| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| BMX , a novel nonreceptor tyrosine kinase gene of the BTK / ITK / TEC / TXK family located in chromosome Xp22 . 2 . ^^^ Bmx cDNA comprises a long open reading frame of 675 amino acids , containing one SH 3 , one SH 2 and one tyrosine kinase domain , which are about 70 % identical with Btk , Itk and Tec and somewhat less with Txk tyrosine kinase sequences . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Btk along with Tec , Itk and Bmx belong to a distinct family of protein kinases . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec protein tyrosine kinase family includes Btk , Itk / Tsk / Emt , Tec , Rlk / Txk , and Bmx which are involved in signals mediated by various cytokines or antigen receptors . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Btk is a member of the Tec family of nonreceptor protein tyrosine kinases that includes Bmx , Itk , Tec , and Txk . ^^^ Itk and Tec have recently been shown to reconstitute PLCgamma 2 dependent signaling in Btk deficient human cells , but it is not known whether the atypical Tec family members , Bmx and Txk , can reconstitute function . ^^^ We show that in common with Itk and Tec , Bmx reconstituted PLCgamma 2 dependent responses including calcium mobilization , extracellular signal regulated kinase ( ERK ) mitogen activated protein kinase ( MAPK ) activation , and apoptosis . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec protein tyrosine kinase ( PTK ) family includes Btk , Itk / Tsk / Emt , Tec , Rlk / Txk and Bmx , which are involved in signals mediated by various surface receptors . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Tec , Btk , Itk , Bmx , and Txk constitute the Tec family of protein tyrosine kinases ( PTKs ) , a family with the distinct feature of containing a pleckstrin homology ( PH ) domain . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The structures for the PH domains of Bmx , Itk , and Tec were modelled based on Btk structure . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec protein kinase family includes Btk , Itk , Tec , Rlk and Bmx , which are critically involved in signals mediated by various cytokines and antigen receptors . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Btk along with Tec , Itk , Bmx and Txk belong to a distinct family of protein kinases . ^^^ |
|
| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec family of cytoplasmic tyrosine kinases : mammalian Btk , Bmx , Itk , Tec , Txk and homologs in other species . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Tec is the prototypic member of a family of intracellular tyrosine kinases that includes Txk , Bmx , Itk , and Btk . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Tec family tyrosine kinases , Bruton ' s tyrosine kinase ( Btk ) , Itk , Bmx , Tec , and Txk , are multi domain proteins involved in hematopoietic signaling . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The major phosphorylation sites were identified as conserved tyrosines , for Itk Y 180 and for Bmx Y 215 , both sites being homologous to the Y 223 site in Btk . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec protein tyrosine kinase is the founding member of a family that includes Btk , Itk , Bmx , and Txk . ^^^ In contrast , overexpression of Btk , Itk , or Bmx does not induce NFAT activation . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| Members of the Tec kinase family ( Bmx , Btk , Itk , Rlk and Tec ) are primarily expressed in the hematopoietic system and form , after the Src kinase family , the second largest class of non receptor protein tyrosine kinases . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| The Tec family of protein tyrosine kinases ( PTKs ) , that includes Tec , Itk , Btk , Bmx , and Txk , plays an essential role in phospholipase Cgamma ( PLCgamma ) activation following antigen receptor stimulation . ^^^ |
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| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P51813 and Q08881 |
Pubmed |
SVM Score :0.0 |
| NA |
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