Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
A procedure in which three sequential enzymes of cholesterol biosynthesis , mevalonate kinase ( ATP : ( R ) mevalonate 5 phosphotransferase , EC 2 . 7 . 1 . 36 ) , phosphomevalonate kinase ( ATP : ( R ) 5 phosphomevalonate phosphotransferase , EC 2 . 7 . 4 . 2 ) and mevalonate 5 diphosphate decarboxylase ( ATP : ( R ) 5 diphosphomevalonate carboxy lyase ( dehydrating ) , EC 4 . 1 . 1 . 33 ) , from pig liver , could be purified in the one operation is described . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
The immediate biosynthetic precursors of isopentenyl diphosphate ( hydroxymethylglutaryl CoA , mevalonate , mevalonate 5 phosphate , mevalonate 5 diphosphate ) , on the other hand , are not accepted as substrates and the corresponding enzymes hydroxymethylglutaryl CoA reductase , mevalonate kinase , phosphomevalonate kinase , and diphosphomevalonate decarboxylase are not present in the organelles . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
The activity of mevalonate kinase and of mevalonate pyrophosphate decarboxylase in human skin fibroblasts grown in culture was increased when whole fetal calf serum in the incubation medium was replaced with lipid deficient serum . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
The activated genes include mevalonate kinase , mevalonate pyrophosphate decarboxylase , isopentenyl phosphate isomerase , geranylgeranyl pyrophosphate synthase , farnesyl pyrophosphate synthase , squalene synthase , squalene epoxidase , lanosterol synthase , lanosterol demethylase , and 7 dehydro cholesterol reductase . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
These five enzymes all have been reported to be partly or exclusively peroxisomal and include HMG CoA reductase , mevalonate kinase , phosphomevalonate kinase , mevalonate pyrophosphate decarboxylase , and isopentenyl pyrophosphate isomerase . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
The addition of rIFN alpha to liquid cultures resulted in a dose dependent inhibition of normal marrow and MPD marrow MK growth . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
We studied the behavior in culture of megakaryocyte progenitor cells ( CFU Mk ) from peripheral blood ( PB ) and bone marrow ( BM ) cells in eight patients with myeloproliferative diseases ( MPD ) . ^^^ These data demonstrate an expansion of the CFU Mk pool in MPD patients without increased plasma levels of CSA Mk , and suggest that PB and BM CFU Mk of MPD patients might have different kinetic properties . . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
Megakaryocyte ( MK ) ploidy patterns were analysed by flow cytometry in 29 newly diagnosed and previously untreated patients with chronic myeloproliferative disorders ( MPD ) and concomitant thrombocytosis , in 9 patients with reactive thrombocytosis ( RT ) and in 12 healthy individuals . ^^^ |
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Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
|
Interacting proteins: Q03426 and P53602 |
Pubmed |
SVM Score :0.0 |
NA |
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