| Interacting proteins: Q03405 and P23458 |
Pubmed |
SVM Score :0.85154911 |
| Upon clustering of uPA . uPAR complex by a monoclonal antibody , JAK 1 associates with uPAR , which in turn leads to STAT 1 phosphorylation , dimerization , specific binding to DNA , and gene activation . 0.85154911^^^ |
|
| Interacting proteins: Q03405 and P23458 |
Pubmed |
SVM Score :0.0 |
| By using co immunoprecipitation techniques and in vitro kinase assays , the uPAR associated proteins were identified as Janus ( Jak ) and Src non receptor protein tyrosine kinases ( PTK ) Jak 1 , Tyk 2 , and p 59 ( fyn ) , p53 / 56 ( lyn ) , p53 / 59 ( hck ) , and p 55 ( fgr ) . ^^^ Migration experiments with double immunofluorescence staining revealed polarization of uPAR , and colocalization with Jak 1 and Tyk 2 to the leading edge of the migrating cells . ^^^ |
|
| Interacting proteins: Q03405 and P23458 |
Pubmed |
SVM Score :0.0 |
| NA |
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