| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Both DP 1 and DP 2 synergistically interact with members of the E2F family of proteins , E2F 1 , E2F 2 , and E2F 3 , to generate DNA binding complexes that specifically recognize the E2F site and functionally interact with E2F 1 in E2F site dependent transcriptional activation of cellular genes . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Northern blot analysis of the expression of E2F and DP family members showed that the E2F 1 , E2F 4 , and E2F 5 mRNA was growth and senescence dependent , whereas E2F 3 , DP 1 , and DP 2 expression was constitutive and senescence independent . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Unlike E2F 1 , 2 , and 3 , E2F 4 did not accumulate in the nucleus unless it was coexpressed with DP 2 , p 107 and p 130 , but not pRb , stimulated nuclear localization of E2F 4 , either alone or in combination with DP 2 . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Five E2F genes , E2F 1 through E2F 5 , and two DP genes , DP 1 and DP 2 , have been isolated from mammals , and heterodimeric complexes of these proteins are expressed in most , if not all , vertebrate cells . ^^^ Using recombinant E2F , DP , and Rb proteins prepared in baculovirus infected cells and a repetitive immunoprecipitation PCR procedure ( CASTing ) , we have identified consensus DNA binding sites for E2F 1 / DP 1 , E2F 1 / DP 2 , E2F 4 / DP 1 , and E2F 4 / DP 2 complexes as well as an Rb / E2F 1 / DP 1 trimeric complex . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| No differences were observed between RA sensitive and RA resistant ovarian carcinoma cells in the levels of expression of many cell cycle genes including cyclin A , B and E , cdk 2 , 4 and 6 , E2F 1 , E2F 2 , E2F 3 , E2F 4 , E2F 5 , DP 1 and DP 2 . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Thus , mRNA and protein levels of E2F 1 , 3 , and 4 and DP 1 and DP 2 were down regulated during development to undetectable levels in adult myocytes . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| Here we investigated the role of E2F1 and E2F4 expression , with or without co expression of DP 1 or DP 2 , on cell proliferation in transiently transfected primary rat MCs . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| RT PCR analyses revealed that the GCN 5 deficiency exhibited opposite influences on transcriptions of G1 / S phase transition related genes , i . e . repressions for E2F 1 , E2F 3 , E2F 4 , E2F 6 , DP 2 , cyclin A , cyclin D 3 , PCNA , cdc25B and p 107 ; and activations for p 27 , c myc , cyclin D 2 and cyclin G 1 . ^^^ |
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| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| To elucidate the biochemical processes involved in the pathogenesis of B CLL and MCL , we analyzed the expression level of a set of genes that play central roles in apoptotic or cell proliferation pathways and of candidate genes from frequently altered genomic regions , namely ATM , BAX , BCL 2 , CCND 1 , CCND 3 , CDK 2 , CDK 4 , CDKN1A , CDKN1B , E2F1 , ETV 5 , MYC , RB 1 , SELL , TFDP 2 , TNFSF 10 , and TP 53 . ^^^ |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q14188 and Q01094 |
Pubmed |
SVM Score :0.0 |
| NA |
|