| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.75457487 |
| A significant positive correlation was found between potential GR and % AS ( r = 0 . 479 , Trial 1 ) , indicating that families with higher potential GR under normal conditions are more likely to suffer from AS under cold stress , compared to families with lower GR . 0.75457487^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| Histologically , the tumours were classified as granulation tissue like ( GR , n = 10 ) , angioma like ( A , n = 11 ) , angiosarcoma like ( AS , n = 9 ) and as spindle cell type ( SP , n = 5 ) . ^^^ When the GR type was grouped together with the A type , and the AS type with the SP type , statistically significant differences emerged for CD45+ and MT1+ tumour associated cells , and for survival time , respectively . ^^^ In all these instances , the GR / A group values were higher than those of the AS / SP group . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| Bovine pancreatic ribonuclease ( RNase ) A and S protein ( enzymatically inactive proteolytic fragment of RNase A which contains RNA binding site ) stimulate the activation , as evidenced by increasing DNA cellulose binding , of highly purified rat hepatic glucocorticoid receptor complexes . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| AS 232 266 react with both the denatured and the free native murine hsp 84 , but not with the bound hsp 84 present in the untransformed glucocorticoid receptor complexes ( GR ) . ^^^ Both AS 232 266 and peptide 232 266 were shown to decrease [ 3H ] dexamethasone binding by GR . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| Antigens are visualized by the staining product of the substrate naphthol AS GR phosphate and variamine blue salt . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| PURPOSE : To evaluate the catalytic activity of the red cell enzyme , glutathione reductase ( GR ) in pregnant women with Hb AS and with Hb AA , and in a group of non pregnant women with Hb AA , as well as the relationship of GR deficiency with Hb S . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| GR , GPx , and GST are not sensitive to As ( 5 ) ( IC ( 50 ) > 50 mM ) , and none of the enzymes are inhibited or activated by physiologically relevant concentrations of As ( 3 ) , As ( 3 ) ( GS ) ( 3 ) , or CH ( 3 ) As ( 3 ) , although CH ( 3 ) As ( 3 ) is the most potent inhibitor ( 0 . 3 mM < IC ( 50 ) < 1 . 5 mM ) . ^^^ Our results do not implicate a direct interaction of As with the glutathione related enzymes , GR , GPx , and GST , in the mechanism of arsenic toxicity . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| AH , DV , EH , HR , and YV are of positive correlation , AM , IC , NG , NL , and PS are of negative correlation . ( 2 ) GE , RE , GS , and KS are higher pH alpha amylase characteristic dipeptides ; AS , GS , DY , and GI are high pH alpha amylase characteristic dipeptides ; TE , VR , DS , and ET are middle pH alpha amylase characteristic dipeptides ; DK , NT , PT , and RV are low pH alpha amylase characteristic dipeptides ; AT , DS , GR , and SR are lower pH alpha amylase characteristic dipeptides . . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| The study was based on clinical examination , periodontal parameters recorded by one examiner ( AS ) and included measurement of pocket depth ( PD 1 ) followed by measurement of recession from the CEJ to gingival margin ( GR 2 ) . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| We used this multi tag system in an attempt to improve expression levels of two prokaryotic proteins elongation factor Tu ( TufB ) and DNA gyrase subunit A ( GyrA ) as well as two eukaryotic nuclear receptors glucocorticoid receptor ( GR ) and small heterodimer partner ( SHP ) . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| We report here that 0 . 05 1 microM ( 6 120 ppb ) As showed stimulatory effects on glucocorticoid receptor ( GR ) mediated gene activation in rat EDR 3 hepatoma cells of both the endogenous tyrosine aminotransferase ( TAT ) gene and the reporter genes containing TAT glucocorticoid response elements . ^^^ Interestingly , the inhibitory effect of GR on both AP 1 and NF kappa B mediated gene activation was not affected by As . ^^^ The magnitude of GR stimulation and inhibition by As was highly dependent on the cellular level of hormone activated GR . ^^^ Mutational deletion studies indicated that the central DNA binding domain ( DBD ) of GR is the minimal region required for the As effect and does not require free sulfhydryls . ^^^ Point mutations located within the DBD that have known structural consequences significantly altered the GR response to As . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| To elucidate the mechanisms underlying this phenomenon , we evaluated whether the glucocorticoid receptor ( GR ) beta expression of the peripheral blood mononuclear cells ( PBMCs ) in patients with AS is increased compared with patients with RA . ^^^ GR beta mRNA expression of the AS patients ( 2 . 02 [ range : 0 . 99 7 . 21 ] , median [ 25th 75th percentiles ] ) was enhanced compared with that of the controls ( 0 . 78 [ range : 0 . 43 1 . 62 ] ) and the RA patients ( 0 . 98 [ range : 0 . 79 1 . 18 ] ) . ^^^ The level of GR beta mRNA expression was not related to the inflammatory markers or the disease activity score 28 for the RA patients , and it was not related to the Bath ankylosing spondylitis disease activity index for the AS patients . ^^^ CONCLUSION : The expression of GR beta mRNA , which is a dominant negative regulator for the glucocorticoid response , was increased in AS patients . ^^^ The results suggest that the increased expression of GR beta mRNA may be related to the ineffectiveness of glucocorticoids for the treatment of AS . . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| The GR group displayed similar crossing in the open field test as the VEH group ( F ( 2 , 19 ) = 8 . 78 , p < 0 . 002 ) , but also the shortest cumulative time in defensive burying ( F ( 2 , 28 ) = 13 . 3 , p < 0 . 0001 ) and the shortest time in freezing ( F ( 2 , 24 ) = 6 . 39 , p < 0 . 006 ) . ^^^ |
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| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05086 and P04150 |
Pubmed |
SVM Score :0.0 |
| NA |
|