| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| Using these antibodies , we showed that indeed mammalian COP 9 and COP 11 , also known as GPS 1 , could be coimmuno precipitated using either of the two specific antibodies , definitively confirming that they are physically part of the same complex . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| Together with the fact that the previously known subunit FUSCA 6 is an Arabidopsis homolog of human GPS 1 , a negative regulator of AP 1 transcription , our data suggest that the COP 9 complex may contain both negative and positive regulators of transcription . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| To understand the structural and functional relationship of the COP 9 signalosome with its subunits , we expressed in wild type and mutant Arabidopsis backgrounds two orthologues of subunit 1 , rice FUS 6 ( rFUS 6 ) and human GPS 1 , and Arabidopsis subunit 8 ( COP 9 ) . ^^^ Human GPS 1 , when expressed in the fus 6 1 null mutant of Arabidopsis , can assemble into a chimeric COP 9 signalosome at low efficiency , demonstrating the structural conservation of the complexes between human and Arabidopsis . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| Here we describe the association between components of the COP 9 signalosome ( CSN 1 , CSN 7 , and CSN 8 ) and two subunits of eukaryotic translation initiation factor 3 ( eIF 3 ) , eIF3e ( p 48 , known also as INT 6 ) and eIF3c ( p 105 ) . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| In this study , we dissected structure and function of the subunit 1 ( CSN 1 or GPS 1 ) of the COP 9 signalosome relative to the complex . ^^^ We conclude that the N terminal half of CSN 1 harbors the activity domain that confers most of the repression functions of CSN 1 while the C terminal half allows integration of the protein into the COP 9 signalosome . . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| CSN 1 N terminal dependent activity is required for Arabidopsis development but not for Rub1 / Nedd8 deconjugation of cullins : a structure function study of CSN 1 subunit of COP 9 signalosome . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| Inositol 1 , 3 , 4 trisphosphate 5 / 6 kinase associates with the COP 9 signalosome by binding to CSN 1 . ^^^ The association of 5 / 6 kinase with the COP 9 signalosome is through an interaction with CSN 1 , which immunoprecipitates with 5 / 6 kinase . ^^^ |
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| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q99627 and Q13098 |
Pubmed |
SVM Score :0.0 |
| NA |
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