| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Thus , flotillin 1 represents a new integral membrane protein marker for the slightly larger caveolae related domains ( 50 200 nm ) that are observed in cell types that fail to express caveolin 1 . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Strikingly , recycling endosomes are enriched in the raft lipids sphingomyelin and cholesterol as well as in the raft associated proteins caveolin 1 and flotillin 1 . ^^^ |
|
| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Although the GPI anchored proteins were readily separated by one dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis ( SDS PAGE ) , these proteins were undetectable on two dimensional ( 2 D ) gels , even though these gels unambiguously revealed high enrichment of known hydrophobic proteins of detergent resistant membranes such as caveolin 1 and flotillin 1 ( identified by Western blotting and tandem mass spectrometry , respectively ) . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Interestingly , the caveolae specific membrane proteins , caveolin 1 and 2 , were up regulated in GPI deficient cells , in contrast to flotillin 1 and GM 1 , which were expressed at normal levels . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| By Western blotting the plasma membrane raft fractions obtained using either non detergent or detergent based methods contained significant amounts of STAT 1 and STAT 3 ( up to approximately 10 % of the total cytoplasmic amount ) as well as the integral raft proteins caveolin 1 and flotillin 1 , the IL 6 receptor signal transducing chain gp 130 , the interferon gamma receptor alpha chain ( IFN gammaRalpha ) , and the chaperone glucose regulated protein 58 ( GRP58 / ER 60 / ERp57 ) . ^^^ The data show pre association of STATs with plasma membrane rafts in flotation fractions , which also contained caveolin 1 and flotillin 1 , and suggest that Tyr phosphorylation may not in itself be sufficient to cause the departure of PY STATs from plasma membrane rafts . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Triton 10 100 extraction on ice and flotation gradient centrifugation demonstrated that rapsyn and AChR are recovered in low density fractions enriched in two rafts markers : caveolin 1 and flotillin 1 . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| CLR were enriched on the basis of their unique buoyant density and composition of cholesterol , caveolin 1 , and flotillin 1 but not clathrin . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| In mammalian cells , DRM associated integral membrane proteins such as caveolin 1 and flotillin 1 that form oligomers have been linked to the formation of DRM based invaginations called caveolae . ^^^ Thus , like caveolin 1 and flotillin 1 , a stomatin may also associate with non clathrin coated , DRM enriched vacuoles . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| The proteins fall in to five groups : structural molecules of the droplet like adipose differentiation related protein ; multiple enzymes involved in the synthesis , storage , utilization , and degradation of cholesterol esters and triglycerides ; multiple , different Rab GTPases known to be involved in regulating membrane traffic ; signaling molecules such as p50RhoGAP ; and a group of proteins that do not fit any classification but include proteins often found in caveolae / rafts such as caveolin 1 and 2 and flotillin 1 . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| The nitrated proteins were localized to the raft fraction obtained by centrifugation of the homogenate in a sucrose density gradient , which contained specific raft markers such as flotillin 1 and caveolin 1 . ^^^ Both alpha and beta tubulin were detected in the rat brain raft fraction as abundant proteins , which co immunoprecipitate with flotillin 1 and caveolin 1 . ^^^ Importantly , some protein protein interactions in rafts were disrupted in 3 NY containing proteins , e . g . caveolin 1 was dissociated from a complex with flotillin 1 and alpha tubulin . ^^^ The analysis of age dependencies did not show any significant change in protein nitration and expression of flotillin 1 and alpha tubulin , but a decrease in the brain caveolin 1 level for old ( 34 months ) versus young ( 6 months ) rats . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| We report on the presence of the lipid raft specific proteins caveolin 1 and flotillin 1 in sperm cells . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Detergent treated plasma membranes were studied using Superose 6 chromatography which demonstrated co elution of PDE3B with caveolae and lipid raft markers ( caveolin 1 , flotillin 1 and cholesterol ) at a Mw of > 4000 kDa . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| Here , we report that FLOT 1 binds to BACE 1 ( beta site APP cleaving enzyme 1 ) and that overexpression of CAV 1 or FLOT 1 results in recruiting BACE 1 into lipid rafts and influence on beta secretase activity in cultured cells . ^^^ Our results show that both CAV 1 and FLOT 1 may modulate beta secretase activity by interacting with BACE1 . . ^^^ |
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| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: O75955 and Q03135 |
Pubmed |
SVM Score :0.0 |
| NA |
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