| FAK mediated src phosphorylation of endophilin A 2 inhibits endocytosis of MT 1 MMP and promotes ECM degradation . ^^^ Further , we identified an interaction between FAK ' s second Pro rich motif and endophilin A 2 ' s SH 3 domain . ^^^ Together , these results suggest a regulatory mechanism of cell invasion whereby FAK promotes cell surface presentation of MT 1 MMP by inhibiting endophilin A 2 dependent endocytosis . . ^^^ |