| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| These responses , as well as the downstream effects of AMPK on the phosphorylation of acetyl CoA carboxylase , are largely inhibited by the Ca ( 2+ ) / calmodulin dependent protein kinase kinase ( CaMKK ) inhibitor , STO 609 . ^^^ |
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| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| We now report that there is a significant basal activity and phosphorylation of AMPK in LKB 1 deficient cells that can be stimulated by Ca2+ ionophores , and studies using the CaMKK inhibitor STO 609 and isoform specific siRNAs show that CaMKKbeta is required for this effect . ^^^ |
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| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| Here we show that AMPK is also activated by Ca ( 2+ ) / calmodulin dependent protein kinase kinase ( CaMKK ) . ^^^ Overexpression of CaMKKbeta in mammalian cells increases AMPK activity , whereas pharmacological inhibition of CaMKK , or downregulation of CaMKKbeta using RNA interference , almost completely abolishes AMPK activation . ^^^ |
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| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| The nucleotide induced phosphorylation of AMPK was affected by changes in the concentration of intracellular Ca2+ and by Ca2+ / calmodulin dependent kinase kinase ( CaMKK ) , although most likely it was not dependent on LKB 1 kinase . ^^^ |
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| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| Inhibition of CaMKK with STO 609 or downregulation of CaMKKbeta using RNA interference decreased thrombin induced AMPK activation significantly , indicating that CaMKKbeta was the responsible AMPK kinase . ^^^ |
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| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q13131 and Q96RR4 |
Pubmed |
SVM Score :0.0 |
| NA |
|