Pubmed abstracts for Protein-Protein Interaction search result :


Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In a prospective study , 2 groups of male AS patients were investigated , one with increased elevated erythrocytic sedimentation rate ( ESR ) ( group A , n = 7 ) and one with normal ESR ( group B , n = 8 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The deletion common to our patients as well as to the reported patients may be confined to a segment between D15S11 and D15S10 , if the 5 loci are ordered as cen D15S18 ( D15S9 D15S11 D15S10 ) D15S12 qt er . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Serum glucose , serum immunoreactive insulin and sedimentation rate ( ESR ) were measured in eighteen male patients with ankylosing spondylitis ( AS ) and seven male healthy controls . ^^^ Fourteen patients had active AS with ESR of 47 . 0 + / 27 . 7 mm ; they had increased insulin levels measured as area under curve ( AUC ) of a glucose tolerance test 107 . 4 + / 44 . 1 cm 2 vs controls 40 . 8 + / 12 . 6 cm 2 ( p less than 0 . 03 ) . ^^^ In 4 patients with clinically inactive AS and with ESR of 17 . 0 + / 4 . 0 mm the insulin levels as the AUC were 83 . 2 + / 38 . 0 cm 2 vs controls ( p = ns ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
A set of early diagnostic ( ED ) criteria comprising clinical data , ESR , radiological spinal signs , and the risk factor HLA B 27 was evaluated after 5 and 10 years in a follow up of 54 patients with an initial diagnosis of possible ankylosing spondylitis ( AS ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Disease activity was assessed clinically and erythrocyte sedimentation rate ( ESR ) , C reactive protein ( CRP ) , orosomucoid , alpha 1 antitrypsin ( alpha 1AT ) and alpha 2 macroglobulin ( alpha 2M ) were measured in 65 patients with ankylosing spondylitis ( AS ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Clinical activity and degree of disability were evaluated every one to 3 months ; on each visit , every patient had determinations of serum and urinary uric acid levels , serum and phosphorus , erythrocyte sedimentation rate ( ESR ) , serum protein electrophoresis , as well as 10 ray films of the vertebral spine and pelvis . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Similarly AS related barium ( ASBa ) , localized in lysosomal structures and ( R ) ER was identified and differentiated . ^^^ In this case , PO related platinum containing reaction products ( PODAB / Pt or PODAB / Os ) in NE and RER has been identified and differentiated from the AcP ase related lysosomal cerium ( AcP aseCe ) and the AS related barium localized in lysosomal and ( R ) ER structures . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Ammonium sulfate ( AS ) precipitation by consecutive steps at 10 % to 50 % saturation has been utilized for fractionation of cytoplasmic estrogen receptor ( ER ) and progesterone receptor ( PgR ) . ^^^ ER and PgR salted out in the AS pellet are much more stable for storage than in the cytosol . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Such findings were associated with raised ESR and presence of peripheral arthritis in AS and with the duration of disease in PSA . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Forty four patients , 22 with ankylosing spondylitis ( AS ) and 22 with Reiter ' s syndrome ( RS ) were studied to determine the reliability of C reactive protein ( CRP ) levels and erythrocyte sedimentation rate ( ESR ) as indicators of disease activity . ^^^ CRP levels were significantly elevated in patients with active disease for both AS and RS while ESR values for active and inactive disease were not statistically different . ^^^ Misdiagnosis was more likely when ESR rather than CRP was used as the variable for activity . ^^^ CRP as measured by nephelometry is a more sensitive and specific indicator of disease activity in AS and RS than ESR . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Early diagnostic criteria , a combination of the HLA B 27 test with clinical data , ESR and radiological signs , were evaluated in a 5 6 year follow up study of 77 patients with possible ankylosing spondylitis ( AS ) and 45 with other rheumatic diseases . 34 ( 44 % ) with possible AS at first examination developed definite AS according to the New York criteria and 29 ( 38 % ) were classified as still possible AS . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Ia . 22 can be generated by the complementation of Ab , Ak , As , Ar , with Ed , Ek , Ep , Er , Ew 3 , Eu , Ev but Eb , Ef , Eq , and Es . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
When the non pregnant period was evaluated , elevated levels of IgG and IgM in RA and elevated ESR and IgA appeared to be predictive indices of the gestational remissions of RA and AS . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The mean IgA antibody to Klebsiella in AS patients with an erythrocyte sedimentation rate ( ESR ) greater than or equal to 15 mm / h was significantly higher than the antibody level in patients with an ESR less than 15 mm / h ( p less than 0 . 02 ) and tended to increase with rising ESR . ^^^ There was a significant difference in anti Klebsiella antibody levels between AS patients with an elevated ESR and antibody levels in PsA patients ( p less than 0 . 001 ) , RA patients ( p less than 0 . 001 ) and healthy controls ( p less than 0 . 005 ) . ^^^ There was no difference between healthy controls and patients with PsA , RA or AS patients with a low ESR . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Clinical laboratory data , namely , ESR ( erythrocyte sedimentation rate ) and CRP ( C reactive protein ) as an activity of rheumatic disease were evaluated . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Clinical studies indicate that faecal Klebsiella can be isolated more readily from AS patients during active phases of the disease , when this is defined either clinically , with or without uveitis , or biochemically by elevation in ESR and C reactive protein levels . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Patients with G AS were more often febrile ( rectal temperature greater than 38 degrees C ) and more often had a moderately elevated erythrocyte sedimentation rate ( ESR ) ( 16 to 30 mm / hr ) compared to other patients . ^^^ Women with NCNG AS were more likely to have a normal ESR and a mild inflammatory reaction laparoscopically . ^^^ C AS women were more likely to have had pelvic pain for more than 3 days before seeking treatment and to have an ESR of greater than 30 mm / hr on admission . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Total serum IgA in AS patients correlated with both erythrocyte sedimentation rate ( ESR ) ( P less than 0 . 001 ) and C reactive protein ( P less than 0 . 05 ) and was significantly elevated compared to healthy individuals ( P less than 0 . 001 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Peripheral blood `` total ' ' and `` avid ' ' T cell rosettes ( ER ) were enumerated in 35 patients with ankylosing spondylitis ( AS ) . ^^^ The in vitro effect of thymosin fraction 5 on `` avid ' ' ER formation was also determined . `` Total ' ' ER numbers , but not proportions , were lower in patients with AS as compared to matched controls , Both the proportion and number of `` avid ' ' ER were lower in the patient group . ^^^ It is suggested that there are increased numbers of circulating T lymphocytes in patients with AS that can respond to exogenous thymic factors and acquire the capability to form `` avid ' ' ER . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In the AS group there was a positive correlation between urinary excretion of PYR and inflammatory disease activity ( erythrocyte sedimentation rate ( ESR ) ) ( r = 0 . 6 , p < 0 . 0001 ) and C reactive protein ( CRP ) ( r = 0 . 3 , p = 0 . 02 ) , but no significant correlation was found with ESR , CRP , and markers of bone formation . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
ER were localized with both anti ER monoclonal antibody and polyclonal antibody ( AS 409 ) and 1 nm immunogold followed by silver enhancement . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In AS , IL 6 correlated with clinical parameters of disease activity with significant correlation being observed with laboratory parameters of inflammation such as ESR , CRP , platelet count and clinical parameters of severity such as vertebral mobility . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The clinical and laboratory assessments such as pain and stiffness on a 10 cm visual analogue scale , knee circumference ( cm ) , 50 ft walking time ( s ) , CRP and ESR were measured before receiving the steroid injection and at 3 , 6 , 12 and 24 weeks . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The uptake and excretion rates of 23 elements , Be , Mn , Co , Zn , As , Rb , Sr , Y , Zr , Ce , Pm , Eu , Gd , Tb , Er , Tm , Yb , Lu , Hf , W , Re , Ir and Pt , were simultaneously determined under strictly identical experimental conditions . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Laboratory variables of inflammatory activity such as ESR , CRP , platelet count , and hemoglobin ( and anti DNA antibodies and complement levels in SLE ) were measured at the same time . ^^^ ESR , CRP , and platelets correlated inversely with CK values in RA , AS , and MI . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Using the spin label method ( ESR ) it has been shown that biologically active , amphiphilic compounds ( quaternary ammonium salts ( AS ) containing polar heads with single and double positive charge caused , at low concentrations , decrease fluidity of liposome membranes formed with egg yolk lecithin ( EYL ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
As part of a larger effort to understand RNase 3 and Era structure and function , we characterized rnc operon structure , function and regulation in the closely related bacterium Salmonella typhimurium . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The percentage of administered dose of the 17 elements , Mn , Co , Zn , As , Rb , Sr , Y , Eu , Gd , Er , Tm , Yb , Lu , W , Re , Ir and Pt in the organs blood and excreta were determined using gamma ray spectrometry . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
METHODS : We measured estrogen receptor expression ( as % of positive cells ) by immunohistochemistry in normal breast epithelium from 376 women undergoing diagnostic or therapeutic breast surgery . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Clinical assessments included the BASDAI ( Bath AS Disease Activity Index ) , BASFI ( Functional Index ) , and BASMI ( Metrology Index ) , and laboratory assessments hemoglobin and erythrocyte sedimentation rate ( ESR ) at baseline and one month after final 60 mg dose of pamidronate . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The E 2 like effects of non steroidal antiestrogens in this model system can not be explained by the mutation in the ER alone because 4 OHT acts as an agonist with wildtype receptor as well . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Among the raw materials used are silica sand , borax , carbonates , nitrates of Ca , Na , K , and a great number of compounds that are mainly oxides of As , Sb , Al , Zn , Cr , Ni , Sn , Se , Cd , Mn , Cu , Co , Fe , Nd , Er , Eu , and La . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The objective of this clinically oriented literature review was to examine and compare the validity of erythrocyte sedimentation rate ( ESR ) and C reactive protein ( CRP ) in ankylosing spondylitis ( AS ) clinical trials . ^^^ AS studies were identified and selected if they included ESR and / or CRP and either presented data about their relation with disease activity or were designed as longitudinal clinical trials . ^^^ The selected studies were examined for truth ( association with disease activity ) , discriminative power ( sensitivity to change and discrimination between active and inactive treatment in longitudinal clinical trials ) , and feasibility ( e . g . , applicability and costs ) of ESR and CRP in AS . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Our aim was to determine whether C reactive protein ( CRP ) or erythrocyte sedimentation rate ( ESR ) is more appropriate in measuring disease activity in ankylosing spondylitis ( AS ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
OBJECTIVE : In this study , we aimed to determine the urinary levels of pyridinium cross links and urinary beta isomerized fragments derived from the C telopeptide of the alpha 1 chain of type 1 collagen ( beta CTX ) as markers of bone resorption in patients with ankylosing spondylitis ( AS ) , and to study their relationship to markers of disease activity [ erythrocyte sedimentation rate ( ESR ) ] and to disease subsets of this condition . ^^^ In the different disease subsets of AS , we found that patients with peripheral involvement had higher ( f Pyr + f Dpyr ) ( P = 0 . 04 ) and f Dpyr levels ( P = 0 . 04 ) , patients with early disease had elevated ( f Pyr + f Dpyr ) ( P = 0 . 01 ) , f Dpyr ( P = 0 . 02 ) and f Pyr ( P = 0 . 01 ) levels , and that those with raised ESR had enhanced f Dpyr ( P = 0 . 009 ) excretion . ^^^ However , urinary excretion of some of these collagen compounds was enhanced in subgroups of AS , mainly in patients with raised ESR . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
However , there were no demonstrable correlations between the quantitative expression of B 27 and clinical features such as age , disease duration , results of the Schober test , chest expansion , the WBC count , erythrocyte sedimentation rate ( ESR ) and C reactive protein ( CRP ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
OBJECTIVE : To investigate whether plasma levels of matrix metalloproteinases 3 ( MMP 3 , stromelysin ) , MMP 1 ( collagenase ) , tissue inhibitor of metalloproteinases 1 ( TIMP 1 ) , and MMP1 / TIMP 1 complex ( MT complex ) are specifically elevated in erosive joint diseases compared to nonerosive rheumatic diseases , and to assess how these markers reflect the clinical activity of rheumatoid arthritis ( RA ) compared to circulating cytokines and markers of connective tissue turnover as well as established variables [ C reactive protein ( CRP ) , erythrocyte sedimentation rate ( ESR ) , and rheumatoid factor titer ] . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
METHODS : 24 patients with classic AS were examined to determine their clinical status ; complete blood count , erythrocyte sedimentation rate ( ESR ) , and C reactive protein ( CRP ) were determined , and levels of the superoxide anion radicals in the patients with AS and 21 healthy subjects were assessed by the ultraweak chemiluminescence method . ^^^ RESULTS : In clinical assessments , patients with AS had abnormally raised serum CRP ( > 10 mg / l ) and ESR ( > 15 mm / 1st h ) levels . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The AS group was classified according to duration of disease , erythrocyte sedimentation rate ( ESR ) values and gender . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In 72 patients with AS , the two valuable surrogate markers of disease activity , erythrocyte sedimentation rate ( ESR ) and C reactive protein ( CRP ) , and an established clinical activity score ( Bath Ankylosing Spondylitis Disease Activity Index , BASDAI ) were correlated to the serum levels of SAA . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The clinical parameters arthritis score ( AS ) , hind paw volume ( HPV ) , body weight , and erythrocyte sedimentation rate ( ESR ) were determined . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In patients with established ankylosing spondylitis ( AS ) and a healthy control group , plasma levels of IGF 1 and TNF alpha as well as possible connections with biochemical markers of the bone metabolism , humoral inflammatory activity ( ESR , CRP ) , clinical manifestations , and an established clinical activity score ( Bath Ankylosing Spondylitis Activity Index = BASDAI ) were examined . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
To determine whether the turnover of the native enzyme similarly recruited this pathway , we heterologously expressed this protein in wild type Saccharomyces cerevisiae and mutant strains ( hrd1Delta , hrd 2 1 , and hrd3Delta ) previously shown to be deficient in the Ub dependent 26S proteasomal degradation of the polytopic ER protein 3 hydroxy 3 methylglutaryl CoA reductase ( isoform Hmg2p ) , the rate limiting enzyme in sterol biosynthesis , as well as in strains deficient in ER associated Ub conjugating enzymes , Ubc6p and / or Ubc7p ( Hampton et al . ( 1996 ) Mol . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Persistent systemic inflammation was defined as mean ESR > or = 28 mm / h or mean CRP > or = 15 mg / l . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Sigma ( 1 ) receptors are unique endoplasmic reticular ( ER ) proteins that bind ( + ) benzomorphans , neurosteroids and psychotropic drugs such as cocaine . ^^^ Cocaine , via sigma ( 1 ) receptors , can cause the dissociation of a cytoskeletal adaptor protein ankyrin from inositol ( 1 , 4 , 5 ) trisphosphate [ Ins ( 1 , 4 , 5 ) P ( 3 ) ] receptors on the ER as a sigma ( 1 ) receptor ankyrin complex , which then translocates to the plasma membrane and nucleus . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The human genes for C / EBP homology protein ( chop ) and asparagine synthetase ( AS ) are model systems to investigate transcription induced by nutrient limitation and endoplasmic reticulum ( ER ) stress . ^^^ Whereas chop expression is associated with cell stress and apoptosis , activation of the AS gene by ER stress indicates that asparagine may also be critical for cellular processes other than protein synthesis . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
We studied changes in the hardness , relaxation modulus [ Er ( t ) ] , and weight change ratio ( Wc ) of experimental photo activated acrylic soft lining materials ( EPLs ) stored in three aqueous solutions [ distilled water ( DW ) , physiological saline solution ( PS ) , and artificial saliva ( AS ) ] at 37 degrees C for 8 weeks . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Twenty six elements ( Li , 5 , Co , Ni , Cu , Zn , Ga , As , Rb , Sr , Ba , La , Ce , Pr , Nd , Sm , Eu , Gd , Tb , Dy , Ho , Er , Tm , Yb , Lu , and Pb ) were measured in common at the two labs in three different wine samples ( red and white Bordeaux table wines and Port wine ) and the results were compared . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The primary outcome measure was the BASDAI , and secondary outcomes included the Bath AS Functional Index ( BASFI ) , Bath AS Global Index ( BASGI ) , Bath AS Metrology Index ( BASMI ) , erythrocyte sedimentation rate ( ESR ) , C reactive protein ( CRP ) level , and percentage of patients achieving a reduction of > or = 25 % in the BASDAI . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Monoclonal antibody to TNFalpha in patients with AS demonstrated significant clinical response with significant reduction in the acute phase reactants ESR and CRP . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The atherosclerosis severity score ( AS ) of the abdominal aorta and carotid arteries were determined by sonography and the ESR 1 PvuII genotypes ( P / P , P / p and p / p ) by PCR . ^^^ RESULTS : HRT , time and ESR 1 PvuII genotype had a statistically significant or borderline significant main effect on AS during 5 year follow up ( P=0 . 004 , P < 0 . 001 and P=0 . 090 , respectively ) , when analyzed by repeated measures analysis of variance . ^^^ CONCLUSIONS : Our results suggest that the effect of HRT EVP in postmenopausal women on progression of AS may be determined in part by the genotype of ESR 1 PvuII . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Laboratory indices such as ESR , C 3 , IgA and CRP reduced obviously after treatment ( P < 0 . 01 or P < 0 . 05 ) , and better effect was shown in the treated group ( P < 0 . 05 ) . 10 ray film after treatment showed improvement in 11 cases in the treated group and 4 in the control group , inter group comparison showed significant difference ( chi 2 = 7 . 99 , P < 0 . 01 ) , the effect of HZJD was better than that of the control . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
THE IMPORTANCE OF SULFUR IN BIOLOGICAL SYSTEMS AS DETERMINED BY ESR STUDIES . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
COMPLEX FORMATION BETWEEN GLYCEROL AND METAL IONS AS STUDIED BY MEANS OF ESR , NMR , AND OPTICAL ABSORPTION SPECTROSCOPY . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
RESULTS : The AS patients show a highly significant positive correlation between Pyd and the inflammatory activity ( CrP , r = 0 . 36 , p < 0 . 001 : ESR , r = 0 . 379 , p < 0 . 001 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The multielement compositions ( Al , As , B , Ba , Be , Ca , Cd , Co , Cr , Cs , Cu , Fe , Ga , Hf , Li , Mn , Mo , Nb , Ni , Pb , Rb , Sb , Sc , Sr , Ti , Th , Tl , U , 5 , W , Y , Zn , Zr , La , Ce , Pr , Nd , Sm , Eu , Gd , Tb , Dy , Ho , Er , Tm , Yb , and Lu ) of soil , grape juices ( prepared in the laboratory ) , and samples collected in the different steps of each winemaking process were measured . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
METHODS : One hundred fifty three patients with ERA / RA , psoriatic arthritis ( PsA ) , early psoriatic arthritis ( EPsA ) ankylosing spondylitis ( AS ) , systemic lupus erythematosus ( SLE ) , juvenile idiopathic arthritis ( JIA ) , early undifferentiated seronegative arthritis ( UA ) , and osteoarthritis ( OA ) were investigated . ^^^ For example , agalactosylated structures were increased in ERA / RA and EPsA / PsA ( p = 0 . 0001 0 . 004 ) and digalactosylated structures were decreased in PsA , AS , and JIA ( p = 0 . 0001 0 . 04 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Outcome measures included the Bath AS Disease Activity Index ( BASDAI ) , Functional Index ( BASFI ) , Global Index ( BAS G ) , IgA , C reactive protein ( CRP ) , and eosinophil sedimentation rate ( ESR ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
CONCLUSION : The clinical characteristics of ERA can facilitate an early diagnosis so as to avoid joint damage and disabilities . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Significant positive correlations were found for 5 , Fe , Co , As , Y , Mo , Cd , Sb , Ce , Sm , Er , Tl and Pb in Hylocomium splendens , and for Mg , 5 , Fe , Co , As , Se , Y , Mo , Cd , Sb , Tl and Pb in Pleurozium schreberi . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
To assess validity , the patients were evaluated with the Bath AS Disease Activity Index ( BASDAI ) , Bath AS Metrology Index ( BASMI ) , Bath AS Patient Global Score ( BAS G ) , physicians ' assessment of disease activity , Bath AS Radiology Index spine ( BASRI s ) and sacroiliac joints , erythrocyte sedimentation rate ( ESR ) , and C reactive protein ( CRP ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
METHODS : Forty one patients with AS , divided into active and inactive groups according to their CRP and ESR , and 30 healthy volunteers were entered into the study . ^^^ BASDAI was positively correlated with VAS , ESR and CRP ; but MPO was negatively correlated with thiol / albumin ratio , both in total and active AS patients . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In a third control cohort the PMR AS correlated highly with patient ' s global assessment , patient satisfaction , and ESR ( p < 0 . 001 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
METHODS : In an open study , mesalazine ( 3 4 g / day ) was prescribed for 24 weeks to 20 patients ( aged 18 70 yrs ) with active AS , defined as the presence of at least one clinical criterion ( morning stiffness > 30 min , peripheral synovitis , enthesopathy , or pain score > 2 on a visual analog scale of 10 cm ) and one laboratory criterion [ erythrocyte sedimentation rate ( ESR ) > 20 mm / h or C reactive protein ( CRP ) > 20 mg / l ] . ^^^ CONCLUSION : No significant improvement in any disease activity variable of active AS was observed during treatment with Salofalk except for the ESR . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Encapsulation complexes formulated as { [ La ( DMF ) ( 9 ) ] ( 2 ) [ Cu ( 12 ) ( CN ) ( 18 ) ] . 2DMF } ( infinity ) , 1 , and { [ Ln ( DMF ) ( 8 ) ] [ Cu ( 6 ) ( CN ) ( 9 ) ] . 2DMF } ( infinity ) ( Ln = Eu , 2 ; Gd , 3 ; Er , 4 ) were obtained from the one step reaction of LnCl ( 3 ) ( Ln = La , Eu , Gd , Er ) with CuCN and KCN in DMF . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
AUTHORS ' CONCLUSIONS : Across all AS patients , SSZ demonstrated some benefit in reducing ESR and easing morning stiffness , but no evidence of benefit in physical function , pain , spinal mobility , enthesitis , patient and physician global assessment . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
In the era of more intense perioperative medical management of patients who undergo noncardiac surgery , the presence of AS increases the risk for perioperative AMI but not overall mortality . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The vitamin D status was investigated , as was , in parallel , the relationship to disease activity ( erythrocyte sedimentation rate [ ESR ] , C reactive protein [ CRP ] , Bath Ankylosing Spondylitis Disease Activity Index [ BASDAI ] ) , markers of bone metabolism ( parathyroid hormone [ PTH ] , 1 . 25 vitamin D 3 , 25 vitamin D 3 ) , calcium , bone alkaline phosphatase ( bone AP ) , urine cross links , and plasma tumor necrosis factor alpha ( TNFalpha ) . ^^^ AS patients with osteoporosis showed significantly increased CRP , ESR , cross links and PTH and a significantly decreased 1 . 25 D 3 . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
OBJECTIVE : To determine whether erythrocyte sedimentation rate ( ESR ) or C reactive protein ( CRP ) is more appropriate in measuring the disease activity in ankylosing spondylitis ( AS ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Clinical ( morning stiffness , nocturnal pain , Bath AS Disease Activity Index ) and laboratory [ erythrocyte sedimentation rate ( ESR ) , C reactive protein ( CRP ) ] assessments of disease activity were performed at baseline and at either 16 weeks ( clinical trial cohort ) or at 14 weeks ( observational cohort ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
For validity the functional indices were correlated with the Bath Ankylosing Spondylitis Disease Activity Index ( BASDAI ) , Bath Ankylosing Spondylitis Metrology Index ( BASMI ) , Bath Ankylosing Spondylitis Patient Global Score ( BAS G ) , modified Health Assesment Questionnaire ( HAQ S ) , SF 36 physical component summary ( SF 36 PCS ) , stiffness , pain , physician ' s assessment of disease activity , Bath AS Radiology Index total ( BASRI t ) , erythrocyte sedimentation rate ( ESR ) , and C reactive protein ( CRP ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
OBJECTIVE : To submit serum levels of matrix metalloproteinases ( MMPs ) and tissue inhibitors of metalloproteinases ( TIMPs ) to statistical analyses to test their exact degrees of clinical usefulness as biomarkers for detecting high disease activity in ankylosing spondylitis ( AS ) , comparing them with erythrocyte sedimentation rate ( ESR ) and C reactive protein ( CRP ) . ^^^ Most importantly , using receiver operating characteristic plots to analyse the two cohorts , MMP 3 was more accurate than ESR and CRP in detecting AS patients with high disease activity ( P = 0 . 01 and P = 0 . 009 , respectively ) . ^^^ CONCLUSION : Using several analytical approaches that have never been reported previously , we showed that MMP 3 is a more useful biomarker than ESR and CRP to detect high disease activity in AS . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
The impact of the N97D mutation in the exit from the endoplasmic reticulum ( ER ) was analysed by western blot after endoglycosidase H treatment , and it was found that B * 2704 N97D was retained and accumulated as unfolded molecules . ^^^ It has been suggested that AS may arise because of aberrant folding of HLA B 27 molecules within the ER . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
RESULTS : ER alpha and ER beta mRNA and protein were detected from as early as 16 dg . ^^^ As for ER beta , four bands ( 76 , 59 , 54 and 41 kDa ) were detected . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
CONCLUSION : Across all patients with AS , SSZ showed some benefit in reducing ESR and easing spinal stiffness , but no evidence of benefit in physical function , pain , spinal mobility , enthesitis , or patient and physician global assessment . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Postoperative bile leakage ( P = 0 . 001 ) , a female donor / male recipient combination ( P = 0 . 010 ) , and the era of transplantation ( P = 0 . 006 ) were independent risk factors for the development of an AS . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
A precise molecular explanation for the association between HLA B 27 and AS is still lacking , although it is known that inappropriately disulfide bonded HLA B 27 heavy chains can be found at both the cell surface and in the endoplasmic reticulum ( ER ) of HLA B 27 expressing cells . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
RESULTS : Improvement in sacroiliitis index , Schober test , occipital wall test , finger ground distance , as well as the erythrocyte sedimentation rate ( ESR ) and the content of C reactive protein ( CRP ) in Group B and C was far superior to that of Group A ( P < 0 . 01 ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
RESULTS : Patients with mitral valve prolapse compared with the group of the AS patients without this abnormality had significant higher ( p = 0 . 05 ) activity of the disease assessed by ESR . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Absence of ER and PR in these tumors in the presence of high levels of E 6 AP could contribute to steroid receptor independent function and tumorigenesis . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
Further , 4EM mediated transcription in ER alpha , like estrogen , was enhanced in the presence of coactivators , steroid receptor coactivator 1 ( SRC 1 ) , CREB binding proteins ( CBP ) , and E 6 associated protein ( E 6 AP ) . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
We demonstrated that the expression of E 6 AP protein is decreased in human invasive breast and prostate carcinomas compared with their adjacent normal tissues , and this down regulation of E 6 AP is accompanied by the up regulation of estrogen receptor ( ER ) alpha in breast and androgen receptor ( AR ) in prostate carcinomas . ^^^ Furthermore , our in vivo data from E 6 AP knockout animals indicated that the expression levels of ERalpha and AR are increased in E 6 AP null mammary and prostate glands , respectively , when compared with that of normal control animals , suggesting that E 6 AP modulates the protein levels of ERalpha in breast and AR in prostate glands . . ^^^
Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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Interacting proteins: Q05086 and P03372 Pubmed SVM Score :0.0
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