| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| IGF 1 regulates caveolin 1 and IRS 1 interaction in caveolae . ^^^ Moreover , IRS 1 co immunoprecipitates with caveolin 1 and the specific phosphocaveolin 1 IRS 1 interaction is increased by IGF I . . ^^^ |
|
| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| Likewise , we determined that insulin dependent insulin receptor and IRS 1 tyrosine phosphorylation was not significantly different in the four cell lines representing parental , low , medium , and high levels of caveolin 1 expression . ^^^ |
|
| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| We now found that impairment of glimepiride induced lipolytic cleavage of GPI proteins in rat adipocytes by the novel inhibitor of glycosylphosphatidylinositol specific phospholipase C ( GPI PLC ) , GPI 2350 , caused almost complete blockade of ( 1 ) dissociation from caveolin 1 of pp 59 ( Lyn ) and GPI proteins , ( 2 ) their redistribution from high cholesterol ( hcDIGs ) to low cholesterol containing ( lcDIGs ) lipid rafts , ( 3 ) tyrosine phosphorylation of pp 59 ( Lyn ) and insulin receptor substrate 1 protein ( IRS 1 ) and ( 4 ) stimulation of glucose transport as well as ( 5 ) inhibition of isoproterenol induced lipolysis in response to glimepiride . ^^^ |
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| Interacting proteins: Q03135 and P35568 |
Pubmed |
SVM Score :0.0 |
| Insulin stimulated activation of insulin receptors and downstream molecules , such as IRS 1 and Akt , was attenuated in the skeletal muscles of Cav 3 null mice , but not in the liver , without affecting protein expression or subcellular localization . ^^^ |
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