| Interacting proteins: Q7Z465 and Q07960 |
Pubmed |
SVM Score :0.0 |
| BNIPL 2 , a novel homologue of BNIP 2 , interacts with Bcl 2 and Cdc42GAP in apoptosis . ^^^ We report here the identification of a novel member of BNIPL family , designated Bcl 2 / adenovirus E1B 19kDa interacting protein 2 like 2 ( BNIPL 2 ) , which interacts with Bcl 2 and Cdc42GAP . ^^^ We found that the human BNIPL 2 shares homology to human BNIP 2 and also possesses a BNIP 2 and Cdc42GAP homology ( BCH ) domain . ^^^ Deletion experiments indicated that the BCH domain of BNIPL 2 is critical for its interactions with the Bcl 2 and Cdc42GAP and also for its cell death inducing function . ^^^ |
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| Interacting proteins: Q7Z465 and Q07960 |
Pubmed |
SVM Score :0.0 |
| Bcl 2 / adenovirus E1B 19 kDa interacting protein 2 like 1 ( BNIPL 1 ) is a novel human protein identified in our laboratory , which can interact with Bcl 2 and Cdc42GAP and induce apoptosis via the BNIP 2 and Cdc42GAP homology ( BCH ) domain . ^^^ |
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| Interacting proteins: Q7Z465 and Q07960 |
Pubmed |
SVM Score :0.0 |
| The BNIP S gene encodes two protein isoforms ; the longer protein ( BNIP Salpha ) contains a complete BNIP 2 and Cdc42GAP Homology ( BCH ) domain , a novel protein domain that we recently identified , whereas its shorter variant ( BNIP Sbeta ) lacks the full BCH domain as a result of an alternative RNA splicing that introduces a nonsense intron . ^^^ |
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