| Interacting proteins: P26842 and Q12933 |
Pubmed |
SVM Score :1.0986689 |
| This revealed that CD 27 directly associates with Traf 2 . 1.0986689^^^ |
|
| Interacting proteins: P26842 and Q12933 |
Pubmed |
SVM Score :0.0 |
| CD 27 , a member of the tumor necrosis factor receptor superfamily , activates NF kappaB and stress activated protein kinase / c Jun N terminal kinase via TRAF 2 , TRAF 5 , and NF kappaB inducing kinase . ^^^ Co transfection of a dominant negative TRAF 2 or TRAF 5 blocked NF kappaB and SAPK / JNK activation induced by CD 27 . ^^^ A kinase inactive mutant NIK blocked CD 27 , TRAF 2 , and TRAF 5 mediated NF kappaB and SAPK / JNK activation . ^^^ These results indicate that TRAF 2 and TRAF 5 are involved in NF kappaB and SAPK / JNK activation by CD 27 , and NIK is a common downstream kinase of TRAF 2 and TRAF 5 for NF kappaB and SAPK / JNK activation . . ^^^ |
|
| Interacting proteins: P26842 and Q12933 |
Pubmed |
SVM Score :0.0 |
| Either TNF receptor associated factor 2 ( TRAF 2 ) or TRAF 3 binds to the CD 27 molecule from the coimmunoprecipitation experiment . ^^^ |
|
| Interacting proteins: P26842 and Q12933 |
Pubmed |
SVM Score :0.0 |
| NA |
|