| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| Casper interacts with FADD , caspase 8 , caspase 3 , TRAF 1 , and TRAF 2 through distinct domains . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NF kappaB antiapoptosis : induction of TRAF 1 and TRAF 2 and c IAP 1 and c IAP 2 to suppress caspase 8 activation . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| Further , immunoprecipitation assays showed that caspase 8 formed triple complex with TRAF 2 and FLASH . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| FADD , Casper , and caspase 8 induced NF kappaB activation are inhibited by dominant negative mutants of TRAF 2 , NIK , IkappaB kinase alpha , and IkappaB kinase beta . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| Apoptotic crosstalk of TNF receptors : TNF R 2 induces depletion of TRAF 2 and IAP proteins and accelerates TNF R 1 dependent activation of caspase 8 . ^^^ Thus , TNF R 2 may compete with TNF R 1 for the recruitment of newly synthesized TRAF 2 bound anti apoptotic factors , thereby promoting the formation of a caspase 8 activating TNF R 1 complex . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| We further demonstrate that the signaling strength induced by a given ligand / receptor interaction is regulated at the level of adaptor protein recruitment , as shown for FADD , caspase 8 , and TRAF 2 . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| Analysis of the native TNF signaling complex revealed the recruitment of RIP , TRADD , and TRAF 2 but not FADD or caspase 8 . ^^^ In an in vitro binding assay , the intracellular domain of TNF R 1 bound TRADD , RIP , and TRAF 2 but did not bind FADD or caspase 8 . ^^^ |
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| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| N terminal fragment of c FLIP ( L ) processed by caspase 8 specifically interacts with TRAF 2 and induces activation of the NF kappaB signaling pathway . ^^^ Moreover , endogenous TRAF 2 interacted specifically with FLIP ( p 43 ) , and the formation of the FLIP ( p 43 ) caspase 8 TRAF 2 tertiary complex was a prerequisite to induction of NF kappaB activation . zVAD fmk prevented the recruitment of TRAF 2 into the death inducing signaling complex . ^^^ Thus , our present results demonstrate that FLIP ( p 43 ) processed by caspase 8 specifically interacts with TRAF 2 and subsequently induces activation of the NF kappaB signaling pathway . . ^^^ |
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| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| BLM exposure had no marked effect on AM expression of TNF R 1 or caspase 8 activation , but significantly increased the expression of TNF R 2 that was accompanied by a rise in c IAP 1 and a decrease in TRAF 2 . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| The analysed factors included TNF alpha , TNFR 1 , TNF receptor associated death domain ( TRADD ) , caspase 3 , caspase 8 , TNF receptor associated factor 2 ( TRAF 2 ) and receptor interactive protein ( RIP ) , all of which are involved in the TNF alpha / TNFR 1 signalling pathway mediated apoptosis . ^^^ The quantitative RT PCR indicated that the infected muscle tissues up regulate the expression of pro apoptosis genes ( TNF alpha , TNFR 1 and TRADD , caspase 3 and caspase 8 ) , and anti apoptosis genes ( TRAF 2 and RIP ) at the beginning of cyst formation . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| The secondary complex retained the DISC components FADD and caspase 8 , but recruited several factors involved in kinase activation by TNF , namely , RIP 1 , TRAF 2 , and NEMO / IKKgamma . ^^^ |
|
| Interacting proteins: Q14790 and Q12933 |
Pubmed |
SVM Score :0.0 |
| DR 3 signal transduction is mediated by a complex of intracellular signaling molecules including TRADD , TRAF 2 , FADD , and FLICE . ^^^ |
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