| Interacting proteins: P43146 and Q05397 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: P43146 and Q05397 |
Pubmed |
SVM Score :0.61280084 |
| Here we show that different regions of the intracellular domain of DCC directly interacted with the tyrosine kinases Src and focal adhesion kinase ( FAK ) . 0.61280084^^^ |
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| Interacting proteins: P43146 and Q05397 |
Pubmed |
SVM Score :0.0 |
| Here we report that the netrin receptor DCC ( deleted in colorectal cancer ) interacts with the focal adhesion kinase ( FAK ) , a kinase implicated in regulating cell adhesion and migration . ^^^ FAK was expressed in developing brains and was localized with DCC in cultured neurons . ^^^ Netrin 1 induced FAK and DCC tyrosine phosphorylation . ^^^ Taken together , these results indicate a new signaling mechanism for DCC , in which FAK is activated upon netrin 1 stimulation and mediates netrin 1 function ; they also identify a critical role for FAK in axon navigation . . ^^^ |
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