| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| These conformations allow different glutamate residues in the central region of Tcf 4 to form a salt bridge with the same critical charged button , Lys 312 of beta catenin . ^^^ |
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| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| To investigate this issue , we constructed a mutant mouse strain , Apc ( lox / lox ) , in which exon 14 of the tumor suppressor gene adenomatous polyposis coli ( Apc ) is flanked by loxP sequences . i . v . injection of adenovirus encoding Cre recombinase ( AdCre ) at high multiplicity [ 10 ( 9 ) plaque forming units ( pfu ) per mouse ] inactivated the Apc gene in the liver and resulted in marked hepatomegaly , hepatocyte hyperplasia , and rapid mortality . beta Catenin signaling activation was demonstrated by nuclear and cytoplasmic accumulation of beta catenin in the hepatocytes and by the induction of beta catenin target genes ( glutamine synthetase , glutamate transporter 1 , ornithine aminotransferase , and leukocyte cell derived chemotaxin 2 ) in the liver . ^^^ |
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| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| LIN 23 mediated degradation of beta catenin regulates the abundance of GLR 1 glutamate receptors in the ventral nerve cord of C . elegans . ^^^ |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| The observed abnormalities included overexpression of Wnt 1 , Frizzled 1 and 2 receptors , Dishevelled 1 , downregulation of Secreted frizzled related protein 1 , GSK 3beta inactivation , microsatellite instability at the Axin locus as well as induction of beta catenin target genes , such as glutamine synthetase , glutamate transporter 1 , and Wisp 1 . ^^^ |
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| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| We investigated in the rat the effect of axotomy on the different subunits of excitatory glutamatergic AMPA ( GLuR 1 4 ) , NMDA ( NR 1 , NR2A D ) receptors , post synaptic density 95 , vesicular glutamate transporter 2 , beta catenin and cadherin . mRNA levels and / or protein production were analyzed 1 , 3 , 8 , 30 and 60 days after facial nerve axotomy by in situ hybridization and immunohistofluorescence . mRNAs coding for the GLuR 2 4 , NR 1 , NR2A , B , D subunits of glutamatergic receptors and for post synaptic density 95 , were less abundant after axotomy . ^^^ |
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| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P35222 and Q13224 |
Pubmed |
SVM Score :0.0 |
| NA |
|