| Interacting proteins: P63244 and Q13224 |
Pubmed |
SVM Score :0.9217709 |
| Peptides that disrupt the interactions between RACK 1 , NR2B , and Fyn induce phosphorylation and potentiate NMDA receptor mediated currents . 0.9217709^^^ We found that RACK 1 binds both the NR2B subunit of the NMDA receptor and the nonreceptor protein tyrosine kinase , Fyn . 0.58203961^^^ |
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| Interacting proteins: P63244 and Q13224 |
Pubmed |
SVM Score :0.58203961 |
| We found that RACK 1 binds both the NR2B subunit of the NMDA receptor and the nonreceptor protein tyrosine kinase , Fyn . 0.58203961^^^ |
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| Interacting proteins: P63244 and Q13224 |
Pubmed |
SVM Score :0.0 |
| On the basis of these findings plus the somatodendritic localization of RACK 1 , we hypothesize that metabotropic glutamate receptor triggered binding of activated PKCbeta 2 to mRNP complexes bound to polyA mRNAs is involved in activity triggered control of protein synthesis . . ^^^ |
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| Interacting proteins: P63244 and Q13224 |
Pubmed |
SVM Score :0.0 |
| We demonstrate that , in the hippocampus but not in the cerebral cortex , Fyn is targeted to the NR2B subunit of the NMDA receptor by the scaffolding protein RACK 1 . ^^^ During acute exposure to ethanol , RACK 1 is dissociated from the complex , thereby facilitating Fyn mediated phosphorylation of NR2B , which enhances channel activity , counteracting the inhibitory actions of ethanol . ^^^ |
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| Interacting proteins: P63244 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
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