| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| NA |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :1.050019 |
| Previous studies using affinity chromatography techniques have shown that the activation domains of certain activators , including the acidic activation domain of E2F 1 , can interact with TBP in the absence of DNA . 1.050019^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| In yolk , several transcription factors , GATA 2 , E2F 1 , MyoD , and TFIID , were developmentally regulated . ^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| We have characterized interactions of the E2F1 activation domain with two general transcription factors , the TATA box binding protein ( TBP ) and TFIIH . ^^^ Modular organization of the E2F1 activation domain and its interaction with general transcription factors TBP and TFIIH . ^^^ Two distinct binding sites on E2F1 were identified for TBP ( amino acids 386 417 and 415 437 ) each of which supported activation in mammalian cells when expressed as a fusion to a heterologous DNA binding domain . ^^^ We have demonstrated that recombinant Rb can compete with TBP and the p 62 subunit of TFIIH for binding to immobilized E2F1 . ^^^ A tumorigenic form of Rb deficient in repressing E2F1 mediated transactivation is likewise deficient in displacing TBP from E2F1 . ^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| Nine transcription factors were detected ATF 2 , SRE ZBP , GATA 2 , TFIID , Ets 1 / Ets 2 , E2F 1 , Oct 2 , p 53 , and AP 2 ; four transcription factors were not detected Myo D , CREB , Sp 2 , and Wilms ' tumor . ^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| Overexpression of D type cyclins , E2F 1 , SV 40 large T antigen and HPV 16 E7 rescue cell cycle arrest of tsBN 462 cells caused by the CCG1 / TAF ( 2 ) 250 mutation . tsBN 462 cells , which have a point mutation in CCG1 / TAF ( 2 ) 250 , a component of TFIID complex , arrest in G 1 at the nonpermissive temperature of 39 . 5 degrees C . ^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| Functional analysis of the E2F1 core domain demonstrated that replacement of phenylalanine residues 413 , 425 , and 429 with alanine reduces both transcriptional activation of the dhfr promoter and protein protein interactions with CBP , transcription factor ( TF ) IIH , and TATA binding protein ( TBP ) . ^^^ |
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| Interacting proteins: Q01094 and P20226 |
Pubmed |
SVM Score :0.0 |
| In addition , three TFs decreased within the range of 33 50 % ( TFIID , E2F1 , CREB ) and two TFs increased within the range of 50 100 % ( PAX 5 , Stat 4 ) . ^^^ |
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