| Interacting proteins: Q13043 and P42574 |
Pubmed |
SVM Score :0.0 |
| Further activation of MST 1 by caspase cleavage is best promoted by caspase 3 , although this appears to be unnecessary for signaling and morphological responses . . ^^^ |
|
| Interacting proteins: Q13043 and P42574 |
Pubmed |
SVM Score :0.0 |
| Mst 1 can phosphorylate H2B at S 14 in vitro and in vivo , and the onset of H2B S 14 phosphorylation is dependent upon cleavage of Mst 1 by caspase 3 . ^^^ |
|
| Interacting proteins: Q13043 and P42574 |
Pubmed |
SVM Score :0.0 |
| METHODS AND RESULTS : Treatment of VSMCs with staurosporine induced apoptosis and cleavage of Mst 1 , which is a marker of its activation , as well as activation of caspase 3 . ^^^ Adenovirus mediated overexpression of wild type Mst 1 ( AdMst 1 ) in VSMCs increased apoptotic cells with activation of caspase 3 . ^^^ |
|
| Interacting proteins: Q13043 and P42574 |
Pubmed |
SVM Score :0.0 |
| Knockdown of MST 1 expression by small interfering RNA diminished bortezomib induced apoptosis or caspase 3 activation . ^^^ |
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