| Interacting proteins: Q96MU7 and Q07666 |
Pubmed |
SVM Score :0.0 |
| The interaction and colocalization of Sam 68 with the splicing associated factor YT 521 B in nuclear dots is regulated by the Src family kinase p 59 ( fyn ) . ^^^ Here , we describe a tyrosine phosphorylated nuclear protein , YT 521 B , and show that it interacts with the nuclear transcriptosomal component scaffold attachment factor B , and the 68 kDa Src substrate associated during mitosis , Sam 68 . ^^^ The Src family kinase p 59 ( fyn ) mediated tyrosine phosphorylation of Sam 68 negatively regulates its association with YT 521 B , and overexpression of p 59 ( fyn ) dissolves nuclear dots containing YT 521 B . ^^^ Together , our data indicate that YT 521 B and Sam 68 may be part of a signal transduction pathway that influences splice site selection . . ^^^ |
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| Interacting proteins: Q96MU7 and Q07666 |
Pubmed |
SVM Score :0.0 |
| Here , we demonstrate that rSLM 1 interacts with itself , scaffold attachment factor B , YT 521 B , SAM 68 , rSLM 2 , SRp30c , and hnRNP G . rSLM 1 regulates splice site selection in vivo via a purine rich enhancer . ^^^ |
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