Interacting proteins: Q07011 and Q13114 |
Pubmed |
SVM Score :0.78426456 |
While 4 1BB bound TRAF 2 and TRAF 1 , Ox 40 interacted with TRAF 3 and TRAF 2 . 0.78426456^^^ |
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Interacting proteins: Q07011 and Q13114 |
Pubmed |
SVM Score :0.0 |
We found that tumor necrosis factor receptor associated factor ( TRAF ) 1 , TRAF 2 , and TRAF 3 , all interacted with the cytoplasmic domain of 4 1BB . ^^^ Mutation analysis showed that TRAF 1 , TRAF 2 , and TRAF 3 were associated with one of two runs of acidic residues found in the cytoplasmic domain of 4 1BB . ^^^ |
|
Interacting proteins: Q07011 and Q13114 |
Pubmed |
SVM Score :0.0 |
We also observed that 12 TNFR family members ( p75TNFR , LTbetaR , RANK , HVEM , CD 40 , CD 30 , CD 27 , 4 1BB , GITR , BCMA , OX 40 , and TACI ) are each capable of activating the alternative NF kappaB pathway and conclude that TRAF 3 serves as a negative regulator of this pathway for all tested receptors . . ^^^ |
|
Interacting proteins: Q07011 and Q13114 |
Pubmed |
SVM Score :0.0 |
NA |
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