| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.72017933 |
| Synapse associated protein 102 , a membrane associated guanylate kinase interacting with NR2A but lacking palmitoylation motifs and the ability to cluster , did not protect NR2A from cleavage by calpain . 0.72017933^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| No association was observed between SAP 102 and GluR 1 , a member of the alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionate class of glutamate receptors . ^^^ |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| Postsynaptic localization of N methyl D aspartate type glutamate receptors may be mediated by the synapse associated proteins ( SAPs ) SAP 90 , SAP 102 , and chapsyn 110 . ^^^ |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| We quantitatively defined the contributions of carboxyl terminal residues to binding selectivity of the prototypic interactions of the PDZ domains of postsynaptic density protein 95 ( PSD 95 ) and its homolog synapse associated protein 90 ( SAP 102 ) with the NR2b subunit of the N methyl d aspartate type glutamate receptor . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| Each family of PSD proteins is selective for a given glutamate receptor subtype , the most well characterized being the NMDA receptor binding proteins PSD 93 , PSD 95 , NF L , and SAP 102 . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated dopamine glutamate interactions by measuring the expression of transcripts encoding the subunits for the ionotropic glutamate receptors ( NMDA , AMPA and kainate ) and five NMDAR associated intracellular proteins , PSD 93 , PSD 95 , SAP 102 , NF L and yotiao in the dopaminergic neurons in the substantia nigra pars compacta ( SNc ) of subjects with schizophrenia and a comparison group . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| We review the potential roles in brain plasticity of two membrane associated guanylate kinases ( MAGUKs ) , SAP 102 and PSD 95 , which form a scaffold for the ion passing glutamate receptors at the postsynaptic density , and we consider the known functional significance of these molecules in subunit switching . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| Synapses at P 2 contained substantial levels of NR 1 and NR2B and most GluR associated proteins , including SAP 102 , SynGAP , the chain of proteins from GluRs / SAP102 through GKAP / Shank / Homer and metabotropic glutamate receptors , and the adhesion factors , cadherin , catenin , neuroligin , and Nr CAM . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| Double labeling experiments were performed in order to find out whether SAP 102 is involved with the clustering the N methyl D aspartate ( NMDA ) receptor 2A subunit ( NR2A ) . ^^^ Only a fraction ( approximately 23 % ) of the SAP 102 clusters expressed NR2A , suggesting SAP 102 is also associated with other subunits or receptors . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| PSD 95 ( SAP 90 ) , SAP 102 and Chapsyn 110 ( PSD 93 ) are members of the membrane associated guanylate kinase family , and interact with N methyl D aspartate ( NMDA ) receptor NR2A ( GluRepsilon 1 ) and NR2B ( GluRepsilon 2 ) subunits and with Shaker type K+ channel subunits to cluster into a channel complex . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| From Western blots of hippocampus and immunogold analysis of CA 1 synapses , the high expression of NR2B at P 2 coincides with the high level of SAP 102 at synapses , whereas the later expression of NR2A coincides with that of PSD 93 and PSD 95 . ^^^ To determine whether the changes in PSD 93 / 95 and SAP 102 reflect preferred associations with NR2A and NR2B , respectively , we measured co immunoprecipitation in the adult hippocampus . ^^^ These studies suggest that there is a preference for complexes of NR2A / PSD 93 / 95 and NR2B / SAP 102 . ^^^ |
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| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| In the present study , we performed western blot analysis to determine whether protein levels of NMDA receptor subunits ( NR 1 , NR2A , NR2B ) and associated PSD proteins ( NF L , PSD 95 , SAP 102 ) are altered in schizophrenia . ^^^ |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and Q92796 |
Pubmed |
SVM Score :0.0 |
| NA |
|