| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| Caveolin 1 was not cofractionated with APP . ^^^ |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| Caveolin 1 , a principal component of caveolae , is physically associated with APP , and the cytoplasmic domain of APP directly participates in this binding . ^^^ |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| On the basis of our research , several processes seem to be important in relation to the still speculative pathogenesis : 1 ) increased transcription and accumulation of amyloid beta precursor protein ( AbetaPP ) , and accumulation of its proteolytic fragment Abeta ; 2 ) abnormal accumulation of cholesterol , caveolin 1 , and apolipoprotein E ; 3 ) oxidative stress ; 4 ) accumulations of intramuscle fiber multiprotein aggregates ; and 5 ) evidence that unfolded / misfolded proteins participate in s IBM pathogenesis . ^^^ |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| Thus , this study was performed to examine whether caveolin 1 can regulate amyloid precursor protein ( APP ) processing in neuronal cells and to identify the molecular mechanisms involved in this regulation . ^^^ Moreover , detergent insoluble glycolipid ( DIG ) fractions indicated that caveolin 1 was co localized with APP in caveolae like structures . ^^^ In DIG fractions , beta APP secretion was up regulated by caveolin 1 over expression , which was modulated via protein kinase C ( PKC ) in neuroblastoma cells . ^^^ From these results we conclude that caveolin 1 is selectively expressed in senescent neurons and that it induces the processing of APP by beta secretase via PKC downregulation . . ^^^ |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| To characterize the molecular mechanism by which the AP Cav peptide and Cav 1 mediate eNOS inhibition , we subdivided the Cav portion of AP Cav into three domains ( Cav A , B , and C ) , synthesized five overlapping peptides ( AP Cav A , AB , B , BC , and C ) , and tested their effects on eNOS dependent activities . ^^^ |
|
| Interacting proteins: Q03135 and P05067 |
Pubmed |
SVM Score :0.0 |
| Here , we report that FLOT 1 binds to BACE 1 ( beta site APP cleaving enzyme 1 ) and that overexpression of CAV 1 or FLOT 1 results in recruiting BACE 1 into lipid rafts and influence on beta secretase activity in cultured cells . ^^^ |
|