitor of glutamate transmission , affects the pathogenesis and clinical features of MS like disease in myelin oligodendrocyte glycoprotein ( MOG ) induced EAE in mice . ^^^ |
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