| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| CCR 3 functional responses are regulated by both CXCR 3 and its ligands CXCL 9 , CXCL 10 and CXCL 11 . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| CXCL 9 inhibits eosinophil responses by a CCR 3 and Rac 2 dependent mechanism . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| This study further elucidates the roles of selected chemokines ( IP 10 , MIG , and RANTES ) and their receptors ( CCR 3 , CCR 5 , and CXCR 3 ) in asthma . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| OBJECTIVES : To investigate tissue samples from patients with CD30+ CLPD for the expression of the chemokine receptors CXCR 3 , CCR 4 and CCR 3 and their ligands MIG , TARC and RANTES . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| This was confirmed by functional responses : only Th2s responded with an increase in [ Ca2+ ] 1 to the CCR 3 and CCR 4 agonists eotaxin and thymus and activation regulated chemokine ( TARC ) , whereas only Th0s and Th1s responded to low concentrations of the CXCR 3 agonists IFN gamma inducible protein 10 ( IP 10 ) and monokine induced by IFN gamma ( Mig ) . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| The ligands of CXC chemokine receptor 3 , 1 TAC , Mig , and IP 10 , are natural antagonists for CCR 3 . ^^^ CXCR 3 , the receptor for 1 TAC ( interferon inducible T cell alpha chemoattractant ) , Mig ( monokine induced by gamma interferon ) , and IP 10 ( interferon inducible protein 10 ) , is expressed preferentially on Th 1 cells , whereas CCR 3 , the receptor for eotaxin and several other CC chemokines , is characteristic of Th 2 cells . ^^^ While studying responses that are mediated by these two receptors , we found that the agonists for CXCR 3 act as antagonists for CCR 3 . 1 TAC , Mig , and IP 10 compete for the binding of eotaxin to CCR 3 bearing cells and inhibit migration and Ca ( 2+ ) changes induced in such cells by stimulation with eotaxin , eotaxin 2 , MCP 2 ( monocyte chemottractant protein 2 ) , MCP 3 , MCP 4 , and RANTES ( regulated on activation normal T cell expressed and secreted ) . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| Finally , CCR 3 expression by CD4+ / CD45RO+ T cells was positively correlated with plasma levels of its ligand , eotaxin , whereas strong negative correlations were evident between CXCR 3 expression and IP 10 or Mig . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| Immunohistochemical staining was performed using antibodies for CXCR 3 ( a specific receptor for IP 10 and MIG ) , which is characteristic of Th 1 helper phenotype and CCR 3 , CCR 4 and ST 2 , which are features of Th 2 cells . ^^^ IP 10 , MIG and TARC positive HD cases contained higher numbers of Th 2 lymphocytes ( ST 2 CCR 3 or CCR 4 positive lymphocytes ) , compared to IP 10 , MIG and TARC negative HD cases ( p < 0 . 05 or < 0 . 5 ) . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| From the gene expression profiling , CCR 4 , CCR 3 , MIG , CXCR 3 and BLC were selected for immunohistochemistry . ^^^ ALCL ( n=26 ) expressed CCR 3 , NKL ( n=20 ) expressed MIG , and AILD ( n=29 ) expressed CXCR 3 and / or BLC . ^^^ |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07325 and P51677 |
Pubmed |
SVM Score :0.0 |
| NA |
|