| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.50684244 |
| Tyrosine phosphorylation of NR2A and interaction of NR2A with Src and Pyk 2 in hippocampus induced by brain ischemia and reperfusion ( I / R ) were determined by immunoprecipitation and immunoblot ( ting ) . 0.50684244^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.64043033 |
| Intracerebroventricular infusion of PSD 95 antisense oligonucleotides ( every 24 h for 3 days before ischemia ) , but not missense oligonucleotides or vehicle , not only markedly decreased the protein level of PSD 95 but also attenuated the elevated tyrosine phosphorylation of NR2A and interactions of Src and Fyn with NR2A induced by 6 h of reperfusion following ischemia in the hippocampus . 0.64043033^^^ Suppression of postsynaptic density protein 95 expression attenuates increased tyrosine phosphorylation of NR2A subunits of N methyl D aspartate receptors and interactions of Src and Fyn with NR2A after transient brain ischemia in rat hippocampus . 0.50461699^^^ The effects of suppression of postsynaptic density protein 95 ( PSD 95 ) expression on the increased tyrosine phosphorylation of N methyl D aspartate receptor subunit NR2A and interactions of Src and Fyn with NR2A after brain ischemia were investigated by immunoprecipitation and immunoblotting . 0.50347575^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| The morphological properties of this mutant src could be accounted for entirely by a single mutation in the SH 3 domain ( lysine 106 to glutamate ) . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Heteromeric NMDA receptor channels were transiently expressed in human embryonic kidney ( HEK ) 293 cells and glutamate ( 100 microM ) activated whole cell currents ( 500 ms ) were studied when tyrosine kinases of the src gene family were included in the pipette solution . 3 . ^^^ Glutamate activated currents ( evoked every 20 s for up to 20 min ) were increased by src and fyn kinases without affecting the desensitization and deactivation kinetics in NR 1 NR2A but the kinases had no effects in NR 1 NR2B , NR 1 NR2C and NR 1 NR2D receptor channels , suggesting that a phosphorylation site in NR2A is targeted . 4 . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Glutamate and lysine residues that are highly conserved in LBDs of nuclear receptors form a ' charge clamp ' that contacts backbone atoms of the LXXLL helices of SRC 1 . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Tocotrienol potently inhibits glutamate induced pp 60 ( c Src ) kinase activation and death of HT 4 neuronal cells . ^^^ Activation of pp 60 ( c Src ) kinase and phosphorylation of ERK were observed in response to glutamate treatment . ^^^ Nanomolar amounts of alpha tocotrienol , but not alpha tocopherol , blocked glutamate induced death by suppressing glutamate induced early activation of c Src kinase . ^^^ Overexpression of kinase active c Src sensitized cells to glutamate induced death . ^^^ Tocotrienol treatment prevented death of Src overexpressing cells treated with glutamate . alpha Tocotrienol did not influence activity of recombinant c Src kinase suggesting that its mechanism of action may include regulation of SH domains . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| A recently identified family of multidomain proteins termed Src homology 3 domain and ankyrin repeat containing ( Shank ) , also known as proline rich synapse associated protein / somatostatin receptor interacting protein , plays a central role in organizing the subsynaptic scaffold by interacting with several synaptic proteins including the glutamate receptors . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphorylation of ionotropic glutamate receptors by Fyn or Src differentially modulates their susceptibility to calpain and enhances their binding to spectrin and PSD 95 . ^^^ To test whether and how tyrosine phosphorylation of glutamate ionotropic receptor subunits modulates calpain susceptibility , synaptic membranes were phosphorylated by Fyn or Src , two members of the Src family tyrosine kinases . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| We have examined the expression and activity of focal adhesion tyrosine phosphatases [ Src homology 2 domain phosphatase ( SHP 2 ) , protein tyrosine phosphatase ( PTP 1B ) , and PTP proline , glutamate , serine , and threonine sequences ( PEST ) ] during normal nephrogenesis and in cystic kidneys from bcl 2 / mice . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Dual action of estrogen on glutamate induced calcium signaling : mechanisms requiring interaction between estrogen receptors and src / mitogen activated protein kinase pathway . ^^^ Further , the CEE potentiated glutamate response was mediated by a src tyrosine kinase , as the tyrosine kinase inhibitor PP 2 blocked the potentiation induced by CEE and neurons treated with CEE displayed increased phosphorylated tyrosine . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Src kinase regulation of N methyl D aspartate ( NMDA ) subtype glutamate receptors in the central nervous system ( CNS ) has been found to play an important role in processes related to learning and memory , ethanol sensitivity and epilepsy . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Metabotropic glutamate receptor 1 induced upregulation of NMDA receptor current : mediation through the Pyk2 / Src family kinase pathway in cortical neurons . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| The increase in NR2B tyrosine phosphorylation was abolished by intrathecal pretreatment with genistein , a tyrosine kinase inhibitor ; PP 2 , an Src family tyrosine kinase inhibitor ; AIDA , a group 1 metabotropic glutamate receptor antagonist ; L 733 , 060 , an NK 1 tachykinin receptor antagonist , and chelerythrine , a protein kinase C inhibitor . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| At hippocampal synapses , induction of long term potentiation requires the Pyk2 / Src signaling pathway , which up regulates the activity of N methyl d aspartate type glutamate receptors . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| A Src kinase inhibitor , SU 6656 , and an NR2B antagonist , ifenprodil , partially blocked glutamate excitotoxicity . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| This work is based on our striking evidence that , in neuronal cells , nanomolar concentrations of alpha tocotrienol , but not alpha tocopherol , block glutamate induced death by suppressing early activation of c Src kinase ( Sen , C . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| A role for Src kinase in the regulation of glutamate release from rat cerebrocortical nerve terminals . ^^^ In order to investigate the role of Src kinase on neurotransmmiter glutamate release , we studied the effect of PP 2 , an Src family tyrosine kinase specific inhibitor , on depolarization induced glutamate release . ^^^ These results suggest that protein phosphorylation effected by Src may increase presynaptic Ca2+ channel activity and in so doing enhance evoked glutamate release . ^^^ Inhibition of Src may represent a neuroprotective effect to limit the release of glutamate . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1 / 2 and Akt / PKB but not JNK in cultured striatal neurones . ^^^ This revealed a Src dependent phosphorylation of a focal adhesion kinase ( FAK ) p 85 complex on glutamate stimulation . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| It has been indicated that Pyk2 / Src signaling pathway is involved in modulation of N methyl D aspartate type ( NMDA ) glutamate receptor activity . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| In the present study , we tested the following hypotheses : 1 ) rat carotid artery injury induces the expression of PTP 1B , Src homology 2 domain phosphatase ( SHP 2 ) , and PTP proline , glutamate , serine , and threonine sequence ( PEST ) protein ; and 2 ) polypeptide growth factors as well as ANG 2 increase the levels of tyrosine phosphatases in cultured rat aortic smooth muscle cells . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Here , we show that in rats with Freund ' s adjuvant induced inflammation , the increased dorsal horn NR2B tyr P is blocked by group 1 metabotropic glutamate receptor ( mGluR ) antagonists [ 7 ( hydroxyimino ) cyclopropa [ b ] chromen 1a carboxylate ethyl ester ( CPCCOEt ) and 2 methyl 6 ( phenylethynyl ) pyridine ( MPEP ) , by the Src inhibitor CGP 77675 , but not by the MAP kinase inhibitor 2 ' amino 3 ' methoxyflavone . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Inasmuch as Src kinase is capable of upregulating the NMDA subtype of glutamate receptors , we determined whether Src kinase participated in PbTx 2 induced Ca ( 2+ ) influx . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| BACKGROUND AND PURPOSE : The current work is based on our previous finding that in neuronal cells , nmol / L concentrations of alpha tocotrienol ( TCT ) , but not alpha tocopherol ( TCP ) , blocked glutamate induced death by suppressing early activation of c Src kinase and 12 lipoxygenase . ^^^ Pharmacological as well as genetic approaches revealed that 12 Lox is rapidly tyrosine phosphorylated in the glutamate challenged neuron and that this phosphorylation is catalyzed by c Src . 12 Lox deficient mice were more resistant to stroke induced brain injury than their wild type controls . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Src kinase is widely expressed in the brain and its inhibition with PP 2 has previously been shown to depress depolarization evoked glutamate release from rat cerebrocortical synaptosomes by reducing voltage dependent Ca2+ entry . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| We have studied the role of src family tyrosine kinases in regulating synaptic transmitter release from rat brain synaptosomes by using two assays that measure different aspects of synaptic vesicle exocytosis : glutamate release ( that directly measures exocytosis of vesicle contents ) and release of FM 2 10 styryl dye ( that is proportional to the time the synaptic vesicle is fused to the plasma membrane ) . ^^^ The src family selective inhibitor , PP 1 ( 10 microM ) , increased KCl and 0 . 3 mM 4AP evoked Ca2+ dependent release of glutamate , but had little effect upon exocytosis evoked by 1mM 4AP . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| The non receptor tyrosine kinase Src , phosphatidylinositol 3 kinase , protein kinase B and the mammalian target of rapamycin are mediators of the glutamate effect . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| These results suggest that PSD 95 is critical for regulation of NMDA receptor activity by Fyn and other Src family PTKs , serving as a molecular scaffold for anchoring these PTKs to NR2A . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Although the carboxy ( C ) terminal domain of the NR2A subunit contains potential tyrosine phosphorylation sites , the mechanisms by which Src modulates synaptic plasticity and NMDA receptor currents is not fully understood . ^^^ Here we present evidence from NR 1 mutants and splice variants that Src potentiates NMDA receptor currents by reducing the tonic inhibition of receptors composed of NR 1 and NR2A subunits by extracellular zinc . ^^^ Using site directed mutagenesis , we have identified three C terminal tyrosine residues of NR2A that are required for Src ' s modulation of the zinc sensitivity of NMDA receptors . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| The ischemia induced increase in the interaction of NR2A and NR2B with the SH 2 domains of Src and Fyn suggests a possible mechanism for the recruitment of signaling proteins to the PSD and may contribute to altered signal transduction in the postischemic hippocampus . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Identification of mouse NMDA receptor subunit NR2A C terminal tyrosine sites phosphorylated by coexpression with 5 Src . ^^^ Using antiphosphotyrosine antibody PY 20 , we find that on expression in HEK cells , 5 Src and Fyn cause detectable tyrosine phosphorylation only of NR2A . ^^^ Because a stronger signal was produced by the constitutively active 5 Src , the general region of 5 Src phosphorylation was delimited by expression of a series of truncation mutants of NR2A . ^^^ Two of these sites , Y 1292 and Y 1387 , were suggested to control current modulation by Src in previous studies of HEK cells expressing NR1 / NR2A . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NMDA receptor activation results in tyrosine phosphorylation of NMDA receptor subunit 2A ( NR2A ) and interaction of Pyk 2 and Src with NR2A after transient cerebral ischemia and reperfusion . ^^^ In this study , effect of ischemia and reperfusion ( I / R ) on tyrosine phosphorylation of NMDA receptor subunit 2A ( NR2A ) and the interaction of two tyrosine kinases , Src and Pyk 2 , with NR2A was investigated . ^^^ Src and Pyk 2 co immunoprecipitated with NR2A and the binding increased after I / R , which also reached a peak at 6 h of reperfusion . ^^^ These data show that NR2A , Src and Pyk 2 might form a protein complex in vivo and the interaction suggests a possible mechanism of signal transduction in the postischemic hippocampus . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| We have investigated the tyrosine phosphorylation of NMDA receptor subunits NR2A and NR2B by exogenous Src and Fyn and compared this to phosphorylation by tyrosine kinases associated with the postsynaptic density ( PSD ) . ^^^ Src and Fyn phosphorylated similar sites in NR2A and NR2B , tryptic peptide mapping identifying seven and five major tyrosine phosphorylated peptides derived from NR2A and NR2B , respectively . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Our results demonstrate that zinc increases NMDA receptor function via Src family tyrosine kinase mediated increases of NR2A and 2B tyrosine phosphorylation . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Recent studies have indicated that tyrosine phosphorylation of NMDA receptor subunit 2A ( NR2A ) by Src family kinases ( Src , Fyn , etc . ) up regulates NMDA receptors activity and postsynaptic density protein 95 kDa ( PSD 95 ) may mediate the regulation . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| We have shown that an Src family kinase Fyn phosphorylates NR2A and NR2B subunits of the NMDA receptor . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| In this study , we investigated the effects of protein tyrosine kinase ( PTK ) and protein tyrosine phosphatase ( PTP ) on the tyrosine phosphorylation of N methyl D aspartate receptor subunit 2A ( NR2A ) and the interactions among NR2A , postsynaptic density protein 95 ( PSD 95 ) , Fyn / Src after brain ischemia / reperfusion ( I / R ) . ^^^ The following results were observed : ( 1 ) the increase in tyrosine phosphorylation of NR2A induced by I / R was suppressed by genistein , an inhibitor of PTK , but was further enhanced by sodium orthovanadate , an inhibitor of PTP , which were administered to the SD rats 20 min before ischemia . ( 2 ) Importantly , genistein and sodium orthovanadate increased and decreased the interactions involving NR2A , PSD 95 , Fyn and Src , respectively . ^^^ These results demonstrated that PTK and PTP were involved in regulating tyrosine phosphorylation of NR2A through changing the interaction among NR2A , PSD 95 , Fyn / Src . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphorylation of the NR2A and NR2B subunits of the N methyl d aspartate ( NMDA ) receptor by Src protein tyrosine kinases modulates receptor channel activity and is necessary for the induction of long term potentiation ( LTP ) . ^^^ Cotransfection of H Ras and Src inhibited Src activity and decreased NR2A tyrosine phosphorylation . ^^^ Treatment of rat brain slices with Tat H Ras depleted NR2A from the synaptic membrane , decreased endogenous Src activity and NR2A phosphorylation , and decreased the magnitude of hippocampal LTP . ^^^ We suggest that H Ras negatively regulates Src phosphorylation of NR2A and retention of NR2A into the synaptic membrane leading to inhibition of NMDA receptor function . ^^^ This mechanism is specific for Src and NR2A and has implications for studies in which regulation of NMDA receptor mediated LTP is important , such as synaptic plasticity , learning , and memory and addiction . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Since brain ischemia results in NMDA receptor over excitation and Src family protein tyrosine kinase mediated tyrosine phosphorylation of NMDA receptor subunit 2A ( NR2A ) enhances NMDA receptor activity , we examined the effects of lithium on tyrosine phosphorylation of NR2A and its interactions with Src and Fyn ( two members of the Src family of protein tyrosine kinases ) mediated by PSD 95 ( postsynaptic density protein 95 kDa ) after 6 h of reperfusion following 15 min of ischemia ( I / R ) , which was induced by occlusion of the four vessels in Sprague Dawley rats . ^^^ After abdominal injection of LiCl ( 2 mg / kg ) for 7 days , the data showed that together with the significant decrease in I / R induced tyrosine phosphorylation of NR2A , the interactions of NR2A with Src and Fyn mediated by PSD 95 were also decreased significantly . ^^^ However , lithium pretreatment did not alter the total protein levels of NR2A , Src , Fyn and PSD 95 . ^^^ These results suggest that the inhibition of NR2A tyrosine phosphorylation and its interactions with Src and Fyn mediated by PSD 95 may contribute to the lithium induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Following ischemia , tyrosine phosphorylation of NR2A and NR2B and activated Src family kinases ( SFKs ) and Pyk 2 were increased in post synaptic densities ( PSDs ) . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Tyrosine phosphorylation of the NMDA receptor subunit NR2A by Src or Fyn has been implicated in the up regulation of NMDA receptor activity . ^^^ In order to investigate the possible mechanism of the neuroprotective action of SY 21 , we examined the effects of SY 21 on the ischemia / reperfusion induced increases in tyrosine phosphorylation of the NMDA receptor subunit 2A ( NR2A ) and on the interactions involving NR2A , PSD 95 and Src / Fyn . ^^^ Also , SY 21 attenuated the increased interactions involving NR2A , PSD 95 , Fyn and Src . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| I / R led to increases of tyrosine phosphorylation of NR2A and interaction of Pyk 2 and Src kinase with NR2A after 6 h of reperfusion . ^^^ The antisense also inhibited the increased auto phosphorylation of Pyk 2 and Src kinase , while the protein expression of NR2A or Src kinase had no obvious change under the above conditions . ^^^ The data suggested that Pyk 2 may be involved in facilitating NR2A tyrosine phosphorylation by Src kinase after I / R . . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Two different models of brain ischemia were used to examine the evoked changes in the tyrosine phosphorylation of NMDA receptor subunits 2A and 2B ( NR2A and NR2B ) , as well as their interactions with non receptor tyrosine kinases ( NRTKs : FAK , PYK 2 Src ) , and PSD 95 protein . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Both GRGDSP and fibronectin caused rapid Src kinase dependent increases in tyrosine phosphorylation of NMDA receptor subunits NR2A and NR2B in synaptoneurosomes and acute hippocampal slices . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| Our previous investigation has shown that postsynaptic density protein 95 ( PSD 95 ) is critical for the Src family kinases mediated tyrosine phosphorylation of N methyl d aspartate receptor subunit 2A ( NR2A ) in the postischemic hippocampus . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| We further observed that ethanol exposure results in NR2A endocytosis through the activation of H Ras and the inhibition of the tyrosine kinase Src . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| In vitro studies with RVM slices show that BDNF induces tyrosine phosphorylation of the NMDAR NR2A subunit in RVM via a signal transduction cascade involving IP ( 3 ) , PKC , and Src . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| In the first presentation , Dorit Ron presented data showing how activation of Fyn or Src tyrosine kinases differentially regulated the cell surface expression and activity of NR2A and NR2B containing NMDA receptors . ^^^ |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q12879 and P12931 |
Pubmed |
SVM Score :0.0 |
| NA |
|