| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.59593576 |
| NR3A associates independently with both NR 1 1a and NR2A in the endoplasmic reticulum , but only heteromeric complexes containing the NR 1 1a NMDA receptor subunit are targeted to the plasma membrane . 0.59593576^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Because N methyl D aspartate ( NMDA ) glutamate ionotropic receptors are involved in the occurrence of audiogenic seizures , we investigated by in situ hybridization methods , the expression of the different subunits ( NR 1 , NR2A , NR2B , NR2C ) of this receptor in the central nucleus of the inferior colliculus ( IC ) , a main relay of the auditory pathways . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Application of 500 microM picrotoxin for two days led to decreases in the messenger RNA levels for the N methyl D aspartate receptor subunits , NR2A and NR2B , and for the non N methyl D aspartate receptor subunits , glutamate receptors 1 and glutamate receptors 2 , to about 50 % of the levels seen in control cultures . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The glutamate receptor channels of the N methyl D aspartate ( NMDA ) subtype are composed of different subunits named NR 1 and NR2A D . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Fourteen glutamate receptor subunits were studied : GluR 1 4 ( including flip and flop variants ) , GluR 5 7 , KA 1 & 2 , NR 1 , and NR2A D . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Optimal expression of cloned NMDAR1 / NMDAR2A heteromeric glutamate receptors : a biochemical characterization . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We used in situ hybridization to examine the effect of removal of the glutamatergic input to the striatum by unilateral frontal cortical ablation on the expression of genes encoding subunits from three families of glutamate receptors : N methyl D aspartate receptors ( NMDAR 1 , NMDAR2A , and NMDAR2B ) ; alpha amino 3 hydroxy 5 methyl 4 isoxazolepropionate ( AMPA ) receptors ( GluR 1 4 , flip and flop splice variants ) ; and metabotropic receptors ( mGluR 1 5 ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The expression of NMDA receptor genes ( NR 1 , NR2A B ) was examined by in situ hybridization using oligonucleotide probes , and binding to NMDA receptors assessed using L [ 3H ] glutamate . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Glutamate activated currents ( evoked every 20 s for up to 20 min ) were increased by src and fyn kinases without affecting the desensitization and deactivation kinetics in NR 1 NR2A but the kinases had no effects in NR 1 NR2B , NR 1 NR2C and NR 1 NR2D receptor channels , suggesting that a phosphorylation site in NR2A is targeted . 4 . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Dual in situ hybridization using digoxigenin labeled GnRH cRNA probes and 35S labeled glutamate receptor subunit probes , followed by autoradiography and image analysis were used to measure the KA 2 or NMDAR2A mRNA content in GnRH neurons in 20 to 50 day old female rats which were sacrificed at 08 . 00 or 17 . 00 h . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1 / NR2A NMDA receptors . ^^^ By analysis of 10 mutant NMDA receptors , we now show that residues on the NR2A subunit control glutamate potency in recombinant NR1 / NR2A receptors , without affecting glycine potency . ^^^ One NR2A mutant , NR2A ( T671A ) , had an EC 50 for glutamate 1000 fold greater than wild type and a 255 fold reduced affinity for APV , yet it had single channel openings very similar to those of wild type . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| This antibody ( NR2A / B ) did not cross react with extracts from transfected cells expressing other glutamate receptor subunits , nor did it label non neuronal tissues . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Transcript levels of the NMDA receptor genes NMDAR 1 , NR2A , NR2B , NR2C , and NR2D and a glutamate binding protein ( GBP ) were not altered by kindling . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The N methyl D aspartate ( NMDA ) subtype of ionotropic glutamate receptor is assembled from one NR 1 subunit , expressed in eight splice variants , and four NR 2 subunits ( NR2A D ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The rank order of potency was quinolinic acid < NMDA < homoquinolinic acid < or = glutamate for the NR 1 + NR2A and NR 1 + NR2B combinations whereas for NR 1 + NR2C it was quinolinic acid < < < < homoquinolinic acid < NMDA < or = glutamate . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We further characterized the glutamate site assembled from NR1a , NR2A , and NR2B NMDA receptor subunits using L [ 3H ] glutamate and [ 3H ] CGP 39653 binding assays . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Distribution of the N methyl D aspartate glutamate receptor subunit NR2A in control and amyotrophic lateral sclerosis spinal cord . ^^^ The aim of this study was to examine the distribution of the N methyl D aspartate ( NMDA ) glutamate receptor modulatory subunit NR2A , in control human spinal cord and to examine in parallel the expression of the mRNA in amyotrophic lateral sclerosis ( ALS ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Because native NR2A and NR2B containing receptors are pharmacologically distinct , it should be possible to develop NR2A and NR2B selective glutamate site antagonists . . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Double immunostaining revealed that many of the constitutively expressed Zif 268 positive neurons were GABAergic but very few were cholinergic or neuronal nitric oxide synthase ( nNOS ) positive , and some of the Zif 268 positive neurons were also immunopositive for a glutamate NMDA receptor subunit NR 1 or NR2A . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We have investigated the developmental change in NMDA receptor affinity for both glutamate and glycine in acutely dissociated parietal cortex neurons of the rat , together with the expression during ontogeny of NR2A and NR2B mRNA and protein . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Immunocytochemical localization of metabotropic glutamate receptors ( mGluRs ) and ionotropic glutamate receptors ( NMDA type : NMDAR 1 and NMDAR2A C ; AMPA type : GluR 1 4 ) was performed on sections of rat dorsal horn . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The association of NMDA receptor subunits and CaMKII was assessed by immunoprecipitating PSD proteins with antibodies specific for NR2A / B and CaMKII : CaMKII coprecipitated with NR2A / B and NR 1 but not with other glutamate ionotropic receptor subunits , such as GluR 1 and GluR 2 3 . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Differential effects of electroconvulsive shock on the glutamate receptor mRNAs for NR2A , NR2B and mGluR5b . ^^^ In the dentate gyrus , such treatment elevated the mRNAs for the NMDA subunits NR2A and NR2B , but it reduced the mRNA for the metabotropic glutamate receptor mGlu5b . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The effect of treatment with the D 1 dopamine receptor agonist SKF 38393 on the expression of metabotropic glutamate receptor 1 , 3 , 4 and 5 receptor subtypes and of the glutamate N methyl D aspartate ionotropic receptor subunits NRI , NR2A and NR2B was analysed using in situ hybridization . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here , we investigated the co expression of the neurotrophin 4 / brain derived neurotrophic factor receptor TrkB with the N methyl D aspartate glutamate receptor subunits NR 1 C1 , NR2A and NR2B , on postnatal days 10 and 22 and in the adult rat primary visual cortex . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Western blot analyses using antibodies against different subunits of 2 amino 3 hydroxy 5 methylisoxazole 4 propionic acid ( AMPA ) and N methyl D aspartate ( NMDA ) types of ionotropic glutamate receptors indicate that AMPA receptor subunits ( GluR 1 , GluR2 / 3 , and GluR 4 ) , but not NMDA receptor subunits ( NR 1 and NR2A ) , are proteolytically cleaved after exposure of hippocampal neurons to apoptotic insults , including Abeta , and that the caspase inhibitor zVAD fmk suppresses such cleavage . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Similarly , mRNAs encoding all four alpha amino 3 hydroxy 5 methylisoxazole 4 propionate ( AMPA ) type glutamate receptor subunits and the NR 1 and NR2A , 2B , and 2D subunits of the NMDA type glutamate receptors were detected , suggesting that various combinations of these subunits mediate the cellular response to synaptically released glutamate . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| This neurotoxic effect could be totally prevented by preincubation with an N methyl D aspartate receptor subunit 2B ( NR2B ) specific antagonist , NR2B antibodies , and an unspecific N methyl D aspartate receptor blocker and was partially blocked with an NR2A specific antagonist but not with NR2A antibodies or alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate receptor and metabotropic glutamate receptor antagonists . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Recombinant NR1a / NR2A ( T671A ) N methyl D aspartate ( NMDA ) receptor channels , which carry a point mutation in the putative glutamate binding site that reduces glutamate potency by around 1000 fold , have been expressed in Xenopus laevis oocytes and their single channel properties examined using patch clamp recording techniques . ^^^ The single channel data that we present in this paper support further the idea that the point mutation T671A in the NR2A NMDA receptor subunit affects mainly the ability of glutamate to remain bound to these channels . . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| As demonstrated by chronic blockade of postsynaptic glutamate receptors in vitro , the regulation of NR2A mRNA was strongly dependent on synaptic activity . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| In more severely injured rats , the chronic recovery of detrusor EUS coordination was very incomplete and correlated to decreased innervation of lower motoneurons by descending control pathways and their increased levels of mRNA for glutamate receptor subunits NR2A and GluR 2 . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We have stably transfected HEK 293 cells with recombinant human CaBP in order to determine the influence of this protein upon transient increases in intracellular ionic calcium concentration ( [ Ca ( 2+ ) ] ( 1 ) ) induced either by transient transfection of the NR 1 and NR2A subunits of the N methyl D aspartate ( NMDA ) receptor and brief exposure to glutamate , photolysis of the caged calcium compound NP EGTA , or exposure to the Ca ( 2+ ) ] ionophore 4 Br A 23187 . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| To gain a better understanding about the precise sites of action of glutamate and the subunit compositions of the receptors involved in the glutamatergic neurotransmission in the hypothalamus and septum , in situ hybridization was used with 35S labeled cRNA probes for the different ionotropic receptor subunits , including glutamate receptor subunits 1 4 ( GluR 1 GluR4 ) , kainate 2 , GluR 5 GluR7 , N methyl D aspartate ( NMDA ) receptor 1 ( NMDAR 1 ) , and NMDAR2A NMDAR2D . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| E2F1 ( + / + ) and ( / ) cultures were comparable , in that they contained similar neuronal densities , responded with similar increases in intracellular calcium concentration ( [ Ca ( 2+ ) ] 1 ) to glutamate receptor agonists , and showed similar NMDA receptor subunit mRNA expression levels for NR 1 , NR2A and NR2B . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here we report that the fast desensitization of NR1 / NR2A receptors is caused by ambient zinc , and that a positive allosteric interaction occurs between the extracellular zinc binding site located in the amino terminal domain and the glutamate binding domain of NR2A . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| N methyl D aspartate receptors ( NRs ) are a group of ionotropic glutamate receptors in the brain and they are composed of heteromeric subunits ( NR 1 , NR2A D and NR 3 ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NR 1 ( F639A ) did not alter the agonist potency of glutamate but did produce a leftward shift in the glycine concentration response for receptors containing NR2A and NR2B subunits . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Furthermore , our biochemical experiments showed that enrichment significantly increased protein levels of GluR 1 , NR2B , and NR2A subunits of glutamate receptors in both wild type and NR2B Tg mice . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| When coexpressed with NR 1 and NR2A in heterologous cells , NR3B suppressed glutamate induced current similarly to NR3A . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We have localized regions in the S 1 binding domain of both subunits required for the transmission of allosteric signals from the glutamate binding NR2A subunit to the glycine binding NR 1 subunit . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Parallel measurements of free glutamate and homocysteine levels in the patients blood plasma did not reveal any substantial changes of the given parameters , comparing to indices of autoantibodies to NR2a glutamate receptor . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| These effects of InsP 6 appear to be specific to AMPA receptors , as neither 3H glutamate binding to NMDA receptors nor levels of NR 1 and NR2A subunits in P 2 and P 3 fractions were affected . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here we describe the use of real time quantitative PCR using a fluorescent TaqMan probe , to study the regional differences in expression of glutamate receptor subunit / subtype genes ( NR 1 , NR2A , GluR 2 , KA 2 , mGluR 1 , mGluR 7 ) in the central vestibular system including the vestibular nucleus complex , inferior olive and cerebellar flocculus . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| In normal control animals , regional differences in the expression of several glutamate receptor subunit / subtypes , e . g . , NR 1 and NR2A subunits of the N methyl D aspartic acid ( NMDA ) receptor , GluR 2 and KA 2 subtypes of non NMDA receptors , and mGluR 1 and mGluR 7 metabotropic glutamate receptors , were consistent with previous results from studies using in situ hybridization histochemistry , suggesting that the real time quantitative PCR method was a reliable procedure for evaluation of changes in mRNA expression . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Whereas PS potentiated NMDA , glutamate , and glycine induced currents of NR1 / NR2A and NR1 / NR2B receptors , it was inhibitory at NR1 / NR2C and NR1 / NR2D receptors . 3 . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Identification of a new site in the S 1 ligand binding region of the NMDA receptor NR2A subunit involved in receptor activation by glutamate . ^^^ To further define the amino acids through which glutamate activates the receptor , we generated single site mutations to the NR2A subunit , and expressed them with wild type NR 1 in HEK 293 cells . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The immunohistochemical localization of the NMDA glutamate receptor subunits NR 1 , NR2A , and NR2B was investigated in the rat vestibular periphery at the light and electron microscopy level using specific antipeptide antibodies . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| This approach has allowed us to assess the responses of individual NTS neurones in vivo to ionotropic glutamate receptor agonists and antagonists and then , to determine whether the neurones expressed the glutamate receptor subunits , GLUR 2 , 3 and NMDAR2a , b . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NMDA receptors are ionotropic glutamate receptors assembled of subunits of the NR 1 and of the NR 2 family ( NR2A NR2D ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| In this study , the protein expression levels of several ionotropic glutamate receptor subunits ( N methyl D aspartate ( NMDA ) subunits NR 1 , NR2A , NR2B , and alpha amino 3 hydroxy 5 methyl 4 isoxazoleproprionic acid ( AMPA ) receptor subunits GluR 1 , GluR 2 , GluR 4 ) were quantified in particulate preparations from rat spinal cord at various ages after birth . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Electrophysiological experiments revealed that homoquinolinate activated human recombinant NR1a / NR2A , NR1a / NR2B and NR1a / NR2A / NR2B receptors with EC 50 values of 25 . 2 , 13 . 8 and 9 . 04 micro m , respectively , with intrinsic activities of 148 , 93 . 3 and 125 % , respectively , compared to glutamate ( =100 % ) . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Two regions in the D 1 receptor carboxyl tail can directly and selectively couple to NMDA glutamate receptor subunits NR 1 1a and NR2A . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Delta catenin forms stable complexes with excitatory neurotransmitter receptors including ionotropic N methyl D aspartic acid receptor 2A ( NR2A ) , metabotropic glutamate receptor 1alpha ( mGluR1alpha ) , as well as PSD 95 in vivo . ^^^ Upon glutamate receptor activation , delta catenin becomes down regulated and its association with NR2A and mGluR1alpha in cultured neurons is diminished . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The N methyl d aspartate ( NMDA ) glutamate receptor ( NMDAR ) , long implicated in developmental plasticity , shows decay time kinetics that shorten postnatally as NR2A subunits are added to the receptor . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| N Methyl d aspartate ( NMDA ) receptor subunit 2A ( NR2A ) is an important modulatory component of the NMDA subtype of glutamate receptors . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Mutations in NR2A confirmed that the analogous region controls the pH sensitivity of this subunit and also identified the linker region between the third transmembrane domain ( M 4 ) and the S 2 portion of the NR 2 glutamate binding domain as an additional determinant of proton sensitivity . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The activity of the N methyl D aspartate ( NMDA ) receptor , a subclass of ionotropic glutamate receptor , is modulated by a complex network of phosphorylation and dephosphorylation . 1 investigated the relative extent of tyrosine phosphorylation of NMDA receptor subunit 2A ( NR2A ) and 2B ( NR2B ) subunits in the rat forebrain postsynaptic density ( PSD ) fraction . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| In addition , dorsocaudal brain stem tissue lysates were harvested at 1 h , 6 h , 1 day , 3 days , 7 days , 14 days , and 30 days of SH and IH and analyzed for NR 1 , NR2A , and NR2B NMDA glutamate receptor expression by immunoblotting . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Cultures treated for up to 5 weeks with epidermal growth factor , fibroblast growth factor 2 , retinoic acid , and nerve growth factor displayed neuron like cellular processes and expressed neuronal markers , including the neuronal nuclear antigen NeuN , microtubule associated protein 2 , tau , synaptophysin , alpha ( 1A ) and alpha ( 1B ) calcium channel subunits , NR2A glutamate receptor subunits , and gamma aminobutyric acid . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Activity dependent changes in expression and localization of the largest major isoform of the neural cell adhesion molecule NCAM 180 and three subtypes of glutamate receptors predominantly expressed in the outer part of the molecular layer of the dentate gyrus of adult rats the NMDA receptor NR2A , the AMPA receptor GluR2 / 3 , and the metabotropic glutamate receptor mGluR 1 were investigated using postembedding immunogold labeling , and electron microscopy . ^^^ Thus , changes in synaptic strength are associated with concomitant changes in the expression and distribution of NCAM 180 and glutamate receptors , particularly of the NR2A subtype . . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Glutamate receptor , ionotropic , N methyl D aspartate 2A ( GRIN2A ) gene as a positional candidate for attention deficit / hyperactivity disorder in the 16p13 region . ^^^ The glutamate receptor , ionotropic , N methyl D aspartate 2A ( GRIN2A ) gene that encodes the 2A subunit of the NMDA receptor , resides in this region and a recent study has reported an association between this gene and ADHD . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| In the absence of extracellular calcium , substitution of Arg for Asn 598 ( NR1R ) slowed desensitization by 2 to 3 fold compared with wild type NR1 / NR2A , and glutamate evoked peak current EC 50 and deactivation rate were also affected . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The GRIN2A ( glutamate receptor , ionotropic , N methyl D aspartate 2A ) gene that encodes the N methyl D aspartate receptor subunit 2A ( NMDA2A ) maps to this region of linkage . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Glutamate receptors AMPA GluR2 / 3 and NMDA R2A : NR2A ( NMDAepsilon 1 ) , and GABA ( A ) ( GABA ( A ) Ralpha 1 ) receptors were examined by immunohistochemistry in the cerebral cortex ( frontal cortex ) entorhinal cortex , hippocampus and cerebellar cortex in nine patients with sporadic Creutzfeldt Jakob disease ( CJD ) and eight age matched controls obtained 3 8 h after death . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here we report that covalent modification of NR 1 A652C or the analogous mutation in NR2A , 2B , 2C , or 2D by methanethiosulfonate ethylammonium ( MT SEA ) occurs only in the presence of glutamate and glycine , and that modification potentiates recombinant NMDA receptor currents . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We studied adsorption capacity of 5 latexes to synthetic peptide fragments of mu and delta opioid receptors and to GluR 1 and NR2A subunits of glutamate receptor . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| However , this decrease was not the same for both subunits , resulting in a decrease ( over 30 % ) in the NR2A : NR2B ratio indicating that the NMDAR had temporarily become more sensitive to glutamate and would remain open longer once activated . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The increased levels of extracellular glutamate , NMDA receptor zeta subunit ( NR 1 ) mRNA , NMDA receptor epsilon 1 subunit ( NR2A ) protein , phosphorylated Ca ( 2+ ) / calmodulin kinase 2 ( p CaMKII ) protein , c fos mRNA , c Fos protein , are observed in the specific brain areas of mice and / or rats showing signs of naloxone precipitated withdrawal . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Recordings from outside out patches that contain a single active channel show that NR2A containing receptors have a higher probability of opening at least once in response to a brief synaptic like pulse of glutamate than NR2B containing receptors ( NR2A , 0 . 80 ; NR2B , 0 . 56 ) , a higher peak open probability ( NR2A , 0 . 50 ; NR2B , 0 . 12 ) , and a higher open probability within an activation ( NR2A , 0 . 67 ; NR2B , 0 . 37 ) . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Structural features of the glutamate binding site in recombinant NR1 / NR2A N methyl D aspartate receptors determined by site directed mutagenesis and molecular modeling . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Immunoblotting analysis showed that the NR2A and NR2B subunits of NMDARs were markedly degraded in cultured cortical neurons treated with glutamate , and the degradation of NR 2 subunits was prevented by calpain inhibitors . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Comparative analysis of different competitive antagonists interaction with NR2A and NR2B subunits of N methyl D aspartate ( NMDA ) ionotropic glutamate receptor . ^^^ The antagonist bound conformation of the NR2A and NR2B subunits of N methyl D aspartate ( NMDA ) ionotropic glutamate receptor are modeled using the crystal structure of the DCKA ( 5 , 7 dichloro kynurenic acid ) bound form of the NR 1 subunit ligand binding core ( S1S2 ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Allosteric interaction between zinc and glutamate binding domains on NR2A causes desensitization of NMDA receptors . ^^^ Previous work suggests that fast desensitization of NR1 / NR2A receptors is caused by ambient zinc , and that a positive allosteric interaction occurs between the extracellular zinc binding amino terminal domain and the glutamate binding domain of NR2A . ^^^ Here we demonstrate that this allosteric coupling reflects interactions within the NR2A subunit , and that the affinity of zinc for its binding site is regulated by glutamate binding and not by glycine binding nor by channel pore opening . ^^^ We subsequently use this model to evaluate the effects of extracellular zinc on NR1 / NR2A excitatory postsynaptic currents ( EPSCs ) by simulating the response to a brief synaptic like pulse of glutamate . ^^^ Modelling results show that zinc at a steady state concentration of at least 100 nm has a significant effect on the amplitude of NMDA EPSCs but that concurrent release of 10 microm zinc with synaptic glutamate release has little effect on the amplitude of a single NR1 / NR2A NMDA EPSC . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| We investigated in the rat the effect of axotomy on the different subunits of excitatory glutamatergic AMPA ( GLuR 1 4 ) , NMDA ( NR 1 , NR2A D ) receptors , post synaptic density 95 , vesicular glutamate transporter 2 , beta catenin and cadherin . mRNA levels and / or protein production were analyzed 1 , 3 , 8 , 30 and 60 days after facial nerve axotomy by in situ hybridization and immunohistofluorescence . mRNAs coding for the GLuR 2 4 , NR 1 , NR2A , B , D subunits of glutamatergic receptors and for post synaptic density 95 , were less abundant after axotomy . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here we report crystal structures of the ligand binding core of NR2A with glutamate and that of the NR 1 NR2A heterodimer with glutamate and glycine . ^^^ The NR2A glutamate complex defines the determinants of glutamate and NMDA recognition , and the NR 1 NR2A heterodimer suggests a mechanism for ligand induced ion channel opening . ^^^ |
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| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| While there were no alterations in the glutamate sensitivity , channel open probability or the single channel conductance of the receptor , a crosslinking assay demonstrated that the NR 1 and NR2A subunits of NMDA receptors were preferentially retained in the cytoplasm after SD , indicating that SD alters NMDAR surface expression . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The NR2A pre M 1 region , the linker between the glutamate binding domain and the channel pore , plays a critical role in desensitization . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Sections were processed and analyzed for [ 3H ] glutamate binding to NMDA receptors using receptor autoradiography and for mRNA for the zeta 1 ( NR 1 ) , epsilon 1 ( NR2A ) , and epsilon 2 ( NR2B ) subunits of the NMDA receptor using in situ hybridization . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Mutation of Ser 670 to glycine ( S670G ) in NR2A reduced the potency of glutamate by 124 fold . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Applying semi quantitative immunoblotting , we found that in the whole tetanized hippocampus , synaptic expression of the N methyl D aspartate and alpha amino 3 hydroxyl 5 methyl 4 isoxazole propionate receptor subunits ( NR 1 , NR2A , glutamate receptor 1 ) and their associated partners , e . g . synaptic associated protein 97 , postsynaptic density protein 95 , alpha subunit of Ca2+ / calmodulin dependent protein kinase 2 , neuronal nitricoxide synthase , increased 180 min post high frequency stimulation . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The IC 50 values for NVP AAM 077 acting at NR1 / NR2A NMDA receptors were , as expected , dependent on the glutamate concentration used to evoke responses , being 31 + / 2 nM ( with glutamate at its EC 50 concentration ) and 214 + / 10 nM ( at 10 times the EC 50 concentration ) . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Among the 18 ionotropic glutamate receptor subunits identified in the mammalian central nervous system , five ( delta 1 , delta 2 , GluR 7 , chi 2 and NR3A , formerly called NMDAR L or chi 1 ) reportedly fail to form functional ion channels in heterologous expression systems . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NMDA receptor subunit gene expression in the rat brain : a quantitative analysis of endogenous mRNA levels of NR1Com , NR2A , NR2B , NR2C , NR2D and NR3A . ^^^ The present study was undertaken to examine the level of gene expression for the NR 1 , NR2A , NR2B , NR2C , NR2D and NR3A receptor subunits in isolated regions of rat brain using the nuclease protection assay . ^^^ The relative proportions of the other subunits ( NR2A D and NR3A ) varied widely , suggesting that NMDA receptor composition is unique to each region of the brain . . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Remarkably , when co expressed in Xenopus oocytes , NR3A or NR3B co assembles with NR 1 to form excitatory glycine receptors that are unaffected by glutamate or NMDA , and inhibited by D serine , a co activator of conventional NMDARs . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Using the anti NR3A antibody in immunoprecipitation studies , we find that 9 . 7 + / 0 . 8 % of NR 1 , 8 . 7 + / 1 . 8 % of NR2A , and 5 . 0 + / 0 . 6 % of NR2B are associated with NR3A at postnatal day 10 . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| The NMDA subtype of glutamate receptors are heteromeric complexes comprised of multiple subunits encoded by at least seven different genes ( NR 1 , NR2A 2D and NR3A 3B ) , and differential expression of these subunits alters the pharmacological and electrophysiological properties of NMDA receptors . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Because structural heterogeneity might be the basis for physiological properties , we examined the expression of six NMDA receptor subunits ( NMDAR 1 , NR2A 2D , and NR3A ) plus eight NMDR 1 splice variants in pre Botzinger complex , hypoglossal and , for comparison , neurons from the nucleus of the solitary tract in young rats using single cell multiplex RT PCR . ^^^ Expression of NR2A , NR2B , and NR2D was observed in all three cell types while NR3A was much more abundant in pre Botzinger complex interneurons , which belong to the rhythm generator of respiratory activity . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NR 1 , NR2A , NR2B , NR2C , NR2D and NR3A subunits showed clustered expression in cell processes , but NR3B was absent . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| Here , a soluble NR3A ligand binding domain ( NR3A S1S2 ) was constructed based on amino acid sequence alignments with other glutamate receptor ion channels and is expressed in Escherichia coli . ^^^ Glutamate , which binds to NR 2 subunits , also binds to NR3A , but with very low affinity ( Kd = 9 . 6 mm ) ; in contrast , binding of glutamate to NR 1 was not detectable even at a 300 mm concentration . ^^^ |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q8TCU5 and Q12879 |
Pubmed |
SVM Score :0.0 |
| NA |
|