| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| To evaluate AS , the kidney were treated with a polyethyleneimine ( PEI ) staining method and the deposits in the lamina rara externa ( LRE ) of the GBM were counted on the electron micrographs . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| Genetic variations in TGF alpha s , RAR alpha s , NADH dehydrogenase , an enzyme involved in oxidative metabolism , and cytochrome P 450 , a detoxifying enzyme , have been implicated as contributing genetic factors . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| A significantly negative correlation ( P < 0 . 001 ) existed between U AE and the number of anionic sites ( AS ) in the lamina rara externa of glomerular basement membranes , as visualized by electron microscopy . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| Genetic variations in TGF alpha s , RAR alpha s , NADH dehydrogenase , an enzyme involved in oxidative metabolism , and cytochrome P 450 , a detoxifying enzyme , have been implicated as contributing genetic factors . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| There is no significant colocalisation observed between the staining of PML / PML RARA and PIC 1 in an APL derived cell line NB 4 , as compared to cells expressing only wild type PML . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| Examination by electron microscope revealed that the number of anionic sites ( AS ) in the lamina rara externa per 1000 nm of glomerular basement membrane ( GBM ) was significantly decreased in diabetic rats compared to control values ( 17 . 6 + or 0 . 4 vs . 21 . 9 + or 0 . 4 , P < 0 . 01 ) , whereas , significant recovery ( 20 . 3 + or 0 . 7 , P < 0 . 05 ) was observed after 4 weeks of epalrestat treatment . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| Examination by electron microscope revealed that the number of anionic sites ( AS ) in the lamina rara externa per 1000 nm of glomerular basement membrane ( GBM ) was significantly decreased ( 22 . 9+ / 0 . 2 to 16 . 1+ / 0 . 3 , p < 0 . 001 ) , after induction of diabetes , whereas , significant recovery ( 18 . 2+ / 0 . 1 , p < 0 . 001 ) could be obtained even by the smaller dose ( 25 mg / kg ) of captopril which did not exert either antihypertensive or antidiabetic effect on diabetic SHRs . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| METHODS : Urinary albumin excretion rate ( UAE ) , pore size of the lamina densa of the GBM visualized directly by the tissue negative staining method , and number of anionic sites ( AS ) in the corresponding portion of the lamina rara externa were determined for 6 weeks in diabetic rats without and with insulin treatment . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| Missense mutations in the PML / RARalpha ligand binding domain in ATRA resistant As ( 2 ) O ( 3 ) sensitive relapsed acute promyelocytic leukemia . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| CONCLUSION : Our data provide a rationale for combined ATRA and As therapies in ATL patients refractory to conventional therapy and expressing RARalpha in their leukemic cells . . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| The expression pattern of endogenous RA receptor alpha ( RARalpha ) and the ability of an RARalpha ( 1 ) specific antisense oligonucleotide ( AS ) to modulate otic capsule chondrogenesis are demonstrated in the inner ear and in culture . ^^^ In addition , a reduction in endogenous TGFbeta ( 1 ) and a marked suppression of chondrogenesis occur in RARalpha ( 1 ) AS treated cultures in comparison to untreated or oligonucleotide treated control cultures . ^^^ This chondrogenic suppression can be partially overcome by supplementation of RARalpha ( 1 ) AS treated cultures with exogenous TGFbeta ( 1 ) protein . ^^^ |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P10276 |
Pubmed |
SVM Score :0.0 |
| NA |
|