Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
Cotransfection with dominant negative MEK 1 inhibited activation of each RSK ; furthermore , the kinase activity of RSK 1 , RSK 2 , and RSK 3 was markedly increased by cotransfection with constitutively active MEK 1 . ^^^ Furthermore , MAPKs in RSK 3 immunoprecipitates were phosphorylated by purified MEK 1 ; however , RSK 3 kinase activity was unaffected . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
Bombesin induced a marked and persistent activation of the mitogen activated protein kinase kinase 1 ( MEK 1 ) , p 42 ( mapk ) and p 90 ( rsk ) in Swiss 3T3 cells by a pathway that was independent of p 74 ( raf 1 ) but dependent on the activity of protein kinase C . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
Raf 1 , Raf B , Mek 1 , Mek kinase , and p 90 ( rsk ) kinases were also shown to be activated independently in a distinct time dependent pattern through the two Tnf receptors . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
Mitogens induce the sequential activation of the kinases Raf 1 > Mek 1 > Erk 2 > Rsk via the G protein Ras . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NRG 1 activated p42 / p44 mitogen activated protein kinase ( MAPK ) [ extracellular signal regulated kinase ( ERK ) 2 / ERK1 ] and ribosomal S 6 kinase ( RSK ) 2 ( 90 kDa ribosomal S 6 kinase ) , both of which could be inhibited by the MAPK / ERK kinase 1 antagonist PD 098059 . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
RSK activity was reduced by PI 3 kinase inhibitor LY 294002 or MEK 1 inhibitor PD 98059 , suggesting that the ERK as well as the PI 3 kinase pathways are involved in regulation of RSK activity . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
FGF 2 , but not VEGF induces a large activation of MEK 1 , ERK1 / 2 and P 90 ( RSK ) during CEC proliferation . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
PD 098059 , a specific inhibitor of MEK 1 , prevented the dual phosphorylation of p42 / 44 ( MAPK ) and also the phosphorylation of p 90 ( RSK ) ( ribosomal subunit S 6 kinase ) , which mirrored the kinetics of p42 / 44 ( MAPK ) phosphorylation . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
Signaling distal to MEK 1 involved extracellular signal regulated kinase ( ERK ) because inhibition of MEK 1 suppressed the Ang 2 induced activation of ribosomal S 6 kinase ( RSK ) , a substrate of ERK . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
These cytological events are accompanied by activation of MPF and the p 39 ( Mos ) MEK 1 Xp42 ( Mpk 1 ) p 90 ( Rsk ) pathways . ^^^ Using U 0126 , a MEK 1 inhibitor , and p 39 ( Mos ) antisense morpholino and phosphorothioate oligonucleotides , we have investigated the role of the members of the p 39 ( Mos ) MEK 1 Xp42 ( Mpk 1 ) p 90 ( Rsk ) in spindle morphogenesis . ^^^ Moreover , we have observed that Raf 1 phosphorylation that occurs during meiosis resumption was dependent upon the activity of MEK 1 or Xp 42 ( Mpk 1 ) but not p 90 ( Rsk ) . ^^^ Our results indicate that activation of the p 39 ( Mos ) MEK 1 Xp42 ( Mpk 1 ) p 90 ( Rsk ) pathway is required for bipolar organization of the meiotic spindle at the cortex . . ^^^
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA
Interacting proteins: Q15349 and Q02750	Pubmed	SVM Score :0.0
NA