| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| The first MEK activator has an apparent M ( r ) of 40 , 000 50 , 000 , was immunologically distinct from A Raf , B Raf , c Raf 1 , c MEKK , c Mos , MEK 1 , and MEK 2 , and was rapidly activated by serum , platelet derived growth factor ( PDGF ) , insulin , thrombin , and phorbol ester . ^^^ |
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| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| Selective activation of MEK 1 but not MEK 2 by A Raf from epidermal growth factor stimulated Hela cells . ^^^ We observed that stimulation of Hela cells with epidermal growth factor resulted in a rapid and transient activation of A Raf , which is then capable of phosphorylating and activating MEK 1 . ^^^ Interestingly , A Raf does not activate MEK 2 , although c Raf can activate both MEK 1 and MEK 2 . ^^^ Our data demonstrated that A Raf is , indeed , a MEK 1 activator and may play a role in growth factor signaling . . ^^^ |
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| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| Raf and MEK could abrogate the cytokine dependence of murine FDC PI and human TF 1 cells ; however , the frequency of transformation was dependent on the particular oncogene examined , as more factor independent cells were isolated after infection with activated retroviruses encoding A Raf or Raf 1 than were with MEK 1 or B Raf . ^^^ |
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| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: P10398 and Q02750 |
Pubmed |
SVM Score :0.0 |
| NA |
|