| The tight association of Neu 3 with caveolin 1 was supported further by co immunoprecipitation of Neu 3 by anti caveolin 1 antibody . 0.72486707^^^ Using HeLa cells and Neu 3 transfected COS 1 cells , endogenous and exogenous Neu 3 was found to co concentrate caveolin 1 in low density Triton 10 100 insoluble membrane fractions on sucrose density gradients of the respective cell extracts , as assessed by enzyme activity assays and immunoblotting with a monoclonal antibody to human Neu 3 . 0.5298899^^^ |