| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Postsynaptic localization of N methyl D aspartate type glutamate receptors may be mediated by the synapse associated proteins ( SAPs ) SAP 90 , SAP 102 , and chapsyn 110 . ^^^ |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| PSD 95 ( SAP 90 ) , SAP 102 and Chapsyn 110 ( PSD 93 ) are members of the membrane associated guanylate kinase family , and interact with N methyl D aspartate ( NMDA ) receptor NR2A ( GluRepsilon 1 ) and NR2B ( GluRepsilon 2 ) subunits and with Shaker type K+ channel subunits to cluster into a channel complex . ^^^ |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| From Western blots of hippocampus and immunogold analysis of CA 1 synapses , the high expression of NR2B at P 2 coincides with the high level of SAP 102 at synapses , whereas the later expression of NR2A coincides with that of PSD 93 and PSD 95 . ^^^ To determine whether the changes in PSD 93 / 95 and SAP 102 reflect preferred associations with NR2A and NR2B , respectively , we measured co immunoprecipitation in the adult hippocampus . ^^^ These studies suggest that there is a preference for complexes of NR2A / PSD 93 / 95 and NR2B / SAP 102 . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| By using a sensitive immunogold procedure , we have investigated the organization of two synaptic scaffolding molecules , PSD 95 and PSD 93 , as well as N methyl D aspartate ( NMDA ) and alpha amino 3 hydroxy 5 methylisoxazole 4 proprionic acid ( AMPA ) receptors , at these heterogeneous glutamate signaling sites . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| We report here that postsynaptic density 93 protein ( PSD 93 ) , a postsynaptic neuronal MAGUK , is expressed abundantly in spinal dorsal horn and forebrain , where it colocalizes and interacts with NMDAR subunits NR2A and NR2B . ^^^ Targeted disruption of the PSD 93 gene reduces not only surface NR2A and NR2B expression but also NMDAR mediated excitatory postsynaptic currents and potentials , without affecting surface AMPA receptor expression or its synaptic function , in the regions mentioned above . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Internalization assays reveal that like PSD 95 , both SAP 97 and PSD 93 inhibit NR2B mediated endocytosis . ^^^ |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| In the absence of PSD 93 , PSD 95 still interacted with NR2B and nNOS . ^^^ |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Each family of PSD proteins is selective for a given glutamate receptor subtype , the most well characterized being the NMDA receptor binding proteins PSD 93 , PSD 95 , NF L , and SAP 102 . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated dopamine glutamate interactions by measuring the expression of transcripts encoding the subunits for the ionotropic glutamate receptors ( NMDA , AMPA and kainate ) and five NMDAR associated intracellular proteins , PSD 93 , PSD 95 , SAP 102 , NF L and yotiao in the dopaminergic neurons in the substantia nigra pars compacta ( SNc ) of subjects with schizophrenia and a comparison group . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Here we report a direct interaction between the strong inward rectifier , Kir2 . 1 , and a recently identified splice variant of postsynaptic density 93 ( PSD 93 ) , a protein involved the subcellular targeting of ion channels and glutamate receptors at excitatory synapses . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| Using immunoautoradiography the expression levels of NR 1 and NR2B subunits of the NMDA receptor and the postsynaptic density scaffold proteins , PSD 95 , PSD 93 , and neurofilament light ( NFL ) were examined in normal common marmosets ( Callithrix jacchus ) and 1 methyl 4 phenyl 1 , 2 , 3 , 6 tetrahydropyridine ( MPTP ) lesioned animals that exhibited high or low levels of l DOPA induced dyskinesia . ^^^ |
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| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15700 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|