| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| In this study , we demonstrate that the lectin like transcript 1 ( LLT 1 ) is a physiologic ligand for NKR P1A . ^^^ LLT 1 containing liposomes bind to NKR P1A+ cells , and binding is inhibited by anti NKR P1A mAb . ^^^ Additionally , LLT 1 activates NFAT GFP reporter cells expressing a CD3zeta NKR P1A chimeric receptor ; reciprocally , reporter cells with a CD3zeta LLT 1 chimeric receptor are stimulated by NKR P1A . ^^^ Moreover , LLT 1 on target cells can inhibit NK cytotoxicity via interactions with NKR P1A . . ^^^ |
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| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| In this article , we show that the lectin like transcript 1 ( LLT 1 ) molecule is a ligand for the CD 161 receptor . ^^^ Engagement of CD 161 on NK cells with LLT 1 expressed on target cells inhibited NK cell mediated cytotoxicity and IFN gamma secretion . ^^^ |
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| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| Among the 28 identified NKC gene lineages , 4 , KLRA 1 , KLRB 1 , CLEC2D , and CLEC4A / B / C , have expanded rapidly in rodents only . ^^^ |
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| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| Missing self recognition of Ocil / Clr b by inhibitory NKR P 1 natural killer cell receptors . ^^^ The NKR P1B / D ligand is osteoclast inhibitory lectin ( Ocil ) , also known as Clr b , a member of a previously cloned group of C type lectin related ( Clr ) proteins linked to the NKR P 1 receptors in the mouse NK gene complex ( NKC ) . ^^^ |
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| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| C type lectin domains are not encoded in the MHC of any animal described to date ; therefore , this observation was completely unexpected , particularly given that the chicken has a `` minimal essential MHC . ' ' In this study , we describe the initial characterization of the B NK and B lec genes , and show that they share greatest homology with C type lectin like receptors encoded in the human NK complex ( NKC ) , in particular NKR P 1 and lectin like transcript 1 ( LLT 1 ) , respectively . ^^^ In common with NKR P 1 and LLT 1 , B NK and B lec are located next to each other and transcribed in opposite orientation . ^^^ |
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| Interacting proteins: Q12918 and Q9UHP7 |
Pubmed |
SVM Score :0.0 |
| NA |
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