| Immunoprecipitates of MST 1 endogenous to LoVo colon cancer cells contain endogenous CNK 1 ; however , no association of these two polypeptides can be detected in a yeast two hybrid assay . ^^^ Deletion of the MST 1 carboxyl terminal segment that mediates its binding to RASSF1A / C eliminates the association of MST 1 with CNK 1 . ^^^ |