Pubmed abstracts for Protein-Protein Interaction search result :

Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :1.0498687
In vitro , E2F 1 formed a stable complex with cyclin A / CDK2 but not with either subunit alone . 1.0498687^^^ While the complex of cyclin A / CDK2 was required for stable complex formation with E2F 1 , the kinase active form of CDK 2 was not required . 0.70948654^^^ Because the stable association of E2F 1 with cyclin A / CDK2 in vitro and in vivo did not require a DP 1 or RB binding domain and because the interactions could be reconstituted from purified components in vitro , we conclude that the interactions between cyclin A / CDK2 and E2F 1 are direct . 0.70455913^^^ We have analyzed E2F 1 phosphorylation and its interaction with cyclin A / CDK2 complexes both in vivo and in vitro . 0.68360886^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.88115224
The transcription factor E2F 1 interacts stably with cyclin A via a small domain near its amino terminus and is negatively regulated by the cyclin A dependent kinases . 0.88115224^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In addition to the S phase genes , we also find that several genes believed to play regulatory roles in cell cycle progression , such as the cdc 2 , cyclin A , and B myb genes , are also induced by E2F1 . ^^^ Finally , we also demonstrate that a G 1 arrest brought about by gamma irradiation is overcome by the overexpression of E2F1 and that this coincides with the enhanced activation of key target genes , including the cyclin A and cyclin E genes . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Regulation of adenovirus 12 E1A transcription : E2F and ATF motifs in the E1A promoter bind nuclear protein complexes including E2F1 , DP 1 , cyclin A and / or RB and mediate transcriptional ( auto ) activation . ^^^ For HeLa , 293 , U 937 , and A 549 cells , participation of E2F 1 , DP 1 , cyclin A , and RB was involved in formation of some complexes only , assuming participation of factors different from E2F 1 or DP 1 in others . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Furthermore , overexpression of cyclin A strongly activates the MYC promoter and this effect is further enhanced by coexpression of E2F 1 and cyclin A . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Phosphorylation of the retinoblastoma protein is also increased following induction of E2F 1 / DP 1 , suggesting that E2F can feed back on the retinoblastoma protein , presumably through activation of cyclin A and / or E associated kinase activity . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Western blot analysis showed that among the E2F associated proteins , the expression of E2F 1 , cyclin A , and cyclin B but not p 107 was cell cycle and senescence dependent . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Ectopic expression of cyclin A , but not cyclins D and E or E2F 1 and 4 , can overcome the effect of rapamycin . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
We identified an E2F1 derived eight residue peptide which blocked the binding of cyclin A and E cdk 2 complexes to E2F1 and p 21 . ^^^ Mutation of the cyclin cdk 2 binding motifs in p 107 and E2F1 likewise prevented their phosphorylation by cyclin A associated kinases in vitro . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
E2F1 , the first cloned member of this family , is regulated during the cell cycle at the mRNA level by changes in transcription of the E2F1 gene and at the protein level by complex formation with proteins such as the retinoblastoma gene product ( pRB ) , cyclin A and DP 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Analyses of a series of E2F1 mutants revealed that the transcriptional activation , leucine zipper , basic , and cyclin A / Cdk2 binding domains are dispensable , but the helix loop helix region is essential for myogenic inhibition . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Deregulated expression of E2F 1 induces cyclin A and E associated kinase activities independently from cell cycle position . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
VES , although having little effect on E2F 1 steady state protein levels , decreased E2F 1 phosphorylation and transactivation activity and increased cyclin A binding to E2F 1 . ^^^ GAL 4 E2F 1 deletion mutant studies indicated that cyclin A negatively regulates E2F function . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Formation of the early region 2 transcription factor 1 retinoblastoma protein ( E2F 1 RB ) transrepressor and release of the retinoblastoma protein from nuclear complexes containing cyclin A is induced by interferon alpha in U937V cells but not in interferon alpha resistant U937VR cells . ^^^ Interestingly , treatment of nuclear extracts from logarithmically growing U937V and U937VR cells with an antiserum against cyclin A that disrupts cyclin A containing complexes , led to the formation of the E2F 1 RB complex , suggesting the presence of under phosphorylated ( active ) RB , trapped in nuclear complexes that contain cyclin A . ^^^ We conclude that the missing induction of the E2F 1 RB transrepressor by IFN alpha and the failure to release RB from cyclin A containing complexes might contribute to the resistance of U937VR cells to the antiproliferative effects of IFN alpha . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
The elevation of these complexes in arrested 5 mos transformed cells may be the cause of the transcriptional activation of the E2F regulated genes cdc 2 , DHFR , cyclin A , and E2F1 seen in serum starved 5 mos transformed cells . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Western blot analysis of BIP with cyclins / CDKs and E2F antisera indicated association with cdc 2 , cdk 2 , cdk 4 , cyclin B , cyclin D , cyclin A and E2F 4 but not with cdk 3 , cdk 5 , cdk 6 , E2F 1 , E2F 2 , E2F 3 , E2F 5 and cyclin E . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In the search for new risk factors at the molecular and cellular levels , clinical data [ lymph node involvement ( LN ) and stage ] were used and 104 squamous cell lung carcinomas were analyzed by immuno histochemistry for expression of cyclin D 1 , cyclin A , cdk 2 , cdk 4 , RB , and E2F1 . ^^^ The results of the univariate analysis of all 8 factors showed that cyclin A and cdk 2 gave the best prognostic information , while no prognostic value could be found associated with cyclin D 1 , cdk 4 , RB and E2F1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In agreement with this conclusion , we find that the cyclin A promoter only poorly interacts with E2F 4 , which is the major E2F family member in G 0 cells , while a clear binding is seen with E2F 1 and 3 , which are up regulated in late G1 . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In addition , fibroblasts constitutively expressing a mutant E2F1 transcription factor ( E2F1d87 ) have a lengthened S phase , due to a truncation of the cyclin A / cdk2 binding domain . ^^^ Thus , although the fibronectin signaling mechanisms culminating in elevated cyclin A were intact in these mutant E2F1 expressing cells , they were insensitive to the effects of this elevated cyclin A . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Interestingly , we find that the histone H 1 kinase activity associated with an E2F 1 complex containing Cyclin A and Cdk 2 , but not that associated with Cyclin E , in late G 1 and early S phases is increased in cells containing hormone activated MycER , but not FosER . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
However , these cells fail to express the late G 1 genes as E2F 1 , cdc25A , and cyclin A in response to mitogen stimulation . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Coimmunoprecipitation analyses revealed an interaction of C / EBPalpha with p 107 but none with cdk 2 , E2F1 , or cyclin A . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
E2F 1 has properties of a radiosensitizer and its regulation by cyclin A kinase is required for cell survival of fibrosarcoma cells lacking p 53 . ^^^ Negative regulation of E2F 1 DNA binding function by cyclin A kinase represents part of an S phase checkpoint control system that , when activated , leads to apoptosis . ^^^ In this study , we examined the cellular sensitivity and resistance of isogenic mouse fibrosarcoma cell lines , differing primarily in their p 53 status , to ectopic expression of wild type ( wt ) E2F 1 and cyclin A kinase binding defective mutants of it . ^^^ In contrast , expression of cyclin A kinase binding defective E2F 1 species interfered with cell survival of fibrosarcoma cells irrespective of their p 53 status . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Expression of the cell cycle specific proteins pRb , Rb2 / p130 , p 107 , cyclin A , cdc 2 , and E2F 1 was decreased after DeltaRaf 1 : ER activation in DMS 53 cells . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
DP 1 phosphorylation in multimeric complexes : weaker interaction with cyclin A through the E2F1 cyclin A binding domain leads to more efficient phosphorylation than stronger interaction through the p 107 cyclin A binding domain . ^^^ In contrast , DP 1 was efficiently phosphorylated when weakly connected to cyclin A Cdk 2 via E2F1 or E2F4 with a fused cyclin A binding domain of E2F1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
No difference in the treatment induced modulation of proteins involved in cell cycle progression ( cyclin A , cdk 2 , pRB , E2F 1 ) and apoptosis ( bcl 2 , bax ) was observed in the three clones . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Cyclin A , which binds to E2F 1 in close vicinity to Sp 1 does not interfere with this interaction . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Furthermore , E2F1 overexpression increased the promoter activities and protein expressions of G 1 cyclins , cyclin D 1 , cyclin E , cyclin A . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
We have been able to identify a number of genes , including B myb , cyclin A , cdc 2 , cdc 6 , and DHFR , whose expression is dependent on the presence of E2F3 but not E2F1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Although exposure of the normal mammary cells to CD 437 does not result in modulation of cyclin A or cdk 2 levels , an increase in E2F 1 levels and a marked inhibition of cyclin A / cdk2 kinase activity are observed . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
RB2 / p130 induction also decreased cyclin A and the transcription factor E2F 1 while increasing cyclin E at both the transcriptional and protein levels of expression . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In agreement with these findings , the level of the cyclin dependent kinase inhibitor p 27 ( KIP 1 ) is increased in response to preussin treatment while the expression of both cyclin A and the transcription factor E2F 1 is down regulated . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
TSA enhanced the protein expression of p 21 ( WAF 1 ) , CREB binding protein , cyclinE , cyclin A , Bak and Bax , while it reduced the expression of E2F 1 , E2F 4 , HDAC 1 , p 53 and hyperphosphorylated form of Rb . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Notwithstanding the continuous presence of E2F 1 , the cell cycle dependent expression of cyclin A , cyclin B 1 , cyclin D 1 , cyclin E , and proliferating cell nuclear antigen was restored with a pattern equivalent to that associated with cytokine stimulation . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Consistent with these findings , PCA 4230 repressed serum inducible cyclin A promoter activity , and overexpression of either cyclin D 1 or E2F1 efficiently circumvented this inhibitory effect . ^^^ Importantly , adenovirus mediated overexpression of E2F1 restored S phase entry in PCA 4230 treated VSMCs , demonstrating that PCA 4230 represses cyclin A gene expression and VSMC growth via inhibition of the cyclin D1 / E2F pathway . 3 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
E2F1 mediated neuronal apoptosis did not require activation of gene transcription because : ( 1 ) ectopic expression of E2F1 or its mutants lacking the transactivation domain induced neuronal apoptosis , whereas an E2F1 mutant lacking the DNA binding domain did not ; ( 2 ) under all of these conditions , known E2F1 target genes including cyclin A , cdc 2 and p 19 ( ARF ) were not induced ; and ( 3 ) DA evoked neuronal apoptosis was associated with up regulated E2F1 , but not transcription of its target genes . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Accompanying this is a reduction in the E2F 1 regulated expression of cell cycle genes such as c myc , cyclin D 1 , cyclin A and cyclin B 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
We demonstrate here that the E2F1 induced by DNA damage can bind to and promote the apoptotic function of p 53 via the cyclin A binding site of E2F1 . ^^^ Cyclin A , but not cyclin E , prevents E2F1 from interacting and cooperating with p 53 to induce apoptosis . ^^^ However , in response to DNA damage , cyclin A levels decrease , with a concomitant increase in E2F1 p 53 complex formation . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
No differences were observed between RA sensitive and RA resistant ovarian carcinoma cells in the levels of expression of many cell cycle genes including cyclin A , B and E , cdk 2 , 4 and 6 , E2F 1 , E2F 2 , E2F 3 , E2F 4 , E2F 5 , DP 1 and DP 2 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Among the mechanisms that modulate the activity of the E2F proteins , cyclin A has been found to be important for the down regulation of E2F 1 , 2 , and 3A activity after cells have progressed through G ( 1 ) / S . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In serum stimulated ( S phase ) cells , the composition of the complex switched to E2F1 / 4 , DP 1 and p 107 , together with cyclin A and cyclin dependent kinase 2 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Our results show that the expression of RB C pocket fragments not only induces delayed cell cycle progression , which is mediated by the down regulation of cyclin A , cyclin E , and E2F 1 , but also sensitizes cells to apoptosis through p 53 dependent pathways . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
This G 1 arrest is associated with down regulation of a subset of E2F targets including cyclin A , E2F1 and CDC 6 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
To determine additional sequence specificity motifs around the RXL sequence , we have performed 10 ray crystallographic studies at 2 . 3 A resolution and isothermal calorimetry measurements on complexes of phospho CDK2 / cyclin A with a recruitment peptide derived from E2F1 and with shorter 11 mer peptides from p 53 , pRb , p 27 , E2F1 , and p 107 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Compared with normal cells , SCID cells contained slightly higher levels of transcripts of cyclin A , cyclin E , B Myb and dihydrofolate reductase , which are regulated by E2F 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Inhibition of cyclin A kinase activity in E2F 1 chemogene therapy of colon cancer . ^^^ The apoptotic function of E2F 1 is dependent on its ability to bind DNA ; cyclin A kinase activity has been shown to negatively regulate the DNA binding capacity of E2F 1 . ^^^ In the present study , we sought to determine whether cyclin A kinase activity is involved in mediating the interaction between E2F 1 and chemotherapeutic agents in colon cancer cells . ^^^ E2F 1 overexpression and cyclin A protein expression were monitored by immunoblot , and cyclin A kinase activity was determined by kinase assay . ^^^ Ad E2F 1 treatment alone results in 3 . 4 fold increase of cyclin A kinase activity compared to Ad LacZ control ( p < 0 . 05 ) ; when combined with chemotherapeutic agents , cyclin A kinase activity was inhibited significantly by VIN , actinomycin D , and etoposide ( p < 0 . 005 ) , but not with CPT , CIS , and 5 FU ( p > 0 . 1 ) compared to Ad E2F 1 treatment alone . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
S / K deprivation induced the expression of cell cycle proteins such as cyclin E , cyclin A , cdk 2 , cdk 4 and E2F 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
The reduction in c MYC and CYCLIN D 1 expression by aODNs , was associated with a > 50 % decrease in E2F1 mRNA and protein production , without changes in CYCLIN A and CYCLIN E expression . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Flavopiridol induced apoptosis during S phase requires E2F 1 and inhibition of cyclin A dependent kinase activity . ^^^ During S phase , cyclin A dependent kinase activity neutralizes E2F 1 allowing orderly S phase progression . ^^^ Inhibition of cyclin A dependent kinase by flavopiridol could cause inappropriately persistent E2F 1 activity during S phase traversal and exit . ^^^ Transformed cells , with high baseline levels of E2F 1 activity , may be particularly sensitive to cyclin A dependent kinase inhibition , as the residual level of E2F 1 activity that persists may be sufficient to induce apoptosis . ^^^ Finally , the response to flavopiridol during S phase is blunted in cells expressing a nonphosphorylatable E2F 1 mutant incapable of binding cyclin A , suggesting that the modulation of E2F 1 activity produced by flavopiridol mediated cyclin dependent kinase inhibition is critical for the apoptotic response of S phase cells . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
More significantly , physical association of PARP 1 and E2F 1 in vivo also occurred in wild type fibroblasts 5 h after re entry into S phase , coincident with the increase in E2F 1 promoter activity and expression of E2F 1 responsive S phase genes cyclin A and c Myc . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
When CDK 2 activity was bypassed by activation of the ER E2F1 fusion protein , cAMP no longer inhibited expression of Cdc25A or cyclin A but still inhibited DNA synthesis . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin like growth factor 1 induction of new E2F 1 synthesis . ^^^ Here we explored the hypothesis that new synthesis of E2F 1 is required for insulin like growth factor 1 ( IGF 1 ) to induce cyclin A accumulation and RB hyperphosphorylation , events that are targeted by tumor necrosis factor alpha ( TNFalpha ) to arrest cell cycle progression . ^^^ We first established that IGF 1 increases expression of cyclin A , causes hyperphosphorylation of RB , and augments the mass of E2F 1 in a time dependent manner . ^^^ Most important , this E2F 1 small interfering RNA also blocks the ability of IGF 1 to increase cyclin A accumulation and to hyperphosphorylate RB . ^^^ TNFalpha antagonizes the ability of IGF 1 to increase mass of both E2F 1 and cyclin A but not cyclin E or D 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
This study suggests that , in fruit fly embryos , 1 ) there is a dose dependent relationship between cell cycle length and O 2 levels in fruit fly embryos , and 2 ) stabilized cyclin A and E2F1 are likely to be the mediators of hypoxia induced arrest at metaphase and pre S phase . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Over expression of E2F 1 , cyclin D 1 , Cdk 2 , Cdk 4 and cyclin A was found in 64 % ( 30 of 46 ) , 43 % ( 26 of 46 ) , 28 % ( 11 of 46 ) , 71 % ( 33 of 46 ) and 63 % ( 29 of 46 ) of HCCs examined respectively and this was correlated with elevation of ERK . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Overexpression of both viral proteins induces cellular proliferation , retinoblastoma ( pRb ) phosphorylation , and accumulation of products of genes that are negatively regulated by pRb , such as p 16 ( INK4a ) , CDC 2 , E2F 1 , and cyclin A . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
RT PCR analyses revealed that the GCN 5 deficiency exhibited opposite influences on transcriptions of G1 / S phase transition related genes , i . e . repressions for E2F 1 , E2F 3 , E2F 4 , E2F 6 , DP 2 , cyclin A , cyclin D 3 , PCNA , cdc25B and p 107 ; and activations for p 27 , c myc , cyclin D 2 and cyclin G 1 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Quantitative real time PCR revealed that E2F1 , E2F2 , E2F3 , and E2F4 alleviate G 0 arrest by induction of cyclinA and E cyclins . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Moreover , the compound suppressed high glucose induced E2F DNA binding activity , and the expression of E2F1 , E2F2 , cyclin A , and PCNA proteins . ^^^ These data suggest that the beneficial effects of cilostazol on high glucose stimulated proliferation of VSMCs are mediated by the downregulation of E2F activity and expression of its downstream target genes , including E2F1 , E2F2 , cyclin A , and PCNA . . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
These effects were associated with reduced cyclin A and cyclin B dependent kinase activities and reduced phosphorylation of the retinoblastoma protein ( pRb ) as well as decreased protein levels of cyclins A , B , and E , the transcription factor E2F1 , and the cyclin dependent kinase inhibitor p 21 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
This regulation of p 53 by E2F1 is cell cycle dependent , as the cellular distribution of Ser 315 phosphorylated p 53 is associated with the periodic expression of E2F and cyclin A throughout the cell cycle . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
This amazing synergism was accompanied by synergistic modulation of E2F 1 and p 27 ( Kip 1 ) , which were reported to mediate the anticancer activities of lovastatin and troglitazone , respectively , and other cell cycle regulating proteins such as CDK 2 , cyclin A and RB phosphorylation status . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
In contrast to E2F1 and cyclin A 2 , which were induced and co localized with c myc expression , induction of cyclins D 1 and E occurred only in these tumor foci . ^^^ These results suggest that E2F1 and cyclin A 2 may be induced by c Myc to mediate the onset of mammary cancer , whereas overexpression of cyclins D 1 and E may occur later to facilitate tumor progression . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
Despite the accumulation of hematopoietic progenitor cells in S phase , the combined loss of E2F1 and E2F2 results in significantly decreased expression and activities of several E2F target genes including cyclin A 2 . ^^^
Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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Interacting proteins: P20248 and Q01094	Pubmed	SVM Score :0.0
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