| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| The results presented here suggest that costimulatory receptors on CTL such as CD 27 , CD 134 ( 4 1BB ) , and MHC class 2 are capable of directly interacting with the corresponding ligands on T helper lymphocytes resulting in enhanced proliferation and survival of the CTL during the effector phase of antitumor immune responses . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| Expression and costimulatory effects of the TNF receptor superfamily members CD 134 ( OX 40 ) and CD 137 ( 4 1BB ) , and their role in the generation of anti tumor immune responses . ^^^ This study addresses the relative importance of CD 134 ( OX 40 ) and CD 137 ( 4 1BB ) in the costimulation of CD4+ and CD8+ T cells under comparable conditions of antigenic stimulation . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| However , growing evidence over the past few years has now shown that several members of the TNFR family , OX 40 ( CD 134 ) , 4 1BB ( CD 137 ) , and CD 27 , are equally important to the effective generation of many types of T cell response . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| This review focuses on CD 27 , 4 1BB ( CD 137 ) , OX 40 ( CD 134 ) , HVEM , CD 30 , and GITR , all of which can have costimulatory effects on T cells . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| To date , molecular targets chosen for Ab activation to generate antitumor effector cells have been confined on T cells , such as TCR / CD3 , CD 28 , CD 137 ( 4 1BB ) , CD 134 ( OX 40 ) , and inducible costimulator . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| The expanded CD8+ population contained more cells expressing CD 137 ( 4 1BB ) , CD 137 ( 4 1BBL ) , CD 30 ( Ki 1 ) , CD 40 and CD 134 ( OX 40 ) . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| The tumour necrosis factor ( TNF ) ligands CD 154 , CD 70 and TNF receptors CD 134 and CD 137 are all involved in allograft rejection . ^^^ The calcineurin inhibitors ( CI ) CsA and TAC strongly suppressed the induction of CD 70 , CD 137 and CD 154 , but not of CD 134 , upon pharmacological stimulation of T cells in vitro . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| Activation of resting human primary T cells with chimeric receptors : costimulation from CD 28 , inducible costimulator , CD 134 , and CD 137 in series with signals from the TCR zeta chain . ^^^ Human CD 33 specific chimeric receptors were generated with CD 28 , inducible costimulator , CD 134 , or CD 137 signaling regions in series with TCRzeta signaling region and transfected by electroporation into resting human primary T cells . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| CD4+ T cell populations in the peripheral blood were analysed for the expression of co stimulatory markers CD45RO , CD 70 , CD 80 , CD 86 , CD 137 , CD137L , CD 134 , CD 152 , CD 154 and ICOS . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| A panel of monoclonal antibodies specific for CD 27 ligand ( CD 70 ) , CD 30 ligand ( CD 153 ) , CD 134 ligand ( OX40L ) , and CD 137 ligand ( 4 1BBL ) were screened in vivo for their ability to affect the control of Mycobacterium avium infection in C57Bl / 6 mice . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| Assessment expression of the adhesion molecules , CD 134 and CD 137 , in patients with colorectal cancer by flow cytometry . ^^^ The aim of the study was to assess the expression of adhesion molecules , CD 134 and CD 137 , in the peripheral blood in correlation with clinical advancement , the histological grade , the size and type of tumour growth , tissue infiltration , and lymph node and metastases to lymph nodes and liver . ^^^ The expression of CD 134 was markedly higher , compared to CD 137 , both on the day of the surgery and ten days after the operation . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| CD 134 ( OX 40 ) and CD 137 ( 4 1 BB ) are glycoprotein molecules provides the potent costimulatory signal for T cells activation and proliferation ( to Th 1 and Th 2 subpopulation ) via interactions with their ligands CD134L / CD137L molecule , present on the surface of Ag presenting cells ( APC ) . ^^^ The analysis of CD3+ T lymphocytes co expressing CD 134 and CD 137 antigens on peripheral blood revealed an increased percentages of OX 40 / CD137 positive cells in patients with Graves ' disease ( p < 0 . 025 ) compared to the controls , while CD134L ( OX 40L ) molecules were detected in some hyperthyroid patients on activated monocytes . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| When stimulated with beryllium / APC , the adhesion molecule ICAM 1 was up regulated , as well as several costimulation molecules including CD 28 , OX 40 ( CD 134 ) , 4 1 BB ( CD 137 ) and B 7 1 ( CD 80 ) . ^^^ |
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| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q07011 and P43489 |
Pubmed |
SVM Score :0.0 |
| NA |
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