| Interacting proteins: Q14164 and Q12933 |
Pubmed |
SVM Score :0.0 |
| In vitro kinase assays demonstrate that IKK 1 phosphorylates 1 TRAF in the middle portion that associates with TRAF 2 . ^^^ NF kappaB activation by IKK 1 is significantly blocked by coexpression of the N terminal domain of 1 TRAF , dominant negative TRAF 2 , and dominant negative NIK and IKK beta . ^^^ NF kappaB activation by IKK 1 may be mediated through phosphorylation of 1 TRAF by IKK 1 and subsequent liberation of TRAF 2 . ^^^ |
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| Interacting proteins: Q14164 and Q12933 |
Pubmed |
SVM Score :0.0 |
| We aimed to investigate the dynamics of the NF kappaB signaling pathway in living cells using GFP variants of p 65 NF kappaB , IkappaBalpha , tumor necrosis factor receptor associated factor 2 ( TRAF 2 ) , the NF kappaB inducing kinase ( NIK ) and IkappaB kinases ( IKK 1 and IKK 2 ) . ^^^ |
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| Interacting proteins: Q14164 and Q12933 |
Pubmed |
SVM Score :0.0 |
| TRAIL induced NF kappaB activation was preceded by IkappaBalpha kinase ( IKK ) activation and IkappaBalpha degradation and depended on TRAF 2 , NF kappaB inducing kinase ( NIK ) , IKK 1 , and IKK 2 . ^^^ |
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| Interacting proteins: Q14164 and Q12933 |
Pubmed |
SVM Score :0.0 |
| In mammalian cells , TNAP physically interacts with NIK , TRAF 2 , and TRAF 3 but not IKK 1 or IKK 2 . ^^^ TNAP specifically inhibits NF kappaB activation induced by tumor necrosis factor ( TNF ) alpha , TNF receptor 1 , TRADD , RIP , TRAF 2 , and NIK but does not affect IKK 1 and IKK 2 mediated NF kappaB activation . ^^^ |
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| Interacting proteins: Q14164 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
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