Interacting proteins: Q08211 and Q9UBU9 |
Pubmed |
SVM Score :0.59467142 |
RHA binds to Sam 68 and to Tap both in vivo and in vitro . 0.59467142^^^ |
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Interacting proteins: Q08211 and Q9UBU9 |
Pubmed |
SVM Score :0.0 |
Two cellular proteins , RNA helicase A ( RHA ) and Tip associated protein ( Tap ) were identified as binding to CTE and were proposed to function as CTE co factors ( 1 , 2 ) . ^^^ The in vitro binding of RHA to Tap is direct and independent of either CTE or the nuclear transport domain of RHA . ^^^ The removal of the first 60 amino acids of Tap significantly diminishes the binding to RHA . ^^^ A transdominant mutant of Tap inhibited RHA mediated up regulation of CTE function in mammalian cells . ^^^ The nuclear transport domain of RHA also interfered with Tap mediated transactivation of the CTE function in quail cells , in which the function of CTE is dependent on the expression of a functional human Tap cDNA . . ^^^ |
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Interacting proteins: Q08211 and Q9UBU9 |
Pubmed |
SVM Score :0.0 |
NA |
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