| Interacting proteins: Q02962 and P45983 |
Pubmed |
SVM Score :0.55908067 |
| Pax 2 can form a complex with the JNK scaffolding protein JIP 1 , and this interaction is enhanced by activation of the JNK signaling module with the upstream kinase DLK . 0.55908067^^^ |
|
| Interacting proteins: Q02962 and P45983 |
Pubmed |
SVM Score :0.0 |
| JNK initiates a cytokine cascade that causes Pax 2 expression and closure of the optic fissure . ^^^ We demonstrate that JNK initiates a cytokine cascade of bone morphogenetic protein 4 ( BMP 4 ) and sonic hedgehog ( Shh ) that induces the expression of the paired like homeobox transcription factor Pax 2 and closure of the optic fissure . ^^^ |
|
| Interacting proteins: Q02962 and P45983 |
Pubmed |
SVM Score :0.0 |
| Groucho suppresses Pax 2 transactivation by inhibition of JNK mediated phosphorylation . ^^^ The activation domain of Pax 2 is phosphorylated by the c Jun N terminal kinase ( JNK ) to enhance Pax 2 dependent transcription . ^^^ Grg 4 is able to specifically inhibit phosphorylation of the Pax 2 activation domain , even in the presence of activated JNK . ^^^ |
|
| Interacting proteins: Q02962 and P45983 |
Pubmed |
SVM Score :0.0 |
| NA |
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