| Interacting proteins: Q13753 and Q02388 |
Pubmed |
SVM Score :0.0 |
| Purification by gel filtration gave pure ebR 2 with lambda max , 558 nm , similar to that of light adapted bacterio opsin reconstituted with all trans retinal ( ebR 1 ) . ^^^ Spectrophotometric titration of ebR 2 as a function of pH showed that the purple to blue transition of bacteriorhodopsin at acidic pH was altered , and the apparent pKa of Schiff base deprotonation at alkaline pH was lowered by 2 . 4 units , relative to that of ebR 1 . ebR 2 showed no light dark adaptation , no proton pumping , and no intermediates characteristic of the bacteriorhodopsin photocycle . ^^^ |
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| Interacting proteins: Q13753 and Q02388 |
Pubmed |
SVM Score :0.0 |
| These include mutations in the type 7 collagen gene ( COL7A1 ) in the dystrophic ( severely scarring ) forms of EB ; mutations in the laminin 5 genes ( LAMA 3 , LAMB 3 and LAMC 2 ) in a lethal ( Herlitz ) variant of junctional EB ; aberrations in the type 17 collagen gene ( COL17A1 ) in non lethal forms of junctional EB ; mutations in the alpha 6 and beta 4 integrin genes in a distinct hemidesmosomal variant of EB with congenital pyloric atresia ; and mutations in the plectin gene ( PLEC 1 ) in a form of EB associated with late onset muscular dystrophy . ^^^ |
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| Interacting proteins: Q13753 and Q02388 |
Pubmed |
SVM Score :0.0 |
| Non sense mutations on both alleles of either the type 7 collagen gene ( COL7A1 ) or the genes encoding laminin 5 ( LAMA 3 , LAMB 3 , or LAMC 2 ) usually result in clinically severe forms of recessive dystrophic or junctional epidermolysis bullosa , respectively . ^^^ |
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| Interacting proteins: Q13753 and Q02388 |
Pubmed |
SVM Score :0.0 |
| NA |
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