| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| By contrast , mutations in the myristoylation site and in signaling sites of Nef , ie , sites important for interaction with phosphofurin acidic cluster sorting protein 1 ( PACS 1 ) , Src homology domain 3 ( SH 3 ) domains , and p 21 activated kinase 2 ( PAK 2 ) , were found to be critical for its effect on T cell development . ^^^ |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| The amino terminus contains a polyproline sequence , typically found in Src homology 3 ( SH 3 ) binding domains , and the carboxyl terminus appears to be important for Pak 2 binding . ^^^ |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphorylation mediated superactivation of PAK 2 could be induced by overexpression of different Src kinases or by inhibiting cellular tyrosine phosphatases with pervanadate and could be blocked by the Src kinase inhibitor PP 1 or by mutating the Y 130 residue . ^^^ |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| This novel Nef activity critically depended on its Src homology 3 domain binding motif and required efficient association with Pak 2 activity . ^^^ |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13177 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|