| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.91343478 |
| Binding experiments with a series of truncated XPC proteins allowed the centrin 2 binding domain to be mapped to a presumed alpha helical region near the C terminus , and three amino acid substitutions in this domain abrogated interaction with centrin 2 . 0.91343478^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.77005614 |
| We demonstrate that nearly all XPC complexes contain CEN 2 , that CEN 2 interacts directly with XPC , and that CEN 2 , in cooperation with HR23B , stabilizes XPC , which stimulates XPC NER activity in vitro . 0.77005614^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.0 |
| Flexibility and plasticity of human centrin 2 binding to the xeroderma pigmentosum group C protein ( XPC ) from nuclear excision repair . ^^^ Human centrin 2 is a component of the nucleotide excision repair system , as a subunit of the heterotrimer including xeroderma pigmentosum group C protein ( XPC ) and hHR23B . ^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.0 |
| The interface between centrin 2 and each peptide is predominantly nonpolar , and key hydrophobic residues of XPC have been identified that lead us to propose a novel binding motif for centrin . . ^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.0 |
| CENTRIN 2 interacts with the Arabidopsis homolog of the human XPC protein ( AtRAD 4 ) and contributes to efficient synthesis dependent repair of bulky DNA lesions . ^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.0 |
| Crystallization and preliminary 10 ray diffraction data of the complex between human centrin 2 and a peptide from the protein XPC . ^^^ A complex formed by a Ca2+ bound human centrin 2 construct ( the wild type lacking the first 25 amino acids ) with a 17 mer peptide derived from the XPC sequence ( residues Asn 847 Arg863 ) was crystallized . ^^^ |
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| Interacting proteins: P41208 and Q01831 |
Pubmed |
SVM Score :0.0 |
| NA |
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