| Interacting proteins: Q16584 and Q02750 |
Pubmed |
SVM Score :0.0 |
| Most of the mitogenic protein kinases including Raf 1 , RafB , Mek 1 , Erk 2 , and Rsk 1 were significantly down regulated , whereas the stress signaling kinases , such as Mlk 3 , Mekkl , Sekl , Mkk 3 , and Mapkapk 2 were up regulated in expression during postnatal development . ^^^ |
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| Interacting proteins: Q16584 and Q02750 |
Pubmed |
SVM Score :0.0 |
| Immunoprecipitated MLK 3 catalyses the phosphorylation of MEK 1 in vitro , but this phosphorylation leads only to a marginal activation . ^^^ In support of these data , we also show that MEK 1 is highly phosphorylated in vivo on Ser 217 / 221 in MLK 3 transformed fibroblasts , whereas activating ERK phosphorylations are barely detectable . ^^^ |
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| Interacting proteins: Q16584 and Q02750 |
Pubmed |
SVM Score :0.0 |
| Here we report that MLK 3 can phosphorylate and activate MEK 1 directly in vitro and also can induce MEK phosphorylation on its activation sites in vivo in COS 7 cells . ^^^ |
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| Interacting proteins: Q16584 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
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