| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| Isolation and characterization of death domain ( TNF RI , Fas , TRADD , FADD / MORT 1 , RIP ) and TRAF domain containing proteins ( TRAF 1 , TRAF 2 , TRAF 3 ) have partially bridged a large molecular gap within one of several signaling pathways which originate at the plasma membrane and terminate in the nucleus . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| One site is similar to activated TNFRII in associating with TNFR associated factors TRAF 1 and TRAF 2 , and the second site is similar to TNFRI in associating with the TNFRI death domain interacting protein TRADD . ^^^ |
|
| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| We report here that parallel accumulation of LMP 1 and TRAF 3 , but not TRAF 1 or TRADD , was observed in GSL complexes from lymphoblastoid and LMP 1 positive NPC cells . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| LMP 1 spontaneously aggregates in the plasma membrane and enables two transformation effector sites ( TES 1 and TES 2 ) within the 200 amino acid cytoplasmic carboxyl terminus to constitutively engage the tumor necrosis factor receptor ( TNFR ) associated factors TRAF 1 , TRAF 2 , TRAF 3 , and TRAF 5 and the TNFR associated death domain proteins TRADD and RIP , thereby activating NF kappaB and c Jun N terminal kinase ( JNK ) . ^^^ Mutant and wt LMP 1 proteins were also similar in their constitutive association with TRAF 1 , TRAF 2 , TRAF 3 , TRADD , and RIP . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| TRADD is specific for TRAF 1 and TRAF 2 , which ensures the recruitment of clAPs for the direct inhibition of caspase activation in the signaling complex . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| The critical role of TRAF 1 in the regulation of TRAF 2 dependent JNK signaling is particular to the TRAF binding domain of LMP 1 , since a homologous region in the cytoplasmic tail of CD 40 or the TRADD interacting domain of LMP 1 signal on the JNK axis independently of TRAF 1 status . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| Overexpression of TRAF 1 , however , had no effect on the interaction of TRADD and TRAF 2 , known to be important for tumor necrosis factor receptor 1 ( TNF R 1 ) mediated NF kappaB activation . ^^^ |
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| Interacting proteins: Q15628 and Q13077 |
Pubmed |
SVM Score :0.0 |
| In the normal rat cortex , a portion of TNFR 1 was present in lipid raft microdomains , where it associated with the adaptor proteins TRADD ( TNF receptor associated death domain ) , TNF receptor associated factor 2 ( TRAF 2 ) , the Ser / Thr kinase RIP ( receptor interacting protein ) , TRAF 1 , and cIAP 1 ( cellular inhibitor of apoptosis protein 1 ) , forming a survival signaling complex . ^^^ |
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