| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| In addition , six novel targets were detected : cyclin D 1 ( CCND 1 ) , cell division protein kinase 6 , collagen 8 alpha 1 subunit , CD 59 glycoprotein precursor , integrin beta 8 , and interleukin 6 precursor IFN beta 2 . ^^^ We found no evidence that CCND 1 , cell division protein kinase 6 , CD 59 , and integrin beta 8 expression was influenced by hypoxia suggesting that pVHL down regulates these targets by a HIF independent mechanism . ^^^ |
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| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| In the glioblastomas with no alterations of CDKN2A , CDK 4 or RB 1 , several other genes ( CCND 1 , CCND 2 , CCND 3 , CDK 6 , E2F , CDK 7 , MYC and MYCN ) whose products take part in cell cycle regulation were examined . ^^^ |
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| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| Furthermore , the cell cycle regulator genes such as CDK 6 , CCND 1 , CDC27HS , CDC16HS , Wee1Hu , MAPKK 1 , and IGFBP 6 were expressed with decreased levels in the drug resistant cell line . ^^^ |
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| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| The expression status of the three cyclin D genes ( CCND 1 , CCND 2 and CCND 3 ) , the two cyclin D dependent kinase genes ( CDK 4 and CDK 6 ) and the p 16 ( INK4a ) gene was studied in a series of 47 Wilms ' tumors , 16 normal mature kidneys and two fetal kidneys . ^^^ |
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| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| Here we show that in a squamous carcinoma cell line with 11 fold amplification of the CCND 1 gene , cyclin D 1 associates specifically with p33cdk4 ( PSK J 3 ) and p38cdk6 ( PLSTIRE ) , two closely related members of the cyclin dependent kinase ( CDK ) family . ^^^ |
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| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| NA |
|
| Interacting proteins: Q00534 and P24385 |
Pubmed |
SVM Score :0.0 |
| NA |
|