| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.60797568 |
| Therefore , at least in this way , the pioneer round of translation is distinct from steady state translation . eIF4GI , poly ( A ) binding protein ( PABP ) 1 , eIF 3 , eIF4AI , and eIF2alpha coimmunopurify with both CBP 80 and eIF4E , which suggests that each factor functions in both modes of translation . 0.60797568^^^ |
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| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| A previously undetected , conserved region predicted to form an alpha helical domain is delineated in the initiation factor eIF4G , in Nonsense mediated mRNA decay 2 protein ( NMD2 / UPF2 ) , in the nuclear cap binding CBP 80 , and in other , poorly characterized proteins , which is named the NIC ( NMD 2 , eIF4G , CBP 80 ) domain . ^^^ |
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| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| We show that baculovirus produced CBP 80 and CBP 20 independently interact with eIF4GI . ^^^ |
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| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| IF4G and CBP 80 share a common origin and similar domain organization : implications for the structure and function of eIF4G . ^^^ Here , we present evidence that eIF4G and the large subunit of the nuclear cap binding complex , CBP 80 , share a common origin and domain structure . ^^^ We propose that the organization of the individual domains in eIF4G and CBP 80 could also be conserved . ^^^ The structure of CBP 80 , in complex with the nuclear cap binding protein CBP 20 , is used to build a model for the mutual orientation of the domains in eIF4G and their interactions with other factors . ^^^ The organization of the CBP 80 CBP20 complex suggests how the activity of eIF4G in translation initiation could be regulated through a dynamic network of overlapping intra and intermolecular interactions centered around the eIF4G HEAT domains . . ^^^ |
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| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q09161 and Q04637 |
Pubmed |
SVM Score :0.0 |
| NA |
|