| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Here , we identify in a yeast two hybrid screen a PDZ protein termed SIP 1 , as an interacting protein with human SRY . ^^^ Interacting domains were mapped to the C terminal seven amino acids of SRY and to the PDZ domains of SIP 1 , respectively . ^^^ We hypothesize that SIP 1 could connect SRY to other transcription factors providing SRY for its missing trans regulation domain . . ^^^ |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Using the farwestern protein blotting technique and recombinant fusion proteins containing the Sry Q rich domain as probes , three Sry interactive proteins of 94 , 32 and 28 kDa apparent molecular weight ( Sip 1 , 2 and 3 respectively ) were consistently detected in adult testis . ^^^ |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Acute administration of TDF was also found to significantly increase dopamine ( DA ) and homovanillic acid ( HVA ) levels while the dihydroxyphenylacetic acid ( DOPAC ) level remained unchanged in both the nucleus accumbens ( NA ) and striatal ( ST ) tissues when compared to control . ^^^ On the other hand , in animals receiving repeated TDF administration , only the HVA level was significantly increased in both the ST and NA . ^^^ |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| Adaptative biochemical changes in dopaminergic function were examined after both acute ( 100 mg / kg ) and repeated administration of TDF ( 100 mg / kg , 14 days ) by examining [ 3H ] dopamine ( DA ) uptake and DA release in both striatal ( ST ) and nucleus accumbens ( NA ) tissue . ^^^ Repeated TDF exposure in vivo resulted in significant attenuation of ST and NA DA uptake in response to TDF ( 10 ( 4 ) to 10 ( 7 ) M ) or cocaine ( 10 ( 5 ) to 10 ( 8 ) M ) in vitro . ^^^ Repetitive administration of TDF in vivo had no effect on in vitro TDF or amphetamine stimulated release of ST or NA DA . ^^^ It was concluded from this study that the effects of chronic TDF exposure may primarily involve effects on DA uptake in the ST and NA . . ^^^ |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| RESULTS : Outcomes were analysed in 570 individuals according to treatment modality ( 98 drug naive versus 472 simplified ) ; the nucleoside analogue ( NA ) backbone ( 298 with TDF + ddI , 88 with ddI , 44 with TDF , and 140 with neither ddI nor TDF ) ; and the third agent used ( 378 with non nucleoside analogues versus 192 with NA ) . ^^^ Significant CD4+ T cell declines were seen in patients taking ddI + TDF with respect to all other NA combinations , including ddI or TDF separately . ^^^ |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q05066 and Q15599 |
Pubmed |
SVM Score :0.0 |
| NA |
|