| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Using cDNA arrays and serial analysis of gene expression , we found that hypoxia induces up regulation of BNIP 3 and its homologue , Nip 3 like protein 10 . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Sequence comparison of BNIP 3 has indicated that there are several BNIP 3 human homologs of this protein , like BNIP3L , Nix and BNIP 3 . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Among ' BH3 domain only ' members examined ( Bim , Biklk , DP5 / Hrk , Bad , Bid , Noxa , Puma / Bbc3 , Bmf , BNip 3 and BNip3L ) , BNip 3 and Bmf mRNAs increase markedly during differentiation . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Increased DOC 1 expression in SW 48 ( CMV DOC 1 ) was associated with significantly increased expression of proapoptosis components of the caspase cascade ( CASP 7 , CASP 9 ) and bcl2 / bax pathway ( BNIP 3 , BNIP3L , BID ) . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| We found that proapoptotic genes such as BAX , BNIP 3 , and BNIP3L were down regulated in ET MKs together with genes that are components of the mitochondrial permeability transition pore complex , a system with a pivotal role in apoptosis . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| We have , therefore , established three functional categories of BH 3 only human proapoptotic proteins based on their toxicity after expression in budding yeast : directly killing ( tBid ) , sensitizing in Bax / Bcl 2 expressing cells ( Bad or Puma ) , and non toxic ( BNip 3 , BNip3L , and Noxa ) . ^^^ |
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| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Transcriptional induction of HIF 1 dependent genes putatively involved in cell death like BNip 3 and BNip3L was therefore disassociated from hypoxia dependent toxicity . ^^^ |
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| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| METHODS : Reverse transcription polymerase chain reaction ( RT PCR ) was used to examine the expression of five genes associated with hypoxia mediated apoptosis ( PUMA , Caspase 8 [ CASP 8 ] , APAF 1 , BNIP 3 , and BNIP3L ) in a panel of pancreatic cancer cell lines . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Isolation , mapping , and functional analysis of a novel human cDNA ( BNIP3L ) encoding a protein homologous to human NIP 3 . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| A novel adenovirus E1B19K binding protein B 5 inhibits apoptosis induced by Nip 3 by forming a heterodimer through the C terminal hydrophobic region . ^^^ |
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| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| Analysis by cDNA microarray , RT PCR , and Western blot showed that cell death members of Bcl 2 family , Bcl 2 / adenovirus E1B 19 kDa interacting protein 3 ( BNIP 3 ) and its homologue BNIP 3 like ( BNIP3L ) , were upregulated in As ( 2 ) O ( 3 ) induced autophagic cell death . ^^^ Exogenous expression of BNIP 3 , but not BNIP3L , induced autophagic cell death in malignant glioma cells without As ( 2 ) O ( 3 ) treatment . ^^^ |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12983 and O60238 |
Pubmed |
SVM Score :0.0 |
| NA |
|