Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
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Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We conclude that lactate alone and combined with other substrates decreases ammoniagenesis primarily at the glutamate dehydrogenase step and that slices from acidotic rats are relatively resistant to substrate mediated inhibition . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The degradation of exogenous glutamine to glutamate is apparently a necessary step in the accumulation of glutamine and arginine within the conidia . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The patients presumably have a deficiency in activity of the hepatic enzyme , glutamate formiminotransferase , which carries out the fourth sequential step in the main pathway of histidine degradation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The activity of L pyrrolidone carboxylate hydrolase was many times lower than the activities of the other enzymes , and thus the conversion of L pyrrolidone carboxylate to L glutamate is likely to be the rate limiting step of the cycle . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
If the decarboxylation of glutamate occurs with retention of configuration , the irreversible inhibition of this enzyme by the 4 ( R ) isomer can be rationalized on the basis of reversibility of the protonation step in the normal catalytic mechanism . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Thus , glutamine synthetase appears to catalyze the initial step in the assimilation of N 2 derived or exogenous NH4+ by these organisms . [ 13N ] Glutamate is , in all cases , the second major product of assimilation of 13N labeled N 2 and NH4+ . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The second step is the oxidation of delta 1 pyrroline 5 carboxylate to glutamate and delta 1 pyrroline 3 hydroxy 5 carboxylate to gamma hydroxy glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The differences are not due to enzyme inhibitors or activators , and kinetic analysis reveals the change to be one of greater tissue content of the same enzyme . delta 1 Pyrroline 5 carboxylate dehydrogenase , which converts PC to glutamate , shows a two to three fold increase in both tissues , paralleling the changes in PO with development . delta 1 Pyrroline 5 carboxylate reductase ( PCR ) , the enzyme which catalyzes the committed step in endogenous proline formation , undergoes oppositely directed changes , such that adult levels are only 20 % 25 % of fetal levels in liver and kidney . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Thus glutamate dehydrogenase per se , and not glutamate penetration , constitutes the control step for gluttochondria of glutamate with externally added oxaloacetate ( arsenite present ) that exclude an obligatory transport of oxaloacetate on the alpha oxoglutarate carrier . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The conversion of glutamate to 5 oxoproline was markedly inhibited by reduced glutathione , which exerted its effect on the gamma glutamyl cysteine synthetase step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
A slow obligatory proton release step precedes hydride transfer in the liver glutamate dehydrogenase catalytic mechanism . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It is concluded that transamination of glutamate rather than oxidative deamination catalyzed by glutamate dehydrogenase is the first step in the entry of glutamate carbon into the citric acid cycle in cultured astrocytes . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The PRO 1 gene of Saccharomyces cerevisiae encodes the 428 amino acid protein gamma glutamyl kinase ( ATP : L glutamate 5 phosphotransferase , EC 2 . 7 . 2 . 11 ) , which catalyzes the first step in proline biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
A protein band recognized by antibodies against specific amino acid sequences of the glutamate receptor A subunit was enriched with each purification step ; the molecular mass of this band ( 105 kDa ) corresponded to that of cloned AMPA receptor subunits . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In order to investigate the role of this second aspartate rich domain in rat FPP synthase , we mutated the first or third aspartate to glutamate , expressed the wild type and mutant enzymes in Escherichia coli , and purified them to apparent homogeneity using a single chromatographic step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Benzene ring substituted analogues were synthesized from a protected pyrimidinyl propionaldehyde and a substituted benzoyl glutamate moiety by a key reductive amination step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Although it is recognized that 4 , 5 diaminovaleric acid , formed from glutamate 1 semialdehyde , functions as the intermediate in the last step of delta aminolevulinic acid formation from glutamate , the enantioselectivity of the participating glutamate 1 semialdehyde aminotransferase for 4 , 5 diaminovaleric acid has remained unknown . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In this article , we demonstrate that an increase in intracellular Ca2+ concentration may represent a specific common step ( s ) in the mechanism ( s ) of action of glutamate ( Glu ) and depolarizing agents on formation of inositol phosphates ( IPs ) in 8 day old rat forebrain synaptoneurosomes . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Thus , the inhibition of glutamate oxidation in astrocytes by ammonia and the compounded inhibitory effect of HE , ammonia and AOA appeared to be located beyond the glutamate dehydrogenation step within the tricarboxylic acid cycle . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We isolated and analysed a full length mouse brain glutamate dehydrogenase ( GLUD ) cDNA as a preliminary step to use the mouse model for the investigation of GLUD function in neurotransmission and neurodegeneration . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The enzyme could be involved in the first step of nitrogen metabolism , catalyzing the conversion of 2 oxoglutarate and ammonia to glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
If these thermodynamic parameters apply to the redox step of the enzyme catalyzed glutamate reaction , then the burst phase which results upon mixing the enzyme , L glutamate and NADP+ in stoichiometric amounts must contain a hidden nonredox step of large delta H 0 value to account for the curved Arrhenius plot observed for this phase ( A . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In cyanobacteria , green and purple sulphur bacteria , as in chloroplasts of higher plants and algae a three step pathway converts glutamate into 5 aminolevulinate . ^^^ The last step is the conversion of glutamate 1 semialdehyde into 5 aminolevulinate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
However , the reverse half reaction , initiated by addition of aspartate or glutamate to the pyridoxal form of the mutant enzyme , is only three orders of magnitude slower than that of the wild type enzyme , kmax of the observable rate limiting elementary step , i . e . the conversion of the external aldimine to the pyridoxamine form , being 7 . 0 10 10 ( 2 ) s 1 . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Activation of the N methyl D aspartate ( NMDA ) subclass of glutamate receptors is a critical step in the selection of appropriate synaptic connections in the developing visual systems of cat and frog . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Calcium ion influx through dihydropyridine sensitive , voltage dependent calcium channels may be an important step in the neuronal injury induced by the prolonged activation of NMDA or non NMDA glutamate receptors . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
ALA auxotrophic hemL mutant S . typhimurium cells are deficient in glutamate 1 semialdehyde ( GSA ) aminotransferase , the enzyme that catalyzes the last step of ALA synthesis via the five carbon pathway . hemL cells transformed with a plasmid containing the S . typhimurium hemL gene did not require ALA for growth and had GSA aminotransferase activity . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In many organisms aminolevulinate is synthesized from glutamate in a three step pathway ( C 5 pathway ) . ^^^ The key step in this conversion is a tRNA mediated reduction of glutamate to glutamate 1 semialdehyde . tRNA is a specific cofactor for an NADPH dependent enzyme , Glu tRNA reductase , which is capable of sequence specific recognition of Glu tRNA ( Glu ) . tRNA ( Glu ) is a dual function molecule ; it participates both in protein and in aminolevulinate biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The reconstitution experiments described here provide a functional assay for the solubilized vesicular glutamate uptake system and represent an initial step towards the purification of the glutamate translocator . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The evidence indicated that the rate limiting step in respiratory states 2 and 4 would be osmotically insensitive , as opposed to the osmotically sensitive respiration of states 1 and 3 and uncoupler stimulated respiration with glutamate + malate and succinate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Activation of glutamate by gamma glutamate kinase : formation of gamma cis cycloglutamyl phosphate , an analog of gamma glutamyl phosphate . gamma Glutamate kinase , the enzyme that catalyzes the first step in the pathway from glutamate to proline , has been postulated to convert glutamate to a gamma activated form ( possibly gamma glutamyl phosphate ) , which is reduced by a NADPH linked reductase to yield glutamate gamma semialdehyde ( in equilibrium with delta 1 pyrroline 5 carboxylate ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Pulse chase studies with carbon 14 labeled glutamine demonstrated a marked delay in glutamine conversion to glutamate , indicating that glutamine deamidation is a critical rate limiting step , and also provided evidence for metabolism of the glutamine carbon skeleton by the tricarboxylic acid cycle . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
One step and two step fluorometric assay methods for general aminotransferases using glutamate dehydrogenase . ^^^ One step and two step assay methods were developed for general aminotransferases ( ATs ) utilizing Glu and alpha ketoglutarate ( alpha KG ) as the donor and acceptor of the amino group , by coupling a glutamate dehydrogenase ( GDH ) reaction with the AT reactions . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The +0 . 60 pH shift upon the second papain cleavage is consistent with the loss of two negative charges and is supported by prior evidence that at least one of the three glutamate residues lost during the second proteolysis step is protonated and neutral in the intact protein . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Comparisons of ionic requirements , ligand specificity , and inhibitor sensitivities , however , suggest the described binding is the first step in a Cl dependent high affinity glutamate uptake system . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It is proposed that potassium antiport , while decreasing charge stoichiometry of Na+ / glutamate transport , increases the relative rate limitancy of the transport step translocating three cations ( probably two Na+ , one H+ ) together with one glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Here we demonstrate that in cell extracts of the unicellular cyanobacterium Synechocystis sp . strain PCC 6803 ALA was formed from glutamate in a series of reactions in which activation of glutamate by glutamyl tRNAGlu formation was the first step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The first order rate law that the glutamate dependent signal obeys suggests that the rate limiting step in the development of this signal is the dissociation of the dye from the mitochondrial membrane or the permeation of this membrane by the probe . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Three primary metabolic pathways of aspartate nitrogen disposition were identified : transamination with 2 oxoglutarate to form [ 15N ] glutamate , the nitrogen of which subsequently was transferred to glutamine , alanine , serine and ornithine ; condensation with IMP in the first step of the purine nucleotide cycle , the aspartate nitrogen appearing as [ 6 amino 15N ] adenine nucleotides ; condensation with citrulline to form argininosuccinate , which is cleaved to yield [ 15N ] arginine . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These studies show the power of multiple isotope effects in deducing details of the chemistry and changes in rate limiting step ( s ) in complicated reaction mechanisms such as those of alanine and glutamate dehydrogenases . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
With the use of glutamate dehydrogenase ( EC 1 . 4 . 1 . 2 ) in a second step , the assay measured the release of free glutamate from L alpha glutamyl L tryptophan by the increase in NADH fluorescence . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The RNA required in the first step of chlorophyll biosynthesis is a chloroplast glutamate tRNA . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These results may contribute to explain the higher incorporation in regenerating liver of 3H folic acid into folylpolyglutamates at a higher number of glutamate residues and is consistent with the hypothesis that the addition of glutamate represents a control step in folate coenzyme synthesis and consequently of one carbon metabolism . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a step in the evaluation of the role of growth hormone ( GH ) in mammary tumorigenesis , the effects of neonatal treatment with monosodium glutamate ( MSG ) on normal and neoplastic mammary growth , plasma levels of GH and prolactin ( PRL ) and the pattern of estrous cycles were determined in SHN virgin mice . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These phase alterations in the activity of the AC structures in basal ganglia were accompanied by the similar alterations in content of glutamate : an increase of glutamate at the 1 step of alcoholism and a decrease at the 3 step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The disparity between NH 3 production and PDG activity can not be explained by the difference in matrix glutamate level , thus raising the possibility that mitochondrial glutamine entry may be a rate limiting step for ammoniagenesis during K+ depletion . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Cell free preparations from the unicellular green alga , Chlorella vulgaris , catalyze the conversion of glutamate to delta aminolevulinate , which is the first committed step in heme and chlorophyll biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The glutamate dehydrogenase catalyzed reduction of delta 1 pyrroline 2 carboxylic acid ( PCA ; an alpha imino acid ) with reduced nicotinamide adenine dinucleotide phosphate ( NADPH ) to give L proline and NADP+ is employed as a model for the redox step of the corresponding enzyme catalyzed reductive amination of alpha ketoglutarate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Rates of transamination of glutamate and 4 aminobutyrate were similar , suggesting that the decarboxylation step is not entirely rate limiting in the normal mechanism . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Transient state intermediates involved in the hydride transfer step of the glutamate dehydrogenase reaction . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate cycle , first step of nitrogen metabolism in Bacillus megaterium ] . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Speed determining step in the reaction of glutamate dehydrogenase from bovine liver with monoaminodicarbonic acid and aminomonocarbonic acid as substrates ] . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Although blockage of the Krebs cycle at the alpha ketoglutarate dehydrogenase step is the basis for the accumulation of glutamate , significant Krebs cycle activity was found in glucose grown cells , and extensive Krebs cycle activity in cells metabolizing [ 1 13C ] acetate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Elaboration of the required oligo ( gamma L glutamate ) chain was achieved one unit at a time , beginning with the coupling of L glutamic acid dibenzyl ester with [ ( tert butyloxy ) carbonyl ] L glutamic acid alpha benzyl ester ( 7 ) , followed by selective removal of the tert butyloxycarbonyl grouping and another coupling step with 5 or 7 as required . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Elaboration of the required oligo gamma L glutamate chain was achieved one unit at a time beginning with the coupling of L glutamic acid dibenzyl ester with t butyloxycarbonyl L glutamic acid alpha benzyl ester ( 7 ) followed by selective removal of the t butyloxycarbonyl grouping and another coupling step with 5 or 7 as required . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate dehydrogenase ( L glutamate : NAD+ oxidoreductase ( deaminating ) ; EC 1 . 4 . 1 . 2 ) has been purified from Peptostreptococcus asaccharolyticus in a single step using dye ligand chromatography . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Legionella pneumophila was unable to grow in a chemically defined medium without arginine because it could not carry out the first step in the biosynthetic pathway , the conversion of glutamate to N acetylglutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This transfer of glutamate from an activated complex to tRNAGlu indicates that the formation of glutamyl tRNA is catalyzed via a two step reaction mechanism . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Malate , the product formed , is measured in a third enzymatic step with malate dehydrogenase in a medium of glutamate oxaloacetic transaminase . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
With norvaline , hydride transfer is a major rate limiting step , while with glutamate a step preceding hydride transfer is slower than hydride transfer . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Addition of NH4Cl plus glutamate caused an increase in both glutamate removal and glutamine synthesis , demonstrating that the supply of ammonia via glutamate dehydrogenase is the rate limiting step in glutamine formation from glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Currents were measured after a step application of glutamate or AMPA to patches excised from pyramidal cells of hippocampal slice cultures . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In the present study , we demonstrate that ( 1 ) in addition to muscarinic receptors , histamine H 1 subtypes and glutamate metabotropic receptors contribute to the first IP 3 increase ( first 10 min of seizures ) and ( 2 ) the histamine H 1 subtype and glutamate metabotropic receptors are also involved in the second step of inositol phosphate response ( after 10 min of seizures ) . alpha 1 adrenoceptor and 5 HT 2 receptors , known to be coupled to phosphoinositide turnover , did not participate in soman induced IP 3 response . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
After the initial binding ( suggested to be important for the decay of synaptic glutamate ) , it undergoes a conformational change which represents , or is tightly associated with , the transport step . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
C . 1 . 4 . 1 . 3 ) was added to the incubation buffer to degrade residual endogenous L glutamate , which was not entirely removed from the section after the prewashing step and interfered with [ 3H ] CGP 39653 binding . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This could reflect cleavage of [ 2 13C ] citrate and formation of [ 3 13C ] oxaloacetate and acetyl Coa , i . e . , the first step in fatty acid synthesis . [ 3 13C ] Oxaloacetate would , after entry into a TCA cycle , give the observed labeling of glutamate and GABA . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Comparison of the sensitivity of glutamate release evoked by secretogogues that act at various steps in the neurotransmitter release process suggests that halothane does not affect Ca ( 2+ ) secretion coupling or vesicle exocytosis but inhibits glutamate release at a step proximal to Ca2+ influx , perhaps by blocking presynaptic Na+ channels . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The present experiments have taken these observations a step further and compare the effects of several glycine site ligands with different affinities and intrinsic activities ( determined from equilibrium concentration response curves ) on glutamate off rate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This can be interpreted as implying that glutamate 268 may function as a general base necessary for the initial activation of the essential cysteine residue ( 302 ) , rather than being involved in only the deacylation or hydride transfer step . ( ABSTRACT TRUNCATED AT 250 WORDS ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The following step of the glutamine metabolizing pathway , allowing the entrance of the amino acid skeleton carbons in the Krebs cycle , might be catalyzed by both glutamate dehydrogenase and aspartate transaminase , the first being entirely mitochondrial and the latter 65 % mitochondrial . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step to elucidate the possibility that pinealocyte microvesicles store messenger molecules , such as neuroactive amino acids , we have studied the distributional pattern of glutamate immunoreactivity in the pineal gland of the Mongolian gerbil ( Meriones unguiculatus ) at both light and electron microscopic levels . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The glutamate mutase dependent on adenosylcobalamin ( coenzyme B 12 ) catalyzes the carbon skeleton rearrangement of ( S ) glutamate to ( 2S , 3S ) 3 methylaspartate , the first step of the glutamate fermentation pathway of the anaerobic bacterium Clostridium cochlearium . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The fast application of a 1 mM step of L glutamate for 50 100 msec in the presence of TTX and dizolcipine ( MK 801 ) onto patches excised from these neurons produced large glutamate activated currents ( GACs ) that decayed with a single or double exponential time course despite the continued presence of agonist . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Intermolecular nitrogen transfer in the enzymic conversion of glutamate to delta aminolevulinic acid by extracts of Chlorella vulgaris . delta Aminolevulinic acid ( ALA ) , the universal biosynthetic precursor of tetrapyrrole pigments , is synthesized from glutamate in plants , algae , and many bacteria via a three step process that begins with activation by ligation of glutamate to tRNA ( Glu ) , followed by reduction to glutamate 1 semialdehyde ( GSA ) and conversion of GSA to ALA . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In the chloroplasts of plants , as in Escherichia coli , ALA is derived from the glutamate of Glu tRNA via the two step C 5 pathway . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
CGP 40116 provided widespread protection against seizure induced neuronal necrosis , suggesting that an essential step in its production is NMDA receptor activation by endogenous glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In previous transient state kinetic work from this laboratory , we proposed a new mechanism for the glutamate dehydrogenase catalyzed oxidative deamination reaction involving an initial replacement of a proton from lysine 126 by a single bound water molecule , followed by closure of the active site cleft and expulsion of bulk water , providing a hydrophobic environment for the ensuing hydride transfer step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This is the first step of the fermentation of glutamate by the strict anaerobic bacterium Clostridium cochlearium . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In a first step , the ability of propentofylline to inhibit in vitro the hippocampal evoked release of acetylcholine ( ACh ) and glutamate ( Glu ) , the two major neurotransmitters involved during soman intoxication , was demonstrated . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The key step in the regulation of urea production could be the stimulation of acetyl glutamate synthesis by amino acids entering the liver from the portal tract and the consequent activation of carbamoyl phosphate synthetase 1 . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We measured ammonium production rates , phosphate dependent glutaminase ( PDG ) activity , and glutamate dehydrogenase ( GDH ) activity in microdissected S 1 proximal tubules of rats to investigate the role of adaptations of PDG activity and GDH activity in response to a step increase in acid intake . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The predicted protein product has significant sequence similarity to Saccharomyces cerevisiae proline oxidase ( EC 1 . 5 . 99 . 8 ) , a mitochondrial enzyme which catalyzes the first step in the conversion of proline to glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These data indicate that new synthesis of the cytoskeleton associated Tau protein is a crucial step in the cascade of events promoted by glutamate and leading to neurodegeneration . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate 1 semialdehyde aminotransferase [ ( S ) 4 amino 5 oxopentanoate 4 , 5 aminomutase , EC 5 . 4 . 3 . 8 ] catalyzes the last step in the conversion of glutamate to delta aminolevulinate of which eight molecules are needed to synthesize a chlorophyll molecule . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Since glutamate receptors of the kainate subtype have been implicated in neurodegenerative disorders , establishing the precise map position of human GluR 7 subunit is an important step towards evaluating this locus as a candidate for mutations in neurodegenerative disorders . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Experimental probes selected to modify hepatic ureagenesis and carbamyl P production and utilization included : ( a ) NH4Cl , maintained at 5 mM by continuous infusion ( NH4+ is a substrate for carbamyl P synthase 1 and glutamate dehydrogenase ) ; ( b ) norvaline , an inhibitor of ornithine transcarbamylase which catalyzes the first committed step in the urea cycle ; and ( c ) ethoxyzolamide , an inhibitor of carbonic anhydrase which produces HCO 3 , an essential substrate for carbamyl P synthase 1 . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In vitro , the glutamate racemase activity shows an absolute requirement for UDP N acetylmuramoyl L alanine ( UDP MurNAc L Ala ) , the substrate of the D glutamic acid adding enzyme which catalyzes the subsequent step in the pathway for peptidoglycan synthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Reagent 1 , for the first step , contains a blanking system [ creatine amidinohydrolase ( CRTase ) , urease , glutamate dehydrogenase , NADPH , and 2 oxoglutarate ] and a NADPH regenerating system [ Mg ( 2+ ) dependent isocitrate dehydrogenase ( ICD ) , MgCl 2 , and excess isocitrate ] . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These experiments confirm that in the active enzyme Zn2+ plays a critical role in catalysis , that a histidine or glutamate residue plays a mechanistic role in the hydrolytic deamination step , and that cysteine is not involved in the catalytic mechanism of adenosine deaminase . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The postulated process involves anchoring of the 19 hydroxymethyl and 19 oxo groups at the active site by a glutamate residue , which also serves to activate the 19 oxo group for attack by ferric peroxy species in the third oxidative step . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The use of sodium glutamate to elute tubulin from the exchanger stabilizes the protein and facilitates the final polymerization step of the purification . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In the first step , glutamyl tRNA reductase ( GluTR ) , converts glutamate of glutamyl tRNA to glutamate 1 semialdehyde ( GSA ) which is rearranged to ALA by glutamate 1 semialdehyde 2 , 1 aminomutase ( GSA A ) in the second step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The step amplitudes had two discrete values of 9 . 4 and 18 . 5 pA at 60 mV , due to openings of junctional glutamate receptor channels . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These findings suggest that Ca2+ release from a TMB 8 sensitive intracellular store may be a necessary step in the onset of glutamate induced excitotoxicity in granule cells . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
During recovery from osmotic stress , accumulated proline is rapidly oxidized to glutamate and the first step of this process is catalyzed by proline oxidase . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This last purification step resulted in the separation of modulator 2 from glutamate , aspartate , and gamma aminobutyrate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The enzyme glutamyl tRNA ( Glu ) reductase catalyzes the second step in this pathway , the reduction of tRNA bound glutamate to give glutamate 1 semialdehyde . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Nuclear disintegration as a leading step of glutamate excitotoxicity in brain neurons . ^^^ These results indicate that glutamate excitotoxicity in the brain neuron does not fulfill morphological criteria of apoptosis , but suggest that the nuclear disintegration associated with DNA fragmentation is involved as a leading step in glutamate excitotoxicity . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
A sudden surge in the release of glutamate is currently believed to be an important initiating step in neuronal damage due to an ischemic insult . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Cells maintained by glycolytic ATP , i . e . , in the presence of the mitochondrial ATP synthase inhibitor oligomycin , remain viable for several hours but are still susceptible to glutamate ; thus , disruption of mitochondrial ATP synthesis is not a necessary step in glutamate excitotoxicity . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The first committed step of porphyrin synthesis in higher plants is the reduction of glutamyl tRNA to glutamate 1 semialdehyde . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Our findings suggest that cleavage of key cytoskeletal elements is an important step in glutamate induced neuronal apoptosis . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The abnormally low intrinsic KIE required to simulate both the alpha deuterio L glutamate reaction and its protio counterpart implies that the transition state of the hydride transfer step must be highly asymmetric . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Because both responses are the result of a decreased glutamate uptake , the present study was designed to determine whether the transport step or resulting fall in cellular glutamate modulates PP . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The neurotransmitter signal , experienced by multi state N methyl D aspartate ( NMDA ) and L alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionate ( AMPA ) type glutamate receptors at specific points in a synaptic cleft , is approximated by a series of step functions of different intensity and duration and used to drive a Markovian , multi state kinetic scheme that describes receptor gating . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
While most GABA is generated by glutamate decarboxylase ( GAD ) , an alternative synthetic pathway is known to originate from putrescine , which is converted via gamma aminobutyraldehyde in an aldehyde dehydrogenase requiring step to GABA . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step towards knowing the various functions of septal cholinergic neurons , we characterized the functional properties of glutamate , GABA ( type A ; GABAA ) and glycine receptor channels on cultured rat septal neurons which were histologically identified to be cholinergic . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The enhanced oxidation of [ 14C ] glutamate may be attributed to the function of alpha KIC as a nitrogen acceptor from [ 14C ] glutamate yielding [ 14C ] alpha ketoglutarate , an intermediate of the tricarboxylic acid cycle . [ 14C ] glutamine oxidation was not stimulated as much as [ 14C ] glutamate oxidation and only increased at 10 mM alpha KIC reflecting the extra metabolic step required for its oxidative metabolism . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It was concluded that at least a part of the effect of glutamate replacement is on RNA polymerase promoter interaction , and most likely the association step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We conclude that pyruvate carboxylase is required for de novo synthesis of glutamate plus glutamine , but that conversion of alpha ketoglutarate to glutamate may frequently be the rate limiting step in this process of glutamate synthesis . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Photolytic uncaging and release of free glutamate occur in two steps , consisting of an initial light induced cleavage that proceeds on the sub millisecond time scale , and a subsequent light independent , pH dependent decarboxylation step that proceeds on the millisecond time scale . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate dehydrogenase from Giardia intestinalis was purified 680 fold to electrophoretic homogeneity with a 42 % recovery through a two step procedure . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Five different systems for fast determination of aspartate and glutamate in microdialysis samples are described : ( 1 ) a high speed HPLC using a gradient pump with a sharp elution profile , ( 2 ) a column switching technique , ( 3 ) an isocratic pump with a low pressure switching valve for one step gradients , ( 4 ) microbore chromatography using injections of acetonitrile as a wash out step , ( 5 ) on line connection of microdialysis and HPLC / derivatization . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate receptor activation results in calcium influx which is a determinant step leading to cell death . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This represents a first step towards understanding the role of subunit composition in determining neurosteroid modulation of ionotropic glutamate receptor function . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The aim of this work was to assess whether nicotine prevents glutamate neurotoxicity in primary cultures of cerebellar neurons , to try to identify the receptor mediating the protective effect and to shed light on the step of the neurotoxic process which is prevented by nicotine . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The Thioctamide ( 25 mg / kg body weight ) produced more noxious effects than protective ones , which were detected by a high level of Glutamate piruvate transaminase activity and a decrease of the hepatic Uroporphyrinogen decarboxylase activity , at its first step of decarboxylation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The inhibitory amino acid neurotransmitter gamma aminobutyric acid ( GABA ) is synthesized from glutamate in a single step by the enzyme glutamatic acid decarboxylase ( GAD ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In many bacteria , including the enteric species Salmonella typhimurium and Escherichia coli , heme is synthesized starting from glutamate by a pathway in which the first committed step is catalyzed by the hemA gene product , glutamyl tRNA reductase ( HemA ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Delta 1 Pyrroline 5 carboxylate synthase ( P5CS ; EC not assigned ) , a mitochondrial inner membrane , ATP and NADPH dependent , bifunctional enzyme , catalyzes the reduction of glutamate to Delta 1 pyrroline 5 carboxylate , a critical step in the de novo biosynthesis of proline and ornithine . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The proposed rate limiting step of the reaction catalyzed by glyoxalase 1 is the proton abstraction from the C 1 carbon atom of the substrate by a glutamate residue , resulting in a high energy enolate intermediate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
CR 6 did not prevent glutamate induced activation of NO synthase , but interfered with the glutamate NO cGMP pathway at a later step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
This step may be related to the yeast specific spacing between TATA elements and start sites since mutations of the corresponding glutamate in mammalian TFIIB do not produce a similar effect . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The formation of substrate radicals when the enzyme was reacted with either glutamate or methylaspartate was examined by measuring the rate at which 5 ' deoxyadenosine was formed , and shown to be sufficiently fast for this step to be kinetically competent . ^^^ For the conversion of glutamate to methylaspartate , a single chemical step appeared to dominate the overall rate , whereas in the reverse direction a lag phase was observed , suggesting the accumulation of an intermediate , tentatively ascribed to glycyl radical and acrylate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Exposure of primary neuronal cultures to glutamate also led to a significant increase in the concentration of a low molecular weight form of STEP . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As mitochondrial depolarisation may represent a pivotal step in the progression to cell death , we have used digital imaging techniques to examine the relationship between cytosolic Ca2+ concentration ( [ Ca2+ ] c ) and mitochondrial potential ( DeltaPsim ) during glutamate toxicity , and to define the mechanisms underlying mitochondrial dysfunction . 2 . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The present results suggest that activation of calcium / calmodulin dependent protein kinases may represent an important step in the cascade of intracellular events that leads to phosphorylation of cyclic AMP response element binding protein and subsequent induction of c fos gene after activation of ionotropic glutamate receptors by baroceptive signals in the nucleus tractus solitarii . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
KGDHC catalyzes a critical step in the Krebs tricarboxylic acid cycle , which is also a step in the metabolism of the potentially excitotoxic neurotransmitter glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
At basic pH , the solvent isotope effect of 2 . 3 , characterized by a unique pK ( a ) of 7 . 7 , and the linearity of the proton inventory showed that the rate limiting process for deacylation is associated with the hydrolysis step and suggested that the glutamate form of Glu 268 acts as a base catalyst in this process . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Consequently , the results indicate that proton transfer from the glutamate controls the rate of all events during the F > O reaction step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The aim of this work was to assess whether MT 3 is able to prevent glutamate neurotoxicity and to identify the step of the neurotoxic process interfered with by MT 3 . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Our results indicate a rapid glutamate binding step occurring on a submillisecond time scale that precedes subsequent slower electrogenic glutamate translocation across the membrane within a few milliseconds . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The study was aimed at evaluating the extent of flux control exercised by the amino acid excretion step on the glutamate production flux in C . glutamicum 2262 strain that is induced for glutamate excretion by an upward temperature shift . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The sluggish A ( slgA ) gene of Drosophila melanogaster has been shown to encode for the enzyme proline oxidase , a mitochondrial enzyme which catalyzes the first step in the conversion of L proline to L glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The results can be quantitatively explained with an ordered binding model that includes a rapid proton binding step to the empty transporter followed by glutamate binding and translocation of the proton glutamate transporter complex . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Hyperammonemia with reduced ornithine , citrulline , arginine and proline : a new inborn error caused by a mutation in the gene encoding delta ( 1 ) pyrroline 5 carboxylate synthase . delta ( 1 ) pyrroline 5 carboxylate synthase ( P5CS ) , a bifunctional ATP and NADPH dependent mitochondrial enzyme , catalyzes the reduction of glutamate to delta ( 1 ) pyrroline 5 carboxylate , a critical step in the biosynthesis of proline , ornithine and arginine . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These results indicate that the substrate translocation step , which is not rate limiting for the overall turnover of the transporter with L glutamate , becomes rate limiting when D aspartate is translocated . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We have previously demonstrated that the glutamate induced increase in cytosolic Ca ( 2+ ) is likely responsible for blockade of the elongation step of protein synthesis , whereas Zn ( 2+ ) preferentially inhibits the initiation step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Physiological differentiation of the mitochondria during Bufo bufo development . 1 ) The oxygen consumption increases during Bufo bufo development in accordance with the two steps which border at the `` heart beat ' ' stage . 2 ) Cytochrome c oxidase activity is not proportional to the oxygen consumption : it is notable and constant in the first step , and it only increases in the second . 3 ) In the mitochondria of preneural embryos , citrate synthase , NADP+ dependent isocitrate dehydrogenase , and succinate dehydrogenase activities are very low in respect to malate dehydrogenase and glutamate oxaloacetate transaminase activities . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Rate limitation at the transaminase step is likely imposed by the limited supply of amino acids which provide the alpha amino group to glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Evidence exists that targeting of glutamate receptors to the different neuronal compartments is regulated at multiple levels involving a general targeting step ; a local step where receptor containing organelles are moved to the synapse ; and a step where the receptors are stabilized at the synapse , which may involve interaction with an anchoring protein . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate cysteine ligase ( GCL ; also referred to as gamma glutamylcysteine synthetase , GCS ) catalyzes the rate limiting step of glutathione synthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Rapid and sensitive step gradient assays of glutamate , glycine , taurine and gamma aminobutyric acid by high performance liquid chromatography fluorescence detection with o phthalaldehyde mercaptoethanol derivatization with an emphasis on microdialysis samples . ^^^ We developed a rapid step gradient HPLC method for determination of glutamate , glycine and taurine , and a separate method for determination of gamma aminobutyric acid ( GABA ) in striatal microdialysates . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The mitochondrial aspartate / glutamate carrier catalyzes an important step in both the urea cycle and the aspartate / malate NADH shuttle . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Peripherally membrane bound PutA catalyzes the two step oxidation of proline to glutamate , while cytoplasmic PutA represses the transcription of its own gene and the gene for a proline transporter protein . 10 ray crystallographic studies on PutA have been initiated to determine how the PutA structural scaffold enables it to be both an enzyme and a repressor , and to understand the mechanism by which PutA switches between its enzymatic and DNA binding functions . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Rigid rod beta barrels are composed of interdigitating , short , amphiphilic peptide strands that are flanked by stabilizing rigid rod `` staves . ' ' As a first step toward the construction of catalytic rigid rod beta barrels , we here report synthesis and study of a new barrel designed to comprise alternating leucine and histidine residues at the inner and lysine and glutamate residues at the outer barrel surface . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
EC ( 50 ) s for L glutamate and sodium are significantly lower after modification , consistent with kinetic models of the transport cycle that link anion channel gating to an early step in substrate translocation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The rate limiting step is the binding of glutamate and cysteine , which is catalyzed by the enzyme glutamate cysteine ligase ( GCL ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate accumulation into synaptic vesicles is a vital step in glutamate synaptic transmission . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We speculate that the purpose of this novel catalytic triad is to control the protonation of the acid / base glutamate , facilitating the first step of the catalytic reaction , protonation of the substrate , by the proton donor glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Lack of additivity for endobain E and glutamate paired stimulation on inositol phosphates accumulation suggested that they share at least a common step on inositol phosphate metabolism , as previously advanced for ouabain . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In the first step of tetrapyrrole biosynthesis in Escherichia coli , glutamyl tRNA reductase ( GluTR , encoded by hemA ) catalyzes the NADPH dependent reduction of glutamyl tRNA to glutamate 1 semialdehyde . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
We have previously demonstrated in cortical neurons that a glutamate induced increase in intracellular Ca ( 2+ ) is likely responsible for the blockade of the elongation step of protein synthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Vesicular glutamate transporter is a rate limiting step for glutamate release and is involved in the glutamate evoked exocytosis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Spontaneous activity was assessed at each step followed by iontophoretic glutamate ( GLU ) application to expose silent neurons . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The heterodimeric enzyme glutamate cysteine ligase catalyzes the first , rate limiting step in the de novo synthesis of glutathione . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Lithium induces brain derived neurotrophic factor and activates TrkB in rodent cortical neurons : an essential step for neuroprotection against glutamate excitotoxicity . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Investigation in vitro demonstrates that glial glutamate transport represents a critical step for triggering enhanced glucose utilization , but also lactate release from astrocytes through a mechanism involving changes in intracellular Na ( + ) concentration . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The key step in the fermentation of glutamate by Acidaminococcus fermentans is a reversible syn elimination of water from ( R ) 2 hydroxyglutaryl CoA to ( E ) glutaconyl CoA catalyzed by 2 hydroxyglutaryl CoA dehydratase , a two component enzyme system . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Excessive activation of glutamate receptors of the N methyl D aspartate ( NMDA ) subtype is considered a relevant initial step underlying different neurodegenerative diseases . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step towards this goal , the tritiated form of the high affinity group 2 metabotropic glutamate receptor ( mGluR ) antagonist LY 341495 [ K ( D ) ( mGluR ( 2 ) ) = 1 . 67 + / 0 . 20 nM , K ( D ) ( mGluR ( 3 ) ) = 0 . 75 + / 0 . 43 nM ] was evaluated to determine its potential to label mGluRs in vivo . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Gamma glutamylcysteine synthetase ( gamma GCS ) catalyzes the first and rate limiting step in glutathione ( GSH ) biosynthesis : the adenosine triphosphate ( ATP ) dependent ligation of glutamate and cysteine . gamma GCS consists of a catalytic ( gamma GCSH ) and modifier ( gamma GCSL ) subunit . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The nucleophilic alpha carboxylate moiety of glutamate is mispositioned with respect to both the ATP alpha phosphate and terminal tRNA ribose groups , suggesting that a component of amino acid discrimination resides at the catalytic step of the reaction . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These results indicate that KOP receptor activation inhibits GABA release by reducing Ca ( 2+ ) influx , but inhibits glutamate release at a step downstream of Ca ( 2+ ) entry . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
An effective cellular defense mechanism against oxidative stress is the tripeptide glutathione ( GSH ) , and the rate limiting step in GSH biosynthesis is catalyzed by the heterodimeric holoenzyme glutamate cysteine ligase ( GCL ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
One of the striking effects of HNE is that after a transient decrease in GSH , synthesis of GSH is elevated through induction of glutamate cysteine ligase ( GCL ) , which catalyzes the first step in de novo synthesis of GSH . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
To block the transport step electrochemically , extracellular Na+ concentration was lowered to one quarter , but this surprisingly left the inhibition of release by glutamate unaffected , showing inhibition to be associated to a step between binding and transport . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Thus the purpose of this study was to investigate the effects of the blockade of the AMPA and NMDA glutamate receptors , which have been suggested to mediate the transmission of information from the limbic system to this structure , on a classical aversive conditioning task the one trial step through inhibitory avoidance paradigm ( 24 h interval between training and testing ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The gltS argE operon of Lactococcus lactis encodes a putative glutamate or arginine transport protein and acetylornithine deacetylase , which catalyzes an important step in the arginine biosynthesis pathway . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate cysteine ligase ( GCL ) , composed of a catalytic ( GCLC ) and modulatory ( GCLM ) subunit , catalyzes the first step of glutathione ( GSH ) biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It differs , however , from GluRSs by the fact that the activation step is tRNA independent and that it does not catalyze attachment of the activated glutamate to E . coli tRNAGlu , but to another , as yet unknown tRNA . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Trimetazidine was able to inhibit the extracellular glutamate accumulation , which represents the first step of the excitotoxic phenomenon . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The findings suggest that glutamate may act via a reduction in the production of P 5 , which is the principal rate limiting step in the steroidogenic cascade , and not via modulation of steroidogenic enzyme activities . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Recent work shows that receptor exit from the endoplasmic reticulum represents a critical regulatory step in glutamate receptor trafficking to the neuronal cell surface . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Formylglycinamide ribonucleotide amidotransferase ( FGAR AT ) catalyzes the ATP and glutamine dependent formation of formylglycinamidine ribonucleotide , ADP , P ( 1 ) , and glutamate in the fourth step of de novo purine biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Formylglycinamide ribonucleotide amidotransferase ( FGAR AT ) catalyzes the ATP dependent conversion of formylglycinamide ribonucleotide ( FGAR ) and glutamine to formylglycinamidine ribonucleotide ( FGAM ) , ADP , P ( 1 ) , and glutamate in the fourth step of the purine biosynthetic pathway . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Formylglycinamide ribonucleotide amidotransferase ( FGAR AT ) catalyzes the conversion of formylglycinamide ribonucleotide ( FGAR ) , ATP , and glutamine to formylglycinamidine ribonucleotide ( FGAM ) , ADP , P ( 1 ) , and glutamate in the fourth step of the purine biosynthetic pathway . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Our results suggest that UPR signaling is a critical step in neural function that is needed for glutamate receptor assembly and secretion . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Although this suggests that , for the prokaryotic homolog , protonation of Glu ( 148 ) may be the first step in transporting Cl ( ) at the expense of H ( + ) transport in the opposite direction , an evolutionary argument might suggest that Cl ( ) opens the ClC gate in eukaryotic channels by inducing the conserved glutamate ' s protonation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Hypersensitivity of Fus ( r ) mutants to hydrogen peroxide is abolished by the presence of delta aminolevulinic acid , the precursor of heme synthesis , in the growth media and by the addition of glutamate or glutamine , amino acids required for the first step in heme biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Release of glutamine from astrocytes is an essential step of the glutamate glutamine cycle , and hence for the maintenance of neuronal glutamate and gamma aminobutyric acid ( GABA ) pools . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It can be derived from proline or glutamate , with the ultimate synthetic step catalyzed by argininosuccinate lyase . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate stimulation of current seems to be associated with a voltage dependent step , and the apparent valence of charge moved during binding is reduced in the R61A mutant . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
C . 5 . 1 . 1 . 3 ) catalyses the cofactor independent conversion of L glutamate to D glutamate , an essential step in the synthesis of components of the bacterial cell wall . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Delta 1 pyrroline 5 carboxylate synthase ( P5CS ) catalyses the reduction of glutamate to Delta 1 pyrroline 5 carboxylate , a critical step in the biosynthesis of proline , ornithine and arginine . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The conversion of citrate to isocitrate by c aconitase is the first step in a three step process leading to glutamate formation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Removal of glutamate from the synaptic cleft by astroglial glutamine synthase ( GS ) is a crucial step in the regulation of glutamate turnover and metabolism , thus participating in endogenous neuroprotective processes occurring within brain tissues . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These data suggest that the CML step may be necessary for magnesium and glutamate mediated activation of ACC . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In the first step of GSH synthesis , an amide linkage is formed between cysteine and glutamate catalyzed by gamma glutamylcysteine synthetase . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Kinetic measurement by LC / MS of gamma glutamylcysteine ligase activity . gamma Glutamylcysteine ligase ( GCL ) combines cysteine and glutamate through its gamma carboxyl moiety as the first step for glutathione ( GSH ) synthesis and is considered to be the rate limiting enzyme in this pathway . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The enzyme glutamyl tRNA reductase ( GTR ) , encoded by the hemA gene , catalyzes the first committed step in this pathway , which is the reduction of tRNA bound glutamate to produce glutamate 1 semialdehyde . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step in this process , we examined the effects of thimerosal on the transport of [ 3H ] d aspartate , a nonmetabolizable glutamate analog , in Chinese hamster ovary ( CHO ) cells transfected with two glutamate transporter subtypes , GLAST ( EAAT 1 ) and GLT 1 ( EAAT 2 ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
However , ammonia assimilation is a two step process and the second step , catalyzed by glutamate synthase , is exclusively located in plastids . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The enzyme glutamyl tRNA reductase ( GTR ) catalyzes the first committed step in this pathway , which is the reduction of tRNA bound glutamate to produce glutamate 1 semialdehyde . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In this study , the gene Delta 1 pyrroline 5 carboxylate dehydrogenase ( P5CDH ) , which catalyzes the second step in the conversion of proline to glutamate , is characterized in a number of cereal species . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The rate limiting step in synthesis of GSH is catalyzed by glutamate cysteine ligase ( GCL ) , a heterodimer composed of a catalytic subunit ( GCLC ) , and a modifier subunit ( GCLM ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
To address this issue , we used a vector based small hairpin RNA ( shRNA ) strategy to knock down each subunit of glutamate cysteine ligase ( GCL ; gamma glutamylcysteine synthetase ) , the heterodimeric enzyme that catalyzes the rate limiting step of glutathione biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step in this process , we examined the effects of Mn on the transport of [ D 2 , 3 3H ] D aspartate , a non metabolizable glutamate analog , in Chinese hamster ovary cells ( CHO ) transfected with two glutamate transporter subtypes , GLAST ( EAAT 1 ) or GLT 1 ( EAAT 2 ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
As a first step towards understanding mechanisms underlying plasticity at this synapse , we examined the effects of various drugs ( glutamate and GABA receptor agonists and antagonists , noradrenaline , and drugs affecting cAMP signaling ) on dendrodendritic mitral to granule cell synaptic transmission in an in vitro preparation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Glutamate 5 kinase ( G5K ) catalyzes the controlling first step of the synthesis of the osmoprotective amino acid proline , which feed back inhibits G5K . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The major PII interacting protein is the chloroplast localized enzyme N acetyl glutamate kinase , which catalyzes the key regulatory step in the pathway to arginine biosynthesis . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The advantages of this methodology include : ( 1 ) simple sample preparation ; ( 2 ) a single derivatization step ; ( 3 ) direct GC MS analysis of the reaction mix ; ( 4 ) high precision as a result of isotopic dilution analyses ; ( 5 ) high sensitivity and specificity as a result of strong [ MH ] ( + ) ions with ammonia reagent gas ; ( 6 ) no hydrolysis of glutamine to glutamate or asparagine to aspartate ; and ( 7 ) applicability to a wide range of neurochemicals . . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
L Glutamate transport by intestinal epithelial cells is an initial step of the entire glutamate metabolism pathway in the gut mucosa . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
It is synthesized in two steps from chorismate and glutamine , the first step being their conversion into glutamate and ADC ( 4 aminodeoxychorismate ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
In addition to impairing Na ( + ) binding , the D367N mutation slowed glutamate transport , as shown by pre steady state kinetic analysis of transport currents , by strongly decreasing the rate of a reaction step associated with glutamate translocation . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
N Acetyl gamma glutamyl phosphate reductase ( AGPR ) catalyzes the third step in an eight step arginine biosynthetic pathway that starts with glutamate . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
The rate limiting step in the biosynthesis of GSH is catalyzed by glutamate cysteine ligase ( GCL ) the activity of which is tightly regulated . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These new drugs impact the first step by inhibiting NAAG peptidase , located on the astrocyte surface , that cleaves glutamate ( Glu ) from the neuropeptide NAAG after it has docked with the astrocyte surface metabotropic Glu receptor 3 ( mGluR 3 ) . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
Through comparison of wild type neelaredoxin with mutants lacking the ferric ion coordinating glutamate , we demonstrate that the remaining step is related to the final coordination of this ligand to the oxidized metal center and kinetically characterize it for the first time , by pulse radiolysis and stopped flow kinetics . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
These currents apparently reflect the reversible sodium coupled glutamate translocation step , because the interaction of the double mutant with potassium is largely impaired . ^^^ Our results suggest that it is the interaction of asparagine 366 and aspartate 368 that is important during the glutamate translocation step . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
An essential step in glutamate neurotransmission is the concentration of glutamate into synaptic vesicles before release from the presynaptic terminal . ^^^
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA
Interacting proteins: P54829 and Q13224 Pubmed SVM Score :0.0
NA